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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 18 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL16B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL17B
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL21A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL29
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL32
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL36A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL8B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • translation
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS26A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS30B, RPS30A
  • stress granule
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 3.2381E-25 18 101 15 6292
    cytosolic part 6.6372E-24 18 122 15 6292
    ribosomal subunit 3.8435E-21 18 183 15 6292
    cytosolic large ribosomal subunit 6.8253E-19 18 60 11 6292
    cytosol 3.312E-18 18 284 15 6292
    ribosome 4.5552E-18 18 290 15 6292
    large ribosomal subunit 8.0638E-16 18 110 11 6292
    ribonucleoprotein complex 2.5769E-14 18 514 15 6292
    non-membrane-bounded organelle 2.6224E-10 18 959 15 6292
    intracellular non-membrane-bounded organelle 2.6224E-10 18 959 15 6292
    macromolecular complex 5.6423E-7 18 1635 15 6292
    cytosolic small ribosomal subunit 3.2583E-6 18 38 4 6292
    small ribosomal subunit 4.513E-5 18 73 4 6292
    organelle part 5.682E-5 18 2282 15 6292
    intracellular organelle part 5.682E-5 18 2282 15 6292
    cytoplasmic part 1.7523E-4 18 2482 15 6292
    cytoplasm 4.9756E-4 18 3552 17 6292
    stress granule 2.8608E-3 18 1 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 6.4007E-23 18 376 18 6292
    cellular protein metabolic process 1.3435E-14 18 1074 18 6292
    protein metabolic process 3.7187E-14 18 1136 18 6292
    cellular macromolecule biosynthetic process 8.2458E-14 18 1187 18 6292
    macromolecule biosynthetic process 8.5013E-14 18 1189 18 6292
    gene expression 3.3762E-13 18 1283 18 6292
    cellular biosynthetic process 1.262E-11 18 1567 18 6292
    biosynthetic process 1.8822E-11 18 1602 18 6292
    cellular macromolecule metabolic process 1.1566E-8 18 2285 18 6292
    macromolecule metabolic process 1.9051E-8 18 2349 18 6292
    primary metabolic process 8.3514E-7 18 2896 18 6292
    cellular metabolic process 1.9237E-6 18 3033 18 6292
    metabolic process 3.9649E-6 18 3157 18 6292
    ribosomal subunit assembly 4.7003E-4 18 55 3 6292
    ribosome assembly 7.3452E-4 18 64 3 6292
    organelle assembly 9.1545E-4 18 69 3 6292
    cellular process 1.7601E-3 18 4426 18 6292
    ribonucleoprotein complex assembly 2.1056E-3 18 92 3 6292
    ribosomal small subunit biogenesis 2.4123E-3 18 26 2 6292
    response to cycloheximide 2.8608E-3 18 1 1 6292
    response to cycloalkane 2.8608E-3 18 1 1 6292
    response to organic cyclic substance 2.8608E-3 18 1 1 6292
    ribosomal large subunit assembly 5.9338E-3 18 41 2 6292
    response to antibiotic 8.5592E-3 18 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.5275E-27 18 212 18 6292
    structural molecule activity 9.4732E-24 18 339 18 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle