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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
IMD4
  • cytoplasm
  • biological_process
  • IMP dehydrogenase activity
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS24A, RPS24B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • mitochondrion
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • nucleotide binding
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 5.2025E-8 8 101 5 6292
    cytosolic small ribosomal subunit 7.7836E-8 8 38 4 6292
    cytosolic part 1.35E-7 8 122 5 6292
    90S preribosome 9.1004E-7 8 17 3 6292
    ribosomal subunit 1.0284E-6 8 183 5 6292
    small ribosomal subunit 1.1273E-6 8 73 4 6292
    preribosome 7.9274E-6 8 34 3 6292
    cytosol 9.0595E-6 8 284 5 6292
    ribosome 1.004E-5 8 290 5 6292
    ribonucleoprotein complex 1.6235E-4 8 514 5 6292
    non-membrane-bounded organelle 2.6233E-4 8 959 6 6292
    intracellular non-membrane-bounded organelle 2.6233E-4 8 959 6 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8367E-7 8 13 3 6292
    regulation of translation 4.125E-7 8 57 4 6292
    posttranscriptional regulation of gene expression 5.4385E-7 8 61 4 6292
    regulation of cellular protein metabolic process 8.4567E-7 8 68 4 6292
    translation 1.1072E-6 8 376 6 6292
    regulation of protein metabolic process 1.1912E-6 8 74 4 6292
    ribosome biogenesis 2.3852E-5 8 346 5 6292
    ribonucleoprotein complex biogenesis 3.4865E-5 8 374 5 6292
    maturation of SSU-rRNA 4.2427E-5 8 59 3 6292
    rRNA processing 4.2742E-4 8 128 3 6292
    cellular protein metabolic process 4.9998E-4 8 1074 6 6292
    rRNA metabolic process 5.2205E-4 8 137 3 6292
    cellular component biogenesis 6.7771E-4 8 694 5 6292
    protein metabolic process 6.8696E-4 8 1136 6 6292
    cellular macromolecule biosynthetic process 8.7999E-4 8 1187 6 6292
    macromolecule biosynthetic process 8.8836E-4 8 1189 6 6292
    gene expression 1.3613E-3 8 1283 6 6292
    regulation of gene expression 1.374E-3 8 445 4 6292
    regulation of macromolecule biosynthetic process 1.5066E-3 8 456 4 6292
    regulation of cellular biosynthetic process 1.7154E-3 8 472 4 6292
    regulation of biosynthetic process 1.7291E-3 8 473 4 6292
    ncRNA processing 1.9402E-3 8 215 3 6292
    regulation of macromolecule metabolic process 1.9441E-3 8 488 4 6292
    regulation of primary metabolic process 2.361E-3 8 514 4 6292
    regulation of cellular metabolic process 2.7603E-3 8 536 4 6292
    regulation of metabolic process 2.9768E-3 8 547 4 6292
    ncRNA metabolic process 3.2376E-3 8 257 3 6292
    cellular biosynthetic process 4.1159E-3 8 1567 6 6292
    biosynthetic process 4.6438E-3 8 1602 6 6292
    RNA processing 9.7426E-3 8 380 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 3.6119E-8 8 212 6 6292
    structural molecule activity 5.984E-7 8 339 6 6292
    rRNA binding 1.6826E-4 8 16 2 6292
    IMP dehydrogenase activity 3.8101E-3 8 3 1 6292
    RNA binding 8.8446E-3 8 367 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle