Protein Overview: gi|40849930, gi|...

General Information:
Name(s) found:	gi\|47607492 [NCBI NR] gi\|40849930 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|47607492\|ref\|NP_000436.2\| plectin 1 isoform 1c [Homo sapiens] [NCBI NR] gi\|40849930\|gb\|AAR95677.1\| plectin 1 [Homo sapiens] [NCBI NR] plectin 1 isoform 1; hemidesmosomal protein 1; epidermolysis bullosa simplex 1 (Ogna); plectin 1, intermediate filament binding protein, 500kD [071204_hmrz_cont.fasta] plectin 1 isoform 1 [Homo sapiens]gi\|40849930\|gb\|AAR95677.1\| plectin 1 [Homo sapiens] [nrdb_11152004_Chlamydomonas] Tax_Id=9606 plectin 1 isoform 1 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] plectin 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] Tax_Id=9606 Plectin 1 [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta] plectin 1 isoform 1; hemidesmosomal protein 1; epidermolysis bullosa simplex 1 (Ogna); plectin 1, intermediate filament binding protein, 500kD [Homo sapiens] [HumanGallus06162005.fasta] plectin 1 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=PLEC1 Isoform 2 of Plectin-1 [human-ipi-250309-contam.fasta] plectin isoform 1c [Homo sapiens] [NCBI-RefSeq_human_na_10-19-2009_con_reversed.fasta] IPI:IPI00186711.4\|SWISS-PROT:Q15149-2\|ENSEMBL:ENSP00000349868\|REFSEQ:NP_000436\|H-INV:HIT000254874\|VEGA:OTTHUMP00000178422 Tax_Id=9606 Gene_Symbol=PLEC1 Isoform 2 of Plectin-1 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=PLEC1 plectin 1 isoform 1 [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=PLEC Isoform 2 of Plectin-1 [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta] Isoform 2 of Plectin OS=Homo sapiens GN=PLEC [011711_HMR.fasta] IPI:IPI00186711.4\|SWISS-PROT:Q15149-2\|ENSEMBL:ENSP00000349868\|REFSEQ:NP_000436\|H-INV:HIT000254874\|VEGA:OTTHUMP00000178422 Tax_Id=9606 Gene_Symbol=PLEC Isoform 2 of Plectin-1 [ipi.HUMAN.fasta.20100406] GeneSymbol=PLEC Synonyms=EBS1\|EBSO\|HD1\|LGMD2Q\|PCN\|PLEC1\|PLEC1b\|PLTN plectin isoform 1c [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00186711.4\|SWISS-PROT:Q15149-2\|ENSEMBL:ENSP00000388180;ENSP00000444791\|REFSEQ:NP_000436\|H-INV:HIT000254874\|VEGA:OTTHUMP00000229287 Tax_Id=9606 Gene_Symbol=PLEC Isoform 2 of Plectin [ipi.HUMAN.20110912.fasta] Isoform 2 of Plectin GN=PLEC [Doctor+uniprot-HUMAN-120911.fasta] Tax_Id=9606 Gene_Symbol=PLEC Isoform 2 of Plectin [human-ipi-270911-contam-BSA.fasta] IPI:IPI00186711.4\|SWISS-PROT:Q15149-2\|ENSEMBL:ENSP00000388180\|REFSEQ:NP_000436\|H-INV:HIT000254874\|VEGA:OTTHUMP00000229287 Tax_Id=9606 Gene_Symbol=PLEC Isoform 2 of Plectin [ipi.HUMAN.fasta.20110927] Isoform of Q15149, Isoform 2 of Plectin OS=Homo sapiens GN=PLEC [2016-04-human-contam-aPKC-His-Par6.fasta]
Organism:	Homo sapiens
Length:	4574 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGEDAEVRA VSEDVSNGSS GSPSPGDTLP WNLGKTQRSR RSGGGAGSNG SVLDPAERAV  60
   61 IRIADERDRV QKKTFTKWVN KHLIKAQRHI SDLYEDLRDG HNLISLLEVL SGDSLPREKG 120
  121 RMRFHKLQNV QIALDYLRHR QVKLVNIRND DIADGNPKLT LGLIWTIILH FQISDIQVSG 180
  181 QSEDMTAKEK LLLWSQRMVE GYQGLRCDNF TSSWRDGRLF NAIIHRHKPL LIDMNKVYRQ 240
  241 TNLENLDQAF SVAERDLGVT RLLDPEDVDV PQPDEKSIIT YVSSLYDAMP RVPDVQDGVR 300
  301 ANELQLRWQE YRELVLLLLQ WMRHHTAAFE ERRFPSSFEE IEILWSQFLK FKEMELPAKE 360
  361 ADKNRSKGIY QSLEGAVQAG QLKVPPGYHP LDVEKEWGKL HVAILEREKQ LRSEFERLEC 420
  421 LQRIVTKLQM EAGLCEEQLN QADALLQSDV RLLAAGKVPQ RAGEVERDLD KADSMIRLLF 480
  481 NDVQTLKDGR HPQGEQMYRR VYRLHERLVA IRTEYNLRLK AGVAAPATQV AQVTLQSVQR 540
  541 RPELEDSTLR YLQDLLAWVE ENQHRVDGAE WGVDLPSVEA QLGSHRGLHQ SIEEFRAKIE 600
  601 RARSDEGQLS PATRGAYRDC LGRLDLQYAK LLNSSKARLR SLESLHSFVA AATKELMWLN 660
  661 EKEEEEVGFD WSDRNTNMTA KKESYSALMR ELELKEKKIK ELQNAGDRLL REDHPARPTV 720
  721 ESFQAALQTQ WSWMLQLCCC IEAHLKENAA YFQFFSDVRE AEGQLQKLQE ALRRKYSCDR 780
  781 SATVTRLEDL LQDAQDEKEQ LNEYKGHLSG LAKRAKAVVQ LKPRHPAHPM RGRLPLLAVC 840
  841 DYKQVEVTVH KGDECQLVGP AQPSHWKVLS SSGSEAAVPS VCFLVPPPNQ EAQEAVTRLE 900
  901 AQHQALVTLW HQLHVDMKSL LAWQSLRRDV QLIRSWSLAT FRTLKPEEQR QALHSLELHY 960
  961 QAFLRDSQDA GGFGPEDRLM AEREYGSCSH HYQQLLQSLE QGAQEESRCQ RCISELKDIR1020
 1021 LQLEACETRT VHRLRLPLDK EPARECAQRI AEQQKAQAEV EGLGKGVARL SAEAEKVLAL1080
 1081 PEPSPAAPTL RSELELTLGK LEQVRSLSAI YLEKLKTISL VIRGTQGAEE VLRAHEEQLK1140
 1141 EAQAVPATLP ELEATKASLK KLRAQAEAQQ PTFDALRDEL RGAQEVGERL QQRHGERDVE1200
 1201 VERWRERVAQ LLERWQAVLA QTDVRQRELE QLGRQLRYYR ESADPLGAWL QDARRRQEQI1260
 1261 QAMPLADSQA VREQLRQEQA LLEEIERHGE KVEECQRFAK QYINAIKDYE LQLVTYKAQL1320
 1321 EPVASPAKKP KVQSGSESVI QEYVDLRTHY SELTTLTSQY IKFISETLRR MEEEERLAEQ1380
 1381 QRAEERERLA EVEAALEKQR QLAEAHAQAK AQAEREAKEL QQRMQEEVVR REEAAVDAQQ1440
 1441 QKRSIQEELQ QLRQSSEAEI QAKARQAEAA ERSRLRIEEE IRVVRLQLEA TERQRGGAEG1500
 1501 ELQALRARAE EAEAQKRQAQ EEAERLRRQV QDESQRKRQA EVELASRVKA EAEAAREKQR1560
 1561 ALQALEELRL QAEEAERRLR QAEVERARQV QVALETAQRS AEAELQSKRA SFAEKTAQLE1620
 1621 RSLQEEHVAV AQLREEAERR AQQQAEAERA REEAERELER WQLKANEALR LRLQAEEVAQ1680
 1681 QKSLAQAEAE KQKEEAEREA RRRGKAEEQA VRQRELAEQE LEKQRQLAEG TAQQRLAAEQ1740
 1741 ELIRLRAETE QGEQQRQLLE EELARLQREA AAATQKRQEL EAELAKVRAE MEVLLASKAR1800
 1801 AEEESRSTSE KSKQRLEAEA GRFRELAEEA ARLRALAEEA KRQRQLAEED AARQRAEAER1860
 1861 VLAEKLAAIG EATRLKTEAE IALKEKEAEN ERLRRLAEDE AFQRRRLEEQ AAQHKADIEE1920
 1921 RLAQLRKASD SELERQKGLV EDTLRQRRQV EEEILALKAS FEKAAAGKAE LELELGRIRS1980
 1981 NAEDTLRSKE QAELEAARQR QLAAEEERRR REAEERVQKS LAAEEEAARQ RKAALEEVER2040
 2041 LKAKVEEARR LRERAEQESA RQLQLAQEAA QKRLQAEEKA HAFAVQQKEQ ELQQTLQQEQ2100
 2101 SVLDQLRGEA EAARRAAEEA EEARVQAERE AAQSRRQVEE AERLKQSAEE QAQARAQAQA2160
 2161 AAEKLRKEAE QEAARRAQAE QAALRQKQAA DAEMEKHKKF AEQTLRQKAQ VEQELTTLRL2220
 2221 QLEETDHQKN LLDEELQRLK AEATEAARQR SQVEEELFSV RVQMEELSKL KARIEAENRA2280
 2281 LILRDKDNTQ RFLQEEAEKM KQVAEEAARL SVAAQEAARL RQLAEEDLAQ QRALAEKMLK2340
 2341 EKMQAVQEAT RLKAEAELLQ QQKELAQEQA RRLQEDKEQM AQQLAEETQG FQRTLEAERQ2400
 2401 RQLEMSAEAE RLKLRVAEMS RAQARAEEDA QRFRKQAEEI GEKLHRTELA TQEKVTLVQT2460
 2461 LEIQRQQSDH DAERLREAIA ELEREKEKLQ QEAKLLQLKS EEMQTVQQEQ LLQETQALQQ2520
 2521 SFLSEKDSLL QRERFIEQEK AKLEQLFQDE VAKAQQLREE QQRQQQQMEQ ERQRLVASME2580
 2581 EARRRQHEAE EGVRRKQEEL QQLEQQRRQQ EELLAEENQR LREQLQLLEE QHRAALAHSE2640
 2641 EVTASQVAAT KTLPNGRDAL DGPAAEAEPE HSFDGLRRKV SAQRLQEAGI LSAEELQRLA2700
 2701 QGHTTVDELA RREDVRHYLQ GRSSIAGLLL KATNEKLSVY AALQRQLLSP GTALILLEAQ2760
 2761 AASGFLLDPV RNRRLTVNEA VKEGVVGPEL HHKLLSAERA VTGYKDPYTG QQISLFQAMQ2820
 2821 KGLIVREHGI RLLEAQIATG GVIDPVHSHR VPVDVAYRRG YFDEEMNRVL ADPSDDTKGF2880
 2881 FDPNTHENLT YLQLLERCVE DPETGLCLLP LTDKAAKGGE LVYTDSEARD VFEKATVSAP2940
 2941 FGKFQGKTVT IWEIINSEYF TAEQRRDLLR QFRTGRITVE KIIKIIITVV EEQEQKGRLC3000
 3001 FEGLRSLVPA AELLESRVID RELYQQLQRG ERSVRDVAEV DTVRRALRGA NVIAGVWLEE3060
 3061 AGQKLSIYNA LKKDLLPSDM AVALLEAQAG TGHIIDPATS ARLTVDEAVR AGLVGPEFHE3120
 3121 KLLSAEKAVT GYRDPYTGQS VSLFQALKKG LIPREQGLRL LDAQLSTGGI VDPSKSHRVP3180
 3181 LDVACARGCL DEETSRALSA PRADAKAYSD PSTGEPATYG ELQQRCRPDQ LTGLSLLPLS3240
 3241 EKAARARQEE LYSELQARET FEKTPVEVPV GGFKGRTVTV WELISSEYFT AEQRQELLRQ3300
 3301 FRTGKVTVEK VIKILITIVE EVETLRQERL SFSGLRAPVP ASELLASGVL SRAQFEQLKD3360
 3361 GKTTVKDLSE LGSVRTLLQG SGCLAGIYLE DTKEKVSIYE AMRRGLLRAT TAALLLEAQA3420
 3421 ATGFLVDPVR NQRLYVHEAV KAGVVGPELH EQLLSAEKAV TGYRDPYSGS TISLFQAMQK3480
 3481 GLVLRQHGIR LLEAQIATGG IIDPVHSHRV PVDVAYQRGY FSEEMNRVLA DPSDDTKGFF3540
 3541 DPNTHENLTY RQLLERCVED PETGLRLLPL KGAEKAEVVE TTQVYTEEET RRAFEETQID3600
 3601 IPGGGSHGGS TMSLWEVMQS DLIPEEQRAQ LMADFQAGRV TKERMIIIII EIIEKTEIIR3660
 3661 QQGLASYDYV RRRLTAEDLF EARIISLETY NLLREGTRSL REALEAESAW CYLYGTGSVA3720
 3721 GVYLPGSRQT LSIYQALKKG LLSAEVARLL LEAQAATGFL LDPVKGERLT VDEAVRKGLV3780
 3781 GPELHDRLLS AERAVTGYRD PYTEQTISLF QAMKKELIPT EEALRLLDAQ LATGGIVDPR3840
 3841 LGFHLPLEVA YQRGYLNKDT HDQLSEPSEV RSYVDPSTDE RLSYTQLLRR CRRDDGTGQL3900
 3901 LLPLSDARKL TFRGLRKQIT MEELVRSQVM DEATALQLRE GLTSIEEVTK NLQKFLEGTS3960
 3961 CIAGVFVDAT KERLSVYQAM KKGIIRPGTA FELLEAQAAT GYVIDPIKGL KLTVEEAVRM4020
 4021 GIVGPEFKDK LLSAERAVTG YKDPYSGKLI SLFQAMKKGL ILKDHGIRLL EAQIATGGII4080
 4081 DPEESHRLPV EVAYKRGLFD EEMNEILTDP SDDTKGFFDP NTEENLTYLQ LMERCITDPQ4140
 4141 TGLCLLPLKE KKRERKTSSK SSVRKRRVVI VDPETGKEMS VYEAYRKGLI DHQTYLELSE4200
 4201 QECEWEEITI SSSDGVVKSM IIDRRSGRQY DIDDAIAKNL IDRSALDQYR AGTLSITEFA4260
 4261 DMLSGNAGGF RSRSSSVGSS SSYPISPAVS RTQLASWSDP TEETGPVAGI LDTETLEKVS4320
 4321 ITEAMHRNLV DNITGQRLLE AQACTGGIID PSTGERFPVT DAVNKGLVDK IMVDRINLAQ4380
 4381 KAFCGFEDPR TKTKMSAAQA LKKGWLYYEA GQRFLEVQYL TGGLIEPDTP GRVPLDEALQ4440
 4441 RGTVDARTAQ KLRDVGAYSK YLTCPKTKLK ISYKDALDRS MVEEGTGLRL LEAAAQSTKG4500
 4501 YYSPYSVSGS GSTAGSRTGS RTGSRAGSRR GSFDATGSGF SMTFSSSSYS SSGYGRRYAS4560
 4561 GSSASLGGPE SAVA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	None Entered	Sample pIC145 from april 2005	Okada, M., et al. (2006)
View Run	gi\|14317902, gi\|...	No Comments	Cheeseman, I.M., et al. (2004)
View Run	MIS12	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: gi|40849930, gi|...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: