YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.632933669151]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
CDC53
  • SCF ubiquitin ligase complex
    		•
  • G2/M transition of mitotic cell cycle
  • G1/S transition of mitotic cell cycle
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  • protein ubiquitination during ubiquitin-dependent protein catabolic process
    		•
  • DNA replication origin binding
  • ubiquitin-protein ligase activity
  • protein binding, bridging
    		•
    DIA2
  • SCF ubiquitin ligase complex
    		•
  • DNA replication
  • invasive growth in response to glucose limitation
  • protein ubiquitination
    		•
  • DNA replication origin binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    SCF ubiquitin ligase complex 2.779E-6 2 11 2 6292
    cullin-RING ubiquitin ligase complex 4.5979E-6 2 14 2 6292
    ubiquitin ligase complex 4.5626E-5 2 43 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein ubiquitination 1.051E-4 2 65 2 6292
    protein modification by small protein conjugation 1.8468E-4 2 86 2 6292
    protein modification by small protein conjugation or removal 3.2544E-4 2 114 2 6292
    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2.224E-3 2 7 1 6292
    post-translational protein modification 3.2108E-3 2 357 2 6292
    protein ubiquitination during ubiquitin-dependent protein catabolic process 3.4937E-3 2 11 1 6292
    protein modification process 6.278E-3 2 499 2 6292
    macromolecule modification 8.1649E-3 2 569 2 6292
    G2/M transition of mitotic cell cycle 9.1975E-3 2 29 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA replication origin binding 3.9411E-6 2 13 2 6292
    sequence-specific DNA binding 6.1895E-5 2 50 2 6292
    DNA binding 1.6492E-3 2 256 2 6292
    protein binding, bridging 6.3477E-3 2 20 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle