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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.496823844193]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
COX15
  • mitochondrion
  • mitochondrial inner membrane
    		•
  • heme a biosynthetic process
    		•
  • oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor
    		•
    HEM15
  • mitochondrion
  • mitochondrial inner membrane
    		•
  • heme biosynthetic process
    		•
  • ferrochelatase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mitochondrial inner membrane 7.6048E-4 2 174 2 6292
    organelle inner membrane 8.5997E-4 2 185 2 6292
    mitochondrial membrane 1.7808E-3 2 266 2 6292
    mitochondrial envelope 2.4514E-3 2 312 2 6292
    mitochondrial part 5.6881E-3 2 475 2 6292
    organelle envelope 6.43E-3 2 505 2 6292
    envelope 6.43E-3 2 505 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    heme biosynthetic process 3.9411E-6 2 13 2 6292
    porphyrin biosynthetic process 3.9411E-6 2 13 2 6292
    tetrapyrrole biosynthetic process 3.9411E-6 2 13 2 6292
    heme metabolic process 5.3053E-6 2 15 2 6292
    porphyrin metabolic process 5.3053E-6 2 15 2 6292
    tetrapyrrole metabolic process 5.3053E-6 2 15 2 6292
    pigment biosynthetic process 9.6001E-6 2 20 2 6292
    pigment metabolic process 1.1672E-5 2 22 2 6292
    heterocycle biosynthetic process 1.2202E-4 2 70 2 6292
    cofactor biosynthetic process 1.5966E-4 2 80 2 6292
    cofactor metabolic process 5.9526E-4 2 154 2 6292
    heterocycle metabolic process 7.3441E-4 2 171 2 6292
    heme a biosynthetic process 9.5344E-4 2 3 1 6292
    heme a metabolic process 9.5344E-4 2 3 1 6292
    cellular nitrogen compound biosynthetic process 1.5351E-3 2 247 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ferrochelatase activity 6.3568E-4 2 2 1 6292
    oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor 1.5888E-3 2 5 1 6292
    oxidoreductase activity, acting on NADH or NADPH 6.6645E-3 2 21 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle