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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.085] [SVM Score: 0.487911803909]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

rough endoplasmic reticulum 3.3348E-6 2 12 2 6292
rough endoplasmic reticulum membrane 3.3348E-6 2 12 2 6292
endoplasmic reticulum membrane 4.4352E-4 2 133 2 6292
endoplasmic reticulum part 5.6464E-4 2 150 2 6292
subsynaptic reticulum 5.6464E-4 2 150 2 6292
receptor complex 6.3568E-4 2 2 1 6292
signal recognition particle receptor complex 6.3568E-4 2 2 1 6292
nuclear membrane-endoplasmic reticulum network 1.3539E-3 2 232 2 6292
Sec62/Sec63 complex 1.5888E-3 2 5 1 6292
endoplasmic reticulum Sec complex 1.5888E-3 2 5 1 6292
endoplasmic reticulum 3.3381E-3 2 364 2 6292
endomembrane system 3.9918E-3 2 398 2 6292
integral to endoplasmic reticulum membrane 9.8303E-3 2 31 1 6292
intrinsic to endoplasmic reticulum membrane 9.8303E-3 2 31 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein targeting to ER 2.6678E-5 2 33 2 6292
protein localization in endoplasmic reticulum 3.9411E-5 2 40 2 6292
protein targeting to membrane 6.6999E-5 2 52 2 6292
protein localization in organelle 5.5711E-4 2 149 2 6292
protein targeting 1.3892E-3 2 235 2 6292
intracellular protein transport 1.6363E-3 2 255 2 6292
protein transport 1.8213E-3 2 269 2 6292
establishment of protein localization 1.8485E-3 2 271 2 6292
cellular protein localization 1.8898E-3 2 274 2 6292
cellular macromolecule localization 2.0305E-3 2 284 2 6292
protein localization 2.3118E-3 2 303 2 6292
posttranslational protein targeting to membrane 2.859E-3 2 9 1 6292
macromolecule localization 3.9717E-3 2 397 2 6292
SRP-dependent cotranslational protein targeting to membrane 6.6645E-3 2 21 1 6292
cotranslational protein targeting to membrane 7.6148E-3 2 24 1 6292
intracellular transport 7.7118E-3 2 553 2 6292
establishment of localization in cell 9.0494E-3 2 599 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

signal recognition particle binding 6.3568E-4 2 2 1 6292
ribonucleoprotein binding 2.224E-3 2 7 1 6292
guanyl ribonucleotide binding 5.0798E-3 2 16 1 6292
GTP binding 5.0798E-3 2 16 1 6292
guanyl nucleotide binding 5.7138E-3 2 18 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle