Protein Overview: DHB8_RAT

General Information:
Name(s) found:	DHB8_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81892005\|sp\|Q6MGB5.1\|DHB8_RAT RecName: Full=Estradiol 17-beta-dehydrogenase 8; AltName: Full=Testosterone 17-beta-dehydrogenase 8; AltName: Full=17-beta-hydroxysteroid dehydrogenase 8; Short=17-beta-HSD 8 [NCBI NR] gi\|47087119\|ref\|NP_997694.1\| estradiol 17 beta-dehydrogenase 8 [Rattus norvegicus] [NCBI NR] gi\|46237550\|emb\|CAE83931.1\| hydroxysteroid (17-beta) dehydrogenase 8 [Rattus norvegicus] [NCBI NR] gi\|149043378\|gb\|EDL96829.1\| hydroxysteroid (17-beta) dehydrogenase 8, isoform CRA_c [Rattus norvegicus] [NCBI NR] Estradiol 17-beta-dehydrogenase 8 OS=Rattus norvegicus GN=Hsd17b8 PE=1 SV=1 [Swiss-Prot] similar to KE6a [HMR_022704-rand.fasta] hydroxysteroid (17-beta) dehydrogenase 8 [071204_hmrz_cont.fasta] hydroxysteroid (17-beta) dehydrogenase 8 [Rattus norvegicus]gi\|47087119\|ref\|NP_997694.1\| hydroxysteroid (17-beta) dehydrogenase 8 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Hydroxysteroid (17-beta) dehydrogenase 8 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Estradiol 17-beta-dehydrogenase 8 (Testosterone 17-beta-dehydrogenase 8) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hydroxysteroid (17-beta) dehydrogenase 8 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hydroxysteroid (17-beta) dehydrogenase 8, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] estradiol 17 beta-dehydrogenase 8 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Hsd17b8 Estradiol 17-beta-dehydrogenase 8 [rat-ipi-250309-contam.fasta] Estradiol 17-beta-dehydrogenase 8 OS=Rattus norvegicus GN=Hsd17b8 [011711_HMR.fasta] Estradiol 17-beta-dehydrogenase 8 OS=Rattus norvegicus GN=Hsd17b8 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta] Estradiol 17-beta-dehydrogenase 8 OS=Rattus norvegicus GN=Hsd17b8 PE=3 SV=1 [20141208_RAT.fasta]
Organism:	Rattus norvegicus
Length:	259 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IEA] mitochondrial matrix [UNKNOWN][IEA] mitochondrion [UNKNOWN][IEA] mitochondrial envelope [UNKNOWN][IEA] plasma membrane [UNKNOWN][IEA]
Biological Process:	estrogen biosynthetic process [UNKNOWN][ISS] androgen metabolic process [UNKNOWN][IEA] estrogen metabolic process [UNKNOWN] oxidation reduction [IEA] fatty acid biosynthetic process [IEA]
Molecular Function:	estradiol 17-beta-dehydrogenase activity [UNKNOWN][ISS] protein binding [UNKNOWN] 3-hydroxyacyl-CoA dehydrogenase activity [UNKNOWN] oxidoreductase activity [IEA] binding [IEA] testosterone 17-beta-dehydrogenase activity [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASQLRLRSA LALVTGAGSG IGRAISVRLA AEGAAVAACD LDGAAAQDTV RLLGNPGSED  60
   61 REPRGKHAAF QADVSEGPAA KRLLEQVQAC FFRPPSVVVS CAGITRDEFL LHMSEEDWDR 120
  121 VIAVNLKGTF LVTQAAAQAL VSSGGRGSII NISSIVGKVG NIGQTNYASS KAGVIGLTQT 180
  181 AARELGRHGI RCNSVLPGFI ATPMTQKMPE KVKDKVTAMI PLGHMGDPED VADVVAFLAS 240
  241 EDSGYITGAS VEVSGGLFM

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: DHB8_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: