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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 15 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
IMG1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • IMG2
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • MHR1
  • nucleus
  • mitochondrion
  • mitochondrial genome maintenance
  • transcription regulator activity
  • MRP7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • MRPL1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPL16
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • MRPL17
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL24
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL28
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL35
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL36
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL39
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL4
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL44
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • MRPL7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    organellar large ribosomal subunit 8.1198E-30 15 50 14 6292
    mitochondrial large ribosomal subunit 8.1198E-30 15 50 14 6292
    organellar ribosome 7.7788E-26 15 90 14 6292
    mitochondrial ribosome 7.7788E-26 15 90 14 6292
    large ribosomal subunit 1.5763E-24 15 110 14 6292
    mitochondrial matrix 1.5682E-21 15 176 14 6292
    mitochondrial lumen 1.5682E-21 15 176 14 6292
    ribosomal subunit 2.7614E-21 15 183 14 6292
    ribosome 2.0714E-18 15 290 14 6292
    mitochondrial part 2.2814E-15 15 475 14 6292
    ribonucleoprotein complex 6.9455E-15 15 514 14 6292
    organelle lumen 2.3378E-13 15 660 14 6292
    intracellular organelle lumen 2.3378E-13 15 660 14 6292
    membrane-enclosed lumen 5.3354E-13 15 700 14 6292
    mitochondrion 5.6494E-12 15 1125 15 6292
    non-membrane-bounded organelle 4.3415E-11 15 959 14 6292
    intracellular non-membrane-bounded organelle 4.3415E-11 15 959 14 6292
    macromolecular complex 6.9919E-8 15 1635 14 6292
    cytoplasmic part 8.4926E-7 15 2482 15 6292
    organelle part 6.6039E-6 15 2282 14 6292
    intracellular organelle part 6.6039E-6 15 2282 14 6292
    cytoplasm 1.8606E-4 15 3552 15 6292
    membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    intracellular membrane-bounded organelle 4.5726E-4 15 3771 15 6292
    intracellular organelle 1.4392E-3 15 4070 15 6292
    organelle 1.4445E-3 15 4071 15 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 8.3474E-17 15 376 14 6292
    cellular protein metabolic process 2.0988E-10 15 1074 14 6292
    protein metabolic process 4.5756E-10 15 1136 14 6292
    cellular macromolecule biosynthetic process 8.414E-10 15 1187 14 6292
    macromolecule biosynthetic process 8.6126E-10 15 1189 14 6292
    gene expression 2.4706E-9 15 1283 14 6292
    cellular biosynthetic process 3.8994E-8 15 1567 14 6292
    biosynthetic process 5.2834E-8 15 1602 14 6292
    cellular macromolecule metabolic process 6.7223E-6 15 2285 14 6292
    macromolecule metabolic process 9.7648E-6 15 2349 14 6292
    primary metabolic process 1.614E-4 15 2896 14 6292
    cellular metabolic process 2.9771E-4 15 3033 14 6292
    metabolic process 5.0484E-4 15 3157 14 6292
    cellular process 5.0732E-3 15 4426 15 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 2.315E-20 15 212 14 6292
    structural molecule activity 1.9163E-17 15 339 14 6292
    peptidyltransferase activity 1.5894E-5 15 3 2 6292
    transferase activity, transferring amino-acyl groups 5.2834E-5 15 5 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle