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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
SPT15
  • nucleus
  • RNA polymerase I transcription factor complex
  • transcription factor TFIID complex
  • transcription factor TFIIIB complex
  • transcription from RNA polymerase III promoter
  • transcription initiation from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
  • transcription initiation from RNA polymerase II promoter
  • DNA binding
  • RNA polymerase I transcription factor activity
  • protein homodimerization activity
  • general RNA polymerase II transcription factor activity
  • DNA bending activity
  • RNA polymerase III transcription factor activity
  • TAF1
  • transcription factor TFIID complex
  • protein amino acid phosphorylation
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • histone acetyltransferase activity
  • general RNA polymerase II transcription factor activity
  • protein serine/threonine kinase activity
  • TAF11
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF12
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF3
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF4
  • transcription factor TFIID complex
  • transcription from RNA polymerase II promoter
  • RNA polymerase II transcription factor activity
  • TAF5
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF6
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF9
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    transcription factor TFIID complex 1.1818E-25 9 15 9 6292
    DNA-directed RNA polymerase II, holoenzyme 1.7889E-19 9 56 9 6292
    transcription factor complex 1.7585E-18 9 71 9 6292
    nucleoplasm part 1.7837E-13 9 245 9 6292
    nucleoplasm 3.5315E-13 9 264 9 6292
    nuclear lumen 4.8255E-11 9 453 9 6292
    organelle lumen 1.4638E-9 9 660 9 6292
    intracellular organelle lumen 1.4638E-9 9 660 9 6292
    membrane-enclosed lumen 2.4937E-9 9 700 9 6292
    SLIK (SAGA-like) complex 3.4881E-9 9 16 4 6292
    SAGA complex 1.3966E-8 9 22 4 6292
    SAGA-type complex 1.6896E-8 9 23 4 6292
    nuclear part 1.5218E-7 9 1103 9 6292
    protein complex 2.0019E-7 9 1137 9 6292
    histone acetyltransferase complex 2.5557E-7 9 44 4 6292
    macromolecular complex 5.3146E-6 9 1635 9 6292
    nucleus 3.9292E-5 9 2041 9 6292
    organelle part 1.0749E-4 9 2282 9 6292
    intracellular organelle part 1.0749E-4 9 2282 9 6292
    transcription factor TFIIIB complex 4.2857E-3 9 3 1 6292
    membrane-bounded organelle 9.9391E-3 9 3771 9 6292
    intracellular membrane-bounded organelle 9.9391E-3 9 3771 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    regulation of transcription involved in G1 phase of mitotic cell cycle 1.5972E-18 9 14 7 6292
    transcription initiation from RNA polymerase II promoter 4.6403E-17 9 47 8 6292
    transcription initiation 2.8241E-16 9 58 8 6292
    G1 phase of mitotic cell cycle 4.1178E-16 9 27 7 6292
    G1 phase 4.1178E-16 9 27 7 6292
    protein complex biogenesis 9.9918E-13 9 155 8 6292
    protein complex assembly 9.9918E-13 9 155 8 6292
    transcription from RNA polymerase II promoter 3.1026E-12 9 335 9 6292
    interphase of mitotic cell cycle 5.841E-12 9 97 7 6292
    interphase 5.841E-12 9 97 7 6292
    macromolecular complex assembly 1.2438E-10 9 281 8 6292
    transcription, DNA-dependent 1.2481E-10 9 503 9 6292
    RNA biosynthetic process 1.3652E-10 9 508 9 6292
    transcription 2.8998E-10 9 552 9 6292
    macromolecular complex subunit organization 8.5295E-10 9 357 8 6292
    cellular component assembly 1.563E-9 9 385 8 6292
    regulation of transcription from RNA polymerase II promoter 2.5366E-9 9 228 7 6292
    mitotic cell cycle 5.5645E-9 9 255 7 6292
    RNA metabolic process 4.101E-8 9 954 9 6292
    regulation of transcription, DNA-dependent 5.9468E-8 9 358 7 6292
    regulation of RNA metabolic process 6.5488E-8 9 363 7 6292
    cell cycle phase 8.3629E-8 9 376 7 6292
    regulation of transcription 9.6795E-8 9 384 7 6292
    histone acetylation 1.1146E-7 9 36 4 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.6585E-7 9 415 7 6292
    regulation of nitrogen compound metabolic process 1.6863E-7 9 416 7 6292
    cellular component biogenesis 1.7172E-7 9 694 8 6292
    regulation of gene expression 2.6886E-7 9 445 7 6292
    cellular macromolecule biosynthetic process 2.9528E-7 9 1187 9 6292
    macromolecule biosynthetic process 2.9981E-7 9 1189 9 6292
    protein amino acid acetylation 3.0682E-7 9 46 4 6292
    regulation of macromolecule biosynthetic process 3.1831E-7 9 456 7 6292
    regulation of cellular biosynthetic process 4.0393E-7 9 472 7 6292
    regulation of biosynthetic process 4.0988E-7 9 473 7 6292
    regulation of macromolecule metabolic process 5.0842E-7 9 488 7 6292
    cell cycle process 5.2297E-7 9 490 7 6292
    gene expression 5.9596E-7 9 1283 9 6292
    regulation of primary metabolic process 7.2713E-7 9 514 7 6292
    cell cycle 8.4125E-7 9 525 7 6292
    protein amino acid acylation 8.4865E-7 9 59 4 6292
    regulation of cellular metabolic process 9.7027E-7 9 536 7 6292
    regulation of metabolic process 1.1157E-6 9 547 7 6292
    nucleic acid metabolic process 1.4425E-6 9 1415 9 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.6017E-6 9 1566 9 6292
    cellular biosynthetic process 3.6225E-6 9 1567 9 6292
    covalent chromatin modification 4.2681E-6 9 88 4 6292
    histone modification 4.2681E-6 9 88 4 6292
    biosynthetic process 4.4215E-6 9 1602 9 6292
    cellular nitrogen compound metabolic process 1.0872E-5 9 1770 9 6292
    nitrogen compound metabolic process 1.2092E-5 9 1791 9 6292
    regulation of cellular process 1.446E-5 9 796 7 6292
    regulation of biological process 1.8275E-5 9 824 7 6292
    chromatin modification 5.5658E-5 9 168 4 6292
    post-translational protein modification 5.9621E-5 9 357 5 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    cellular component organization 1.1027E-4 9 1582 8 6292
    chromatin organization 1.1671E-4 9 203 4 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    biological regulation 2.4341E-4 9 1213 7 6292
    protein modification process 2.962E-4 9 499 5 6292
    macromolecule modification 5.5019E-4 9 569 5 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    metabolic process 2.004E-3 9 3157 9 6292
    chromosome organization 5.2635E-3 9 555 4 6292
    cellular protein metabolic process 9.8781E-3 9 1074 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA polymerase II transcription factor activity 5.1988E-16 9 130 9 6292
    general RNA polymerase II transcription factor activity 6.5157E-16 9 64 8 6292
    transcription regulator activity 3.4568E-12 9 339 9 6292
    protein homodimerization activity 2.859E-3 9 2 1 6292
    identical protein binding 4.2857E-3 9 3 1 6292
    protein dimerization activity 8.5551E-3 9 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle