Protein Overview: RAPH1

General Information:
Name(s) found:	RAPH1 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|47132519\|ref\|NP_998754.1\| Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] [NCBI NR] gi\|215274220\|sp\|Q70E73.3\|RAPH1_HUMAN RecName: Full=Ras-associated and pleckstrin homology domains-containing protein 1; Short=RAPH1; AltName: Full=Lamellipodin; AltName: Full=Proline-rich EVH1 ligand 2; Short=PREL-2; AltName: Full=Protein RMO1; AltName: F [NCBI NR] Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [HGNC (HUGO)] Ras-associated and pleckstrin homology domains-containing protein 1 OS=Homo sapiens GN=RAPH1 PE=1 SV=3 [Swiss-Prot] Ras association and pleckstrin homology domains 1 isoform 1; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 9; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 18 [071204_hmrz_cont.fasta] Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] [nrdb_11152004_Chlamydomonas] Ras association and pleckstrin homology domains 1 isoform 1; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 9; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 18 [Homo sapiens] [HumanGallus06162005.fasta] Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 [Homo sapiens] [human-NCBI-042104-rand.fasta] Tax_Id=9606 Gene_Symbol=RAPH1 Isoform RMO1-RAPH1 of Ras-associated and pleckstrin homology domains-containing protein 1 [human-ipi-250309-contam.fasta] IPI:IPI00871620.2\|SWISS-PROT:Q70E73-10\|ENSEMBL:ENSP00000316543\|REFSEQ:NP_998754\|VEGA:OTTHUMP00000163779 Tax_Id=9606 Gene_Symbol=RAPH1 Isoform RMO1-RAPH1 of Ras-associated and pleckstrin homology domains-containing protein 1 [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] ras-associated and pleckstrin homology domains-containing protein 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q70E73;Q96Q37;Q9C0I2; RecName: Full=Ras-associated and pleckstrin homology domains-containing protein 1; AltName: Full=Lamellipodin; AltName: Full=Proline-rich EVH1 ligand 2; AltName: Full=Protein RMO1; AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein; AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Isoform RMO1-RAPH1 of Ras-associated and pleckstrin homology domains-containing protein 1 OS=Homo sapiens GN=RAPH1 [011711_HMR.fasta] GeneSymbol=RAPH1 Synonyms=ALS2CR18\|ALS2CR9\|KIAA1681\|LPD\|PREL2\|RMO1\|RalGDS/AF-6 ras-associated and pleckstrin homology domains-containing protein 1 isoform 1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Ras-associated and pleckstrin homology domains-containing protein 1 GN=RAPH1 [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	1250 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQLSDEEID HGAEEDSDKE DQDLDKMFGA WLGELDKLTQ SLDSDKPMEP VKRSPLRQET  60
   61 NMANFSYRFS IYNLNEALNQ GETVDLDALM ADLCSIEQEL SSIGSGNSKR QITETKATQK 120
  121 LPVSRHTLKH GTLKGLSSSS NRIAKPSHAS YSLDDVTAQL EQASLSMDEA AQQSVLEDTK 180
  181 PLVTNQHRRT ASAGTVSDAE VHSISNSSHS SITSAASSMD SLDIDKVTRP QELDLTHQGQ 240
  241 PITEEEQAAK LKAEKIRVAL EKIKEAQVKK LVIRVHMSDD SSKTMMVDER QTVRQVLDNL 300
  301 MDKSHCGYSL DWSLVETVSE LQMERIFEDH ENLVENLLNW TRDSQNKLIF MERIEKYALF 360
  361 KNPQNYLLGK KETAEMADRN KEVLLEECFC GSSVTVPEIE GVLWLKDDGK KSWKKRYFLL 420
  421 RASGIYYVPK GKAKVSRDLV CFLQLDHVNV YYGQDYRNKY KAPTDYCLVL KHPQIQKKSQ 480
  481 YIKYLCCDDV RTLHQWVNGI RIAKYGKQLY MNYQEALKRT ESAYDWTSLS SSSIKSGSSS 540
  541 SSIPESQSNH SNQSDSGVSD TQPAGHVRSQ SIVSSVFSEA WKRGTQLEES SKARMESMNR 600
  601 PYTSLVPPLS PQPKIVTPYT ASQPSPPLPP PPPPPPPPPP PPPPPPPPLP SQSAPSAGSA 660
  661 APMFVKYSTI TRLQNASQHS GALFKPPTPP VMQSQSVKPQ ILVPPNGVVP PPPPPPPPPT 720
  721 PGSAMAQLKP APCAPSLPQF SAPPPPLKIH QVQHITQVAP PTPPPPPPIP APLPPQAPPK 780
  781 PLVTIPAPTS TKTVAPVVTQ AAPPTPTPPV PPAKKQPAFP ASYIPPSPPT PPVPVPPPTL 840
  841 PKQQSFCAKP PPSPLSPVPS VVKQIASQFP PPPTPPAMES QPLKPVPANV APQSPPAVKA 900
  901 KPKWQPSSIP VPSPDFPPPP PESSLVFPPP PPSPVPAPPP PPPPTASPTP DKSGSPGKKT 960
  961 SKTSSPGGKK PPPTPQRNSS IKSSSGAEHP EPKRPSVDSL VSKFTPPAES GSPSKETLPP1020
 1021 PAAPPKPGKL NLSGVNLPGV LQQGCVSAKA PVLSGRGKDS VVEFPSPPSD SDFPPPPPET1080
 1081 ELPLPPIEIP AVFSGNTSPK VAVVNPQPQQ WSKMSVKKAP PPTRPKRNDS TRLTQAEISE1140
 1141 QPTMATVVPQ VPTSPKSSLS VQPGFLADLN RTLQRKSITR HGSLSSRMSR AEPTATMDDM1200
 1201 ALPPPPPELL SDQQKAGYGG SHISGYATLR RGPPPAPPKR DQNTKLSRDW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	None Entered	Sample pIC145 from april 2005	Okada, M., et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: RAPH1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: