Protein Overview: TOP1M_RAT

General Information:
Name(s) found:	TOP1M_RAT [Swiss-Prot]
Description(s) found: Found 14 descriptions. SHOW ALL	DNA topoisomerase I, mitochondrial OS=Rattus norvegicus GN=Top1mt PE=2 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	593 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [UNKNOWN][IEA] chromosome [IEA] mitochondrial nucleoid [UNKNOWN][IEA]
Biological Process:	DNA topological change [IEA] DNA unwinding involved in replication [IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] DNA topoisomerase type I activity [IEA] DNA topoisomerase (ATP-hydrolyzing) activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLWLRALC RRFQHVPRRV PSRQVSRGSK ASRAGWGETS KSSVKWKQLE HKGPCFAPAY  60
   61 EPLPDGVRFF YDGKPVRLSL AAEEVATFYG KMLHLECTTK EVFRRNFFSD WQKEMTAEER 120
  121 KLITHLDKCD FSEIHRHFME RAEARRTLPR EQKQKLKEEA EKLQQEFGYC ILDGHREKIG 180
  181 NFKTEPPGLF RGRGDHPKMG MLKRRVMPED VVINCSRDSK IPEPPAGHQW KEVRSDNTVM 240
  241 WLAAWVENIQ NSFKYIILNP SSKPKGEMDW QKYEVARRLK GVVDKIRAQY QADWKSPEMK 300
  301 KRQLAVALYF IDKLALRTGN EKEEGETADT VGCCSLRVEH VRLHTPADGQ EHVVELDFLG 360
  361 KDSIRYKNHV TVEKLVFQNL QHFMEDKDPR DDLFDALTTS SLNKHLQDLM EGLTAKVFRT 420
  421 YNASITLQEQ LRVLTRAEDS LTCKVLAYNR ANRAVAVLCN HQRAIPKTFE ESMQTLQKKI 480
  481 ETKKAQVAEA QVELQKAETD LRMRGDSKSK SFLQKQQRLL KLEEQLARLC TKATDKEENK 540
  541 QVALGTAKLN YLDPRISIAW CKRFGVPVEK IYNKTQRERF AWAFNQAGED FEF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: TOP1M_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: