Protein Overview: PLPL2_RAT

General Information:
Name(s) found:	PLPL2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	ref\|XP_347184.1\| similar to RIKEN cDNA 0610039C21 [Rattus norvegicus] [NCBI NR] gi\|34861242\|ref\|XP_341961.1\| PREDICTED: similar to transport-secretion protein [Rattus norvegicus] [NCBI NR] gi\|189095277\|ref\|NP_001101979.2\| patatin-like phospholipase domain containing 2 [Rattus norvegicus] [NCBI NR] gi\|150403923\|sp\|P0C548.1\|PLPL2_RAT RecName: Full=Patatin-like phospholipase domain-containing protein 2; AltName: Full=Adipose triglyceride lipase [NCBI NR] gi\|149061639\|gb\|EDM12062.1\| patatin-like phospholipase domain containing 2 (predicted), isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|109463181\|ref\|XP_001062456.1\| PREDICTED: similar to transport-secretion protein isoform 2 [Rattus norvegicus] [NCBI NR] Patatin-like phospholipase domain-containing protein 2 OS=Rattus norvegicus GN=Pnpla2 PE=1 SV=1 [Swiss-Prot] similar to RIKEN cDNA 0610039C21 [HMR_022704-rand.fasta] similar to RIKEN cDNA 0610039C21 [Rattus norvegicus]gi\|34861242\|ref\|XP_341961.1\| similar to RIKEN cDNA 0610039C21 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 PREDICTED: similar to transport-secretion protein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Similar to RIKEN cDNA 0610039C21 [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Patatin-like phospholipase domain-containing protein 2 (Adipose triglyceride lipase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] patatin-like phospholipase domain containing 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] patatin-like phospholipase domain containing 2 (predicted), isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SIMILAR TO RIKEN CDNA 0610039C21 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] PREDICTED: similar to transport-secretion protein isoform 2 [Rattus norvegicus] [nr-271106-contam.fasta] PREDICTED: similar to transport-secretion protein [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Pnpla2 Patatin-like phospholipase domain-containing protein 2 [rat-ipi-250309-contam.fasta] Patatin-like phospholipase domain-containing protein 2 OS=Rattus norvegicus GN=Pnpla2 [011711_HMR.fasta] Patatin-like phospholipase domain-containing protein 2 OS=Rattus norvegicus GN=Pnpla2 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	478 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IEA] integral to membrane [IEA] cytosol [UNKNOWN][IEA] plasma membrane [IEA]
Biological Process:	negative regulation of sequestering of triglyceride [UNKNOWN][ISS] lipid metabolic process [IEA] metabolic process [IEA] lipid catabolic process [IEA] positive regulation of triglyceride catabolic process [UNKNOWN][ISS] triglyceride catabolic process [UNKNOWN]
Molecular Function:	triglyceride lipase activity [ISS] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFPRETKWNI SFAGCGFLGV YHIGVASCLR EHAPFLVANA THIYGASAGA LTATALVTGA  60
   61 CLGEAGANII EVSKEARKRF LGPLHPSFNL VKTIRGCLLK TLPADCHTRA SGRLGISLTR 120
  121 VSDGENVIIS HFSSKDELIQ ANVCSTFIPV YCGLIPPTLQ GVRYVDGGIS DNLPLYELKN 180
  181 TITVSPFSGE SDICPQDSST NIHELRITNT SIQFNLRNLY RLSKALFPPE PMVLREMCKQ 240
  241 GYRDGLRFLR RNGLLNQPNP LLALPPVVPQ EEDAEEAAVT EERTGGEDRI LEHLPARLNE 300
  301 ALLEACVEPK DLMTTLSNML PVRLATAMMV PYTLPLESAV SFTIRLLEWL PDVPEDIRWM 360
  361 KEQTGSICQY LVMRAKRKLG DHLPSRLSEQ VELRRAQSLP SVPLSCATYS EALPNWVRNN 420
  421 LSLGDALAKW EECQRQLLLG LFCTNVAFPP DALRMRAPAS PTATDPATPQ DPSGLPPC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PLPL2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: