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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL30
  • cytoplasm
  • negative regulation of nuclear mRNA splicing, via spliceosome
  • rRNA processing
  • negative regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.5642E-12 12 101 8 6292
    cytosolic part 7.3636E-12 12 122 8 6292
    ribosomal subunit 1.9721E-10 12 183 8 6292
    cytosol 6.6135E-9 12 284 8 6292
    ribosome 7.8062E-9 12 290 8 6292
    90S preribosome 1.782E-8 12 17 4 6292
    ribonucleoprotein complex 2.6676E-8 12 514 9 6292
    preribosome 3.4126E-7 12 34 4 6292
    cytosolic small ribosomal subunit 5.4096E-7 12 38 4 6292
    cytosolic large ribosomal subunit 3.4942E-6 12 60 4 6292
    small ribosomal subunit 7.696E-6 12 73 4 6292
    large ribosomal subunit 3.93E-5 12 110 4 6292
    non-membrane-bounded organelle 7.9037E-5 12 959 8 6292
    intracellular non-membrane-bounded organelle 7.9037E-5 12 959 8 6292
    macromolecular complex 5.2917E-4 12 1635 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.7552E-15 12 376 12 6292
    cellular protein metabolic process 5.8125E-10 12 1074 12 6292
    protein metabolic process 1.1437E-9 12 1136 12 6292
    cellular macromolecule biosynthetic process 1.9421E-9 12 1187 12 6292
    macromolecule biosynthetic process 1.9819E-9 12 1189 12 6292
    gene expression 4.9591E-9 12 1283 12 6292
    regulation of translation 3.8507E-8 12 57 5 6292
    posttranscriptional regulation of gene expression 5.4508E-8 12 61 5 6292
    cellular biosynthetic process 5.5155E-8 12 1567 12 6292
    biosynthetic process 7.1963E-8 12 1602 12 6292
    regulation of cellular protein metabolic process 9.4887E-8 12 68 5 6292
    regulation of protein metabolic process 1.4581E-7 12 74 5 6292
    cellular macromolecule metabolic process 5.1661E-6 12 2285 12 6292
    macromolecule metabolic process 7.2022E-6 12 2349 12 6292
    primary metabolic process 8.9282E-5 12 2896 12 6292
    ribosomal subunit assembly 1.3153E-4 12 55 3 6292
    cellular metabolic process 1.5563E-4 12 3033 12 6292
    ribosome assembly 2.0686E-4 12 64 3 6292
    metabolic process 2.5194E-4 12 3157 12 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.571E-4 12 13 2 6292
    organelle assembly 2.5874E-4 12 69 3 6292
    ribosome biogenesis 2.8065E-4 12 346 5 6292
    ribonucleoprotein complex biogenesis 4.0398E-4 12 374 5 6292
    ribonucleoprotein complex assembly 6.0496E-4 12 92 3 6292
    regulation of gene expression 9.0312E-4 12 445 5 6292
    regulation of macromolecule biosynthetic process 1.0101E-3 12 456 5 6292
    regulation of cellular biosynthetic process 1.1824E-3 12 472 5 6292
    regulation of biosynthetic process 1.1939E-3 12 473 5 6292
    regulation of macromolecule metabolic process 1.3762E-3 12 488 5 6292
    rRNA processing 1.5818E-3 12 128 3 6292
    regulation of primary metabolic process 1.7409E-3 12 514 5 6292
    negative regulation of mRNA processing 1.9072E-3 12 1 1 6292
    negative regulation of nuclear mRNA splicing, via spliceosome 1.9072E-3 12 1 1 6292
    negative regulation of RNA splicing 1.9072E-3 12 1 1 6292
    rRNA metabolic process 1.9237E-3 12 137 3 6292
    regulation of cellular metabolic process 2.1025E-3 12 536 5 6292
    regulation of metabolic process 2.3031E-3 12 547 5 6292
    ribosomal large subunit assembly 2.6238E-3 12 41 2 6292
    regulation of mRNA processing 3.811E-3 12 2 1 6292
    regulation of RNA splicing 3.811E-3 12 2 1 6292
    regulation of nuclear mRNA splicing, via spliceosome 3.811E-3 12 2 1 6292
    cellular macromolecular complex assembly 4.3192E-3 12 182 3 6292
    maturation of SSU-rRNA 5.3712E-3 12 59 2 6292
    ribosomal large subunit biogenesis 6.4883E-3 12 65 2 6292
    cellular component biogenesis 6.5683E-3 12 694 5 6292
    ncRNA processing 6.8876E-3 12 215 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.5755E-18 12 212 12 6292
    structural molecule activity 4.9655E-16 12 339 12 6292
    rRNA binding 3.9428E-4 12 16 2 6292
    RNA binding 3.8749E-3 12 367 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle