YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 17 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL16A
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL17B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL30
  • cytoplasm
  • negative regulation of nuclear mRNA splicing, via spliceosome
  • rRNA processing
  • negative regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS22A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 8.6832E-19 17 101 12 6292
    cytosolic part 9.3082E-18 17 122 12 6292
    ribosomal subunit 1.3956E-15 17 183 12 6292
    ribonucleoprotein complex 2.6981E-13 17 514 14 6292
    cytosol 2.8811E-13 17 284 12 6292
    ribosome 3.704E-13 17 290 12 6292
    cytosolic large ribosomal subunit 9.5956E-13 17 60 8 6292
    large ribosomal subunit 1.4408E-10 17 110 8 6292
    non-membrane-bounded organelle 4.3408E-7 17 959 12 6292
    intracellular non-membrane-bounded organelle 4.3408E-7 17 959 12 6292
    macromolecular complex 1.8283E-6 17 1635 14 6292
    cytosolic small ribosomal subunit 2.5452E-6 17 38 4 6292
    90S preribosome 1.0886E-5 17 17 3 6292
    small ribosomal subunit 3.5411E-5 17 73 4 6292
    preribosome 9.3109E-5 17 34 3 6292
    organelle part 4.1965E-3 17 2282 12 6292
    intracellular organelle part 4.1965E-3 17 2282 12 6292
    cytoplasmic part 9.2429E-3 17 2482 12 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.1188E-21 17 376 17 6292
    cellular protein metabolic process 7.9759E-14 17 1074 17 6292
    protein metabolic process 2.0853E-13 17 1136 17 6292
    cellular macromolecule biosynthetic process 4.4224E-13 17 1187 17 6292
    macromolecule biosynthetic process 4.5517E-13 17 1189 17 6292
    gene expression 1.6734E-12 17 1283 17 6292
    cellular biosynthetic process 5.109E-11 17 1567 17 6292
    biosynthetic process 7.4517E-11 17 1602 17 6292
    cellular macromolecule metabolic process 3.1999E-8 17 2285 17 6292
    macromolecule metabolic process 5.1262E-8 17 2349 17 6292
    regulation of translation 2.9064E-7 17 57 5 6292
    posttranscriptional regulation of gene expression 4.1032E-7 17 61 5 6292
    regulation of cellular protein metabolic process 7.1095E-7 17 68 5 6292
    regulation of protein metabolic process 1.0882E-6 17 74 5 6292
    primary metabolic process 1.8202E-6 17 2896 17 6292
    cellular metabolic process 4.0023E-6 17 3033 17 6292
    metabolic process 7.9234E-6 17 3157 17 6292
    ribosomal subunit assembly 1.1433E-5 17 55 4 6292
    ribosome assembly 2.0983E-5 17 64 4 6292
    organelle assembly 2.8313E-5 17 69 4 6292
    ribonucleoprotein complex assembly 8.8077E-5 17 92 4 6292
    ribosome biogenesis 1.9529E-4 17 346 6 6292
    ribonucleoprotein complex biogenesis 2.9917E-4 17 374 6 6292
    rRNA processing 3.167E-4 17 128 4 6292
    rRNA metabolic process 4.1071E-4 17 137 4 6292
    maturation of SSU-rRNA 4.8512E-4 17 59 3 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.2669E-4 17 13 2 6292
    ribosomal small subunit assembly 6.135E-4 17 14 2 6292
    cellular macromolecular complex assembly 1.1997E-3 17 182 4 6292
    ribosomal small subunit biogenesis 2.1497E-3 17 26 2 6292
    ncRNA processing 2.222E-3 17 215 4 6292
    cellular process 2.5051E-3 17 4426 17 6292
    response to cycloalkane 2.7018E-3 17 1 1 6292
    response to organic cyclic substance 2.7018E-3 17 1 1 6292
    negative regulation of mRNA processing 2.7018E-3 17 1 1 6292
    negative regulation of nuclear mRNA splicing, via spliceosome 2.7018E-3 17 1 1 6292
    negative regulation of RNA splicing 2.7018E-3 17 1 1 6292
    response to cycloheximide 2.7018E-3 17 1 1 6292
    ncRNA metabolic process 4.2474E-3 17 257 4 6292
    cellular macromolecular complex subunit organization 4.3673E-3 17 259 4 6292
    regulation of gene expression 5.2502E-3 17 445 5 6292
    ribosomal large subunit assembly 5.2962E-3 17 41 2 6292
    regulation of mRNA processing 5.3968E-3 17 2 1 6292
    regulation of RNA splicing 5.3968E-3 17 2 1 6292
    regulation of nuclear mRNA splicing, via spliceosome 5.3968E-3 17 2 1 6292
    regulation of macromolecule biosynthetic process 5.8282E-3 17 456 5 6292
    macromolecular complex assembly 5.8421E-3 17 281 4 6292
    regulation of cellular biosynthetic process 6.749E-3 17 472 5 6292
    regulation of biosynthetic process 6.8098E-3 17 473 5 6292
    cellular component biogenesis 7.4875E-3 17 694 6 6292
    regulation of macromolecule metabolic process 7.7699E-3 17 488 5 6292
    response to antibiotic 8.0849E-3 17 3 1 6292
    regulation of primary metabolic process 9.6568E-3 17 514 5 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 4.9155E-26 17 212 17 6292
    structural molecule activity 1.8461E-22 17 339 17 6292
    RNA binding 2.6984E-4 17 367 6 6292
    rRNA binding 8.0644E-4 17 16 2 6292
    nucleic acid binding 6.1125E-3 17 666 6 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle