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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 18 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
IMG1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • IMG2
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • MHR1
  • nucleus
  • mitochondrion
  • mitochondrial genome maintenance
  • transcription regulator activity
  • MRP49
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRP7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • MRPL1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPL13
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL16
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • MRPL17
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL20
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial genome maintenance
  • translation
  • structural constituent of ribosome
  • MRPL24
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL28
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL35
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL36
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL4
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL8
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial genome maintenance
  • translation
  • structural constituent of ribosome
  • YML6
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    organellar large ribosomal subunit 1.6884E-36 18 50 17 6292
    mitochondrial large ribosomal subunit 1.6884E-36 18 50 17 6292
    organellar ribosome 1.5925E-31 18 90 17 6292
    mitochondrial ribosome 1.5925E-31 18 90 17 6292
    large ribosomal subunit 6.5585E-30 18 110 17 6292
    mitochondrial matrix 3.1758E-26 18 176 17 6292
    mitochondrial lumen 3.1758E-26 18 176 17 6292
    ribosomal subunit 6.3536E-26 18 183 17 6292
    ribosome 2.0901E-22 18 290 17 6292
    mitochondrial part 1.077E-18 18 475 17 6292
    ribonucleoprotein complex 4.1851E-18 18 514 17 6292
    organelle lumen 3.0413E-16 18 660 17 6292
    intracellular organelle lumen 3.0413E-16 18 660 17 6292
    membrane-enclosed lumen 8.3132E-16 18 700 17 6292
    mitochondrion 3.1171E-14 18 1125 18 6292
    non-membrane-bounded organelle 1.7694E-13 18 959 17 6292
    intracellular non-membrane-bounded organelle 1.7694E-13 18 959 17 6292
    macromolecular complex 1.4375E-9 18 1635 17 6292
    cytoplasmic part 5.1519E-8 18 2482 18 6292
    organelle part 3.7122E-7 18 2282 17 6292
    intracellular organelle part 3.7122E-7 18 2282 17 6292
    cytoplasm 3.3277E-5 18 3552 18 6292
    membrane-bounded organelle 9.7936E-5 18 3771 18 6292
    intracellular membrane-bounded organelle 9.7936E-5 18 3771 18 6292
    intracellular organelle 3.879E-4 18 4070 18 6292
    organelle 3.8963E-4 18 4071 18 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.905E-20 18 376 17 6292
    cellular protein metabolic process 1.2073E-12 18 1074 17 6292
    protein metabolic process 3.1214E-12 18 1136 17 6292
    cellular macromolecule biosynthetic process 6.5585E-12 18 1187 17 6292
    macromolecule biosynthetic process 6.7478E-12 18 1189 17 6292
    gene expression 2.4382E-11 18 1283 17 6292
    cellular biosynthetic process 7.0508E-10 18 1567 17 6292
    biosynthetic process 1.0213E-9 18 1602 17 6292
    cellular macromolecule metabolic process 3.7937E-7 18 2285 17 6292
    macromolecule metabolic process 5.9885E-7 18 2349 17 6292
    primary metabolic process 1.8567E-5 18 2896 17 6292
    cellular metabolic process 3.9339E-5 18 3033 17 6292
    metabolic process 7.5219E-5 18 3157 17 6292
    mitochondrial genome maintenance 1.1132E-4 18 34 3 6292
    cellular process 1.7601E-3 18 4426 18 6292
    mitochondrion organization 9.2792E-3 18 156 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 8.5883E-25 18 212 17 6292
    structural molecule activity 3.1619E-21 18 339 17 6292
    peptidyltransferase activity 2.3152E-5 18 3 2 6292
    transferase activity, transferring amino-acyl groups 7.6913E-5 18 5 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle