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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 18 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL16B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL17B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS3
  • preribosome, small subunit precursor
  • response to DNA damage stimulus
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.7045E-20 18 101 13 6292
    cytosolic part 2.2581E-19 18 122 13 6292
    ribosomal subunit 5.2615E-17 18 183 13 6292
    cytosolic large ribosomal subunit 1.1699E-16 18 60 10 6292
    ribonucleoprotein complex 4.1489E-16 18 514 16 6292
    cytosol 1.7269E-14 18 284 13 6292
    ribosome 2.2691E-14 18 290 13 6292
    large ribosomal subunit 6.8634E-14 18 110 10 6292
    macromolecular complex 3.5912E-8 18 1635 16 6292
    non-membrane-bounded organelle 9.0245E-8 18 959 13 6292
    intracellular non-membrane-bounded organelle 9.0245E-8 18 959 13 6292
    preribosome 2.0618E-6 18 34 4 6292
    90S preribosome 1.3041E-5 18 17 3 6292
    cytosolic small ribosomal subunit 1.5581E-4 18 38 3 6292
    small ribosomal subunit 1.079E-3 18 73 3 6292
    organelle part 2.0665E-3 18 2282 13 6292
    intracellular organelle part 2.0665E-3 18 2282 13 6292
    cytoplasmic part 4.9394E-3 18 2482 13 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 6.4007E-23 18 376 18 6292
    cellular protein metabolic process 1.3435E-14 18 1074 18 6292
    protein metabolic process 3.7187E-14 18 1136 18 6292
    cellular macromolecule biosynthetic process 8.2458E-14 18 1187 18 6292
    macromolecule biosynthetic process 8.5013E-14 18 1189 18 6292
    gene expression 3.3762E-13 18 1283 18 6292
    cellular biosynthetic process 1.262E-11 18 1567 18 6292
    biosynthetic process 1.8822E-11 18 1602 18 6292
    cellular macromolecule metabolic process 1.1566E-8 18 2285 18 6292
    macromolecule metabolic process 1.9051E-8 18 2349 18 6292
    primary metabolic process 8.3514E-7 18 2896 18 6292
    cellular metabolic process 1.9237E-6 18 3033 18 6292
    metabolic process 3.9649E-6 18 3157 18 6292
    ribosomal subunit assembly 1.4604E-5 18 55 4 6292
    regulation of translation 1.6854E-5 18 57 4 6292
    posttranscriptional regulation of gene expression 2.2107E-5 18 61 4 6292
    ribosome assembly 2.6773E-5 18 64 4 6292
    regulation of cellular protein metabolic process 3.4071E-5 18 68 4 6292
    organelle assembly 3.6103E-5 18 69 4 6292
    regulation of protein metabolic process 4.7624E-5 18 74 4 6292
    ribonucleoprotein complex assembly 1.1198E-4 18 92 4 6292
    ribosomal large subunit assembly 1.9583E-4 18 41 3 6292
    ribosomal large subunit biogenesis 7.6868E-4 18 65 3 6292
    cellular macromolecular complex assembly 1.5079E-3 18 182 4 6292
    cellular process 1.7601E-3 18 4426 18 6292
    ribosome biogenesis 2.3083E-3 18 346 5 6292
    response to cycloheximide 2.8608E-3 18 1 1 6292
    response to cycloalkane 2.8608E-3 18 1 1 6292
    response to organic cyclic substance 2.8608E-3 18 1 1 6292
    ribonucleoprotein complex biogenesis 3.2481E-3 18 374 5 6292
    cellular macromolecular complex subunit organization 5.436E-3 18 259 4 6292
    macromolecular complex assembly 7.2516E-3 18 281 4 6292
    response to antibiotic 8.5592E-3 18 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.5275E-27 18 212 18 6292
    structural molecule activity 9.4732E-24 18 339 18 6292
    RNA binding 2.9908E-3 18 367 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle