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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 14 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL16A
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL30
  • cytoplasm
  • negative regulation of nuclear mRNA splicing, via spliceosome
  • rRNA processing
  • negative regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS22A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 6.8544E-16 14 101 10 6292
    cytosolic part 4.8568E-15 14 122 10 6292
    ribosomal subunit 3.0721E-13 14 183 10 6292
    cytosolic large ribosomal subunit 1.6301E-11 14 60 7 6292
    cytosol 2.5644E-11 14 284 10 6292
    ribosome 3.1598E-11 14 290 10 6292
    ribonucleoprotein complex 2.8362E-10 14 514 11 6292
    large ribosomal subunit 1.2786E-9 14 110 7 6292
    non-membrane-bounded organelle 3.608E-6 14 959 10 6292
    intracellular non-membrane-bounded organelle 3.608E-6 14 959 10 6292
    macromolecular complex 5.7632E-5 14 1635 11 6292
    cytosolic small ribosomal subunit 7.0675E-5 14 38 3 6292
    small ribosomal subunit 4.9762E-4 14 73 3 6292
    90S preribosome 6.135E-4 14 17 2 6292
    preribosome 2.4766E-3 14 34 2 6292
    organelle part 7.9969E-3 14 2282 10 6292
    intracellular organelle part 7.9969E-3 14 2282 10 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 5.8814E-18 14 376 14 6292
    cellular protein metabolic process 1.6609E-11 14 1074 14 6292
    protein metabolic process 3.6611E-11 14 1136 14 6292
    cellular macromolecule biosynthetic process 6.7941E-11 14 1187 14 6292
    macromolecule biosynthetic process 6.957E-11 14 1189 14 6292
    gene expression 2.03E-10 14 1283 14 6292
    cellular biosynthetic process 3.38E-9 14 1567 14 6292
    biosynthetic process 4.6108E-9 14 1602 14 6292
    regulation of translation 9.6002E-8 14 57 5 6292
    posttranscriptional regulation of gene expression 1.3575E-7 14 61 5 6292
    regulation of cellular protein metabolic process 2.3587E-7 14 68 5 6292
    regulation of protein metabolic process 3.6188E-7 14 74 5 6292
    cellular macromolecule metabolic process 6.7658E-7 14 2285 14 6292
    macromolecule metabolic process 9.9712E-7 14 2349 14 6292
    primary metabolic process 1.8826E-5 14 2896 14 6292
    cellular metabolic process 3.6009E-5 14 3033 14 6292
    metabolic process 6.3176E-5 14 3157 14 6292
    ribosomal large subunit assembly 8.8955E-5 14 41 3 6292
    ribosomal subunit assembly 2.1493E-4 14 55 3 6292
    ribosome assembly 3.3732E-4 14 64 3 6292
    ribosomal large subunit biogenesis 3.5317E-4 14 65 3 6292
    organelle assembly 4.2141E-4 14 69 3 6292
    ribosome biogenesis 6.4733E-4 14 346 5 6292
    ribonucleoprotein complex biogenesis 9.2471E-4 14 374 5 6292
    ribonucleoprotein complex assembly 9.7992E-4 14 92 3 6292
    regulation of gene expression 2.0276E-3 14 445 5 6292
    negative regulation of mRNA processing 2.225E-3 14 1 1 6292
    negative regulation of nuclear mRNA splicing, via spliceosome 2.225E-3 14 1 1 6292
    negative regulation of RNA splicing 2.225E-3 14 1 1 6292
    regulation of macromolecule biosynthetic process 2.2609E-3 14 456 5 6292
    regulation of cellular biosynthetic process 2.6351E-3 14 472 5 6292
    regulation of biosynthetic process 2.6599E-3 14 473 5 6292
    regulation of macromolecule metabolic process 3.0535E-3 14 488 5 6292
    regulation of primary metabolic process 3.8353E-3 14 514 5 6292
    regulation of mRNA processing 4.4455E-3 14 2 1 6292
    regulation of RNA splicing 4.4455E-3 14 2 1 6292
    regulation of nuclear mRNA splicing, via spliceosome 4.4455E-3 14 2 1 6292
    regulation of cellular metabolic process 4.604E-3 14 536 5 6292
    regulation of metabolic process 5.028E-3 14 547 5 6292
    cellular macromolecular complex assembly 6.8483E-3 14 182 3 6292
    cellular process 7.2188E-3 14 4426 14 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.5902E-21 14 212 14 6292
    structural molecule activity 1.3424E-18 14 339 14 6292
    RNA binding 7.1404E-3 14 367 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle