YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 14 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL16A
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL17B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS18B, RPS18A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • mitochondrion
  • ribosome
  • intracellular
  • rRNA export from nucleus
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • nucleic acid binding
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 3.6592E-18 14 101 11 6292
    cytosolic part 3.2007E-17 14 122 11 6292
    ribosomal subunit 3.1548E-15 14 183 11 6292
    ribonucleoprotein complex 8.1265E-14 14 514 13 6292
    cytosol 4.2325E-13 14 284 11 6292
    ribosome 5.3342E-13 14 290 11 6292
    cytosolic large ribosomal subunit 1.6483E-9 14 60 6 6292
    cytosolic small ribosomal subunit 1.1774E-8 14 38 5 6292
    large ribosomal subunit 6.674E-8 14 110 6 6292
    non-membrane-bounded organelle 2.2878E-7 14 959 11 6292
    intracellular non-membrane-bounded organelle 2.2878E-7 14 959 11 6292
    macromolecular complex 2.5299E-7 14 1635 13 6292
    small ribosomal subunit 3.3783E-7 14 73 5 6292
    90S preribosome 5.8562E-6 14 17 3 6292
    preribosome 5.0397E-5 14 34 3 6292
    organelle part 1.5376E-3 14 2282 11 6292
    intracellular organelle part 1.5376E-3 14 2282 11 6292
    cytoplasmic part 3.4004E-3 14 2482 11 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 5.8814E-18 14 376 14 6292
    cellular protein metabolic process 1.6609E-11 14 1074 14 6292
    protein metabolic process 3.6611E-11 14 1136 14 6292
    cellular macromolecule biosynthetic process 6.7941E-11 14 1187 14 6292
    macromolecule biosynthetic process 6.957E-11 14 1189 14 6292
    gene expression 2.03E-10 14 1283 14 6292
    cellular biosynthetic process 3.38E-9 14 1567 14 6292
    biosynthetic process 4.6108E-9 14 1602 14 6292
    ribosomal subunit assembly 7.9952E-8 14 55 5 6292
    ribosome assembly 1.7335E-7 14 64 5 6292
    ribosomal small subunit biogenesis 2.2303E-7 14 26 4 6292
    organelle assembly 2.5399E-7 14 69 5 6292
    cellular macromolecule metabolic process 6.7658E-7 14 2285 14 6292
    macromolecule metabolic process 9.9712E-7 14 2349 14 6292
    ribonucleoprotein complex assembly 1.0811E-6 14 92 5 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.476E-6 14 13 3 6292
    ribosomal small subunit assembly 3.1472E-6 14 14 3 6292
    ribosome biogenesis 3.514E-6 14 346 7 6292
    regulation of translation 5.6643E-6 14 57 4 6292
    ribonucleoprotein complex biogenesis 5.9152E-6 14 374 7 6292
    maturation of SSU-rRNA 6.5097E-6 14 59 4 6292
    posttranscriptional regulation of gene expression 7.4451E-6 14 61 4 6292
    regulation of cellular protein metabolic process 1.1515E-5 14 68 4 6292
    regulation of protein metabolic process 1.6145E-5 14 74 4 6292
    primary metabolic process 1.8826E-5 14 2896 14 6292
    cellular macromolecular complex assembly 3.104E-5 14 182 5 6292
    cellular metabolic process 3.6009E-5 14 3033 14 6292
    metabolic process 6.3176E-5 14 3157 14 6292
    rRNA processing 1.3967E-4 14 128 4 6292
    cellular macromolecular complex subunit organization 1.6767E-4 14 259 5 6292
    rRNA metabolic process 1.8175E-4 14 137 4 6292
    macromolecular complex assembly 2.461E-4 14 281 5 6292
    cellular component biogenesis 3.294E-4 14 694 7 6292
    macromolecular complex subunit organization 7.4743E-4 14 357 5 6292
    ncRNA processing 1.0131E-3 14 215 4 6292
    cellular component assembly 1.0553E-3 14 385 5 6292
    ncRNA metabolic process 1.9678E-3 14 257 4 6292
    ribosomal large subunit assembly 3.5879E-3 14 41 2 6292
    cellular process 7.2188E-3 14 4426 14 6292
    RNA processing 8.0733E-3 14 380 4 6292
    ribosomal large subunit biogenesis 8.8278E-3 14 65 2 6292
    maturation of 5.8S rRNA 8.8726E-3 14 4 1 6292
    cleavage involved in rRNA processing 8.8726E-3 14 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.8726E-3 14 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 8.8726E-3 14 4 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.5902E-21 14 212 14 6292
    structural molecule activity 1.3424E-18 14 339 14 6292
    rRNA binding 4.8291E-6 14 16 3 6292
    RNA binding 5.2139E-6 14 367 7 6292
    nucleic acid binding 2.5404E-4 14 666 7 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle