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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 20 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL16B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL17B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL1A, RPL1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • RNA processing
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL29
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL30
  • cytoplasm
  • negative regulation of nuclear mRNA splicing, via spliceosome
  • rRNA processing
  • negative regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL9A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS22A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.0671E-21 20 101 14 6292
    cytosolic part 1.7453E-20 20 122 14 6292
    cytosolic large ribosomal subunit 2.0942E-20 20 60 12 6292
    ribosomal subunit 6.2828E-18 20 183 14 6292
    large ribosomal subunit 4.9601E-17 20 110 12 6292
    cytosol 3.2354E-15 20 284 14 6292
    ribosome 4.341E-15 20 290 14 6292
    ribonucleoprotein complex 1.125E-14 20 514 16 6292
    non-membrane-bounded organelle 5.2702E-8 20 959 14 6292
    intracellular non-membrane-bounded organelle 5.2702E-8 20 959 14 6292
    macromolecular complex 6.5307E-7 20 1635 16 6292
    organelle part 2.2217E-3 20 2282 14 6292
    intracellular organelle part 2.2217E-3 20 2282 14 6292
    cytoplasmic part 5.5174E-3 20 2482 14 6292
    cytosolic small ribosomal subunit 6.3014E-3 20 38 2 6292
    cytoplasm 6.983E-3 20 3552 17 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 2.0785E-25 20 376 20 6292
    cellular protein metabolic process 3.8031E-16 20 1074 20 6292
    protein metabolic process 1.18E-15 20 1136 20 6292
    cellular macromolecule biosynthetic process 2.8607E-15 20 1187 20 6292
    macromolecule biosynthetic process 2.9594E-15 20 1189 20 6292
    gene expression 1.3717E-14 20 1283 20 6292
    cellular biosynthetic process 7.6887E-13 20 1567 20 6292
    biosynthetic process 1.1992E-12 20 1602 20 6292
    cellular macromolecule metabolic process 1.5096E-9 20 2285 20 6292
    macromolecule metabolic process 2.629E-9 20 2349 20 6292
    primary metabolic process 1.757E-7 20 2896 20 6292
    cellular metabolic process 4.4416E-7 20 3033 20 6292
    regulation of translation 7.1326E-7 20 57 5 6292
    metabolic process 9.9232E-7 20 3157 20 6292
    posttranscriptional regulation of gene expression 1.0054E-6 20 61 5 6292
    regulation of cellular protein metabolic process 1.7371E-6 20 68 5 6292
    regulation of protein metabolic process 2.6524E-6 20 74 5 6292
    ribosomal subunit assembly 2.2825E-5 20 55 4 6292
    ribosome assembly 4.1747E-5 20 64 4 6292
    organelle assembly 5.6224E-5 20 69 4 6292
    ribonucleoprotein complex assembly 1.7337E-4 20 92 4 6292
    ribosomal large subunit assembly 2.7112E-4 20 41 3 6292
    cellular process 8.6878E-4 20 4426 20 6292
    ribosomal large subunit biogenesis 1.0582E-3 20 65 3 6292
    cellular macromolecular complex assembly 2.2819E-3 20 182 4 6292
    response to cycloalkane 3.1786E-3 20 1 1 6292
    response to organic cyclic substance 3.1786E-3 20 1 1 6292
    negative regulation of mRNA processing 3.1786E-3 20 1 1 6292
    negative regulation of nuclear mRNA splicing, via spliceosome 3.1786E-3 20 1 1 6292
    negative regulation of RNA splicing 3.1786E-3 20 1 1 6292
    response to cycloheximide 3.1786E-3 20 1 1 6292
    ribosome biogenesis 3.8143E-3 20 346 5 6292
    ribonucleoprotein complex biogenesis 5.3273E-3 20 374 5 6292
    regulation of mRNA processing 6.3477E-3 20 2 1 6292
    regulation of RNA splicing 6.3477E-3 20 2 1 6292
    regulation of nuclear mRNA splicing, via spliceosome 6.3477E-3 20 2 1 6292
    cellular macromolecular complex subunit organization 8.0681E-3 20 259 4 6292
    response to antibiotic 9.5071E-3 20 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.4532E-30 20 212 20 6292
    structural molecule activity 2.4725E-26 20 339 20 6292
    RNA binding 7.2769E-4 20 367 6 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle