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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.9846E-16 13 101 10 6292
    cytosolic part 1.4105E-15 13 122 10 6292
    ribosomal subunit 9.0027E-14 13 183 10 6292
    cytosol 7.6291E-12 13 284 10 6292
    cytosolic large ribosomal subunit 8.211E-12 13 60 7 6292
    ribosome 9.4091E-12 13 290 10 6292
    ribonucleoprotein complex 6.5586E-11 13 514 11 6292
    large ribosomal subunit 6.486E-10 13 110 7 6292
    preribosome 4.9105E-7 13 34 4 6292
    non-membrane-bounded organelle 1.1943E-6 13 959 10 6292
    intracellular non-membrane-bounded organelle 1.1943E-6 13 959 10 6292
    90S preribosome 4.609E-6 13 17 3 6292
    macromolecular complex 1.6165E-5 13 1635 11 6292
    cytosolic small ribosomal subunit 5.5762E-5 13 38 3 6292
    small ribosomal subunit 3.9426E-4 13 73 3 6292
    organelle part 3.3831E-3 13 2282 10 6292
    intracellular organelle part 3.3831E-3 13 2282 10 6292
    cytoplasmic part 6.8899E-3 13 2482 10 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.0173E-16 13 376 13 6292
    cellular protein metabolic process 9.8294E-11 13 1074 13 6292
    protein metabolic process 2.047E-10 13 1136 13 6292
    cellular macromolecule biosynthetic process 3.6337E-10 13 1187 13 6292
    macromolecule biosynthetic process 3.7146E-10 13 1189 13 6292
    gene expression 1.0037E-9 13 1283 13 6292
    cellular biosynthetic process 1.3657E-8 13 1567 13 6292
    biosynthetic process 1.822E-8 13 1602 13 6292
    ribosomal large subunit assembly 1.0637E-6 13 41 4 6292
    cellular macromolecule metabolic process 1.8698E-6 13 2285 13 6292
    macromolecule metabolic process 2.6802E-6 13 2349 13 6292
    ribosomal subunit assembly 3.5251E-6 13 55 4 6292
    ribosome assembly 6.4995E-6 13 64 4 6292
    ribosomal large subunit biogenesis 6.9177E-6 13 65 4 6292
    organelle assembly 8.7925E-6 13 69 4 6292
    ribonucleoprotein complex assembly 2.7675E-5 13 92 4 6292
    primary metabolic process 4.1002E-5 13 2896 13 6292
    cellular metabolic process 7.4867E-5 13 3033 13 6292
    metabolic process 1.2617E-4 13 3157 13 6292
    regulation of translation 1.8907E-4 13 57 3 6292
    posttranscriptional regulation of gene expression 2.3144E-4 13 61 3 6292
    regulation of cellular protein metabolic process 3.1959E-4 13 68 3 6292
    cellular macromolecular complex assembly 3.9465E-4 13 182 4 6292
    regulation of protein metabolic process 4.1043E-4 13 74 3 6292
    ribosome biogenesis 4.3563E-4 13 346 5 6292
    ribonucleoprotein complex biogenesis 6.2467E-4 13 374 5 6292
    cellular macromolecular complex subunit organization 1.4943E-3 13 259 4 6292
    macromolecular complex assembly 2.0214E-3 13 281 4 6292
    macromolecular complex subunit organization 4.8383E-3 13 357 4 6292
    cellular component assembly 6.3393E-3 13 385 4 6292
    cellular component biogenesis 9.7186E-3 13 694 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 5.0174E-20 13 212 13 6292
    structural molecule activity 2.5855E-17 13 339 13 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle