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Protein Overview: tou-PB

General Information:
Name(s) found: tou-PB / FBpp0087196 [FlyBase]
Description(s) found:
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  • gi|45551085|ref|NP_725062.2| toutatis, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45445580|gb|AAM68713.3| toutatis, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|16648218|gb|AAL25374.1| GH22615p [Drosophila melanogaster] [NCBI NR]
  • The gene toutatis is referred to in FlyBase by the symbol Dmel\tou (CG10897, FBgn0033636). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7466385..7503336. It has the cytological map location 48A2-48A3. It is reported to have molecular function</span>: chromatin binding. There is experimental evidence that it is involved in the biological process</span>: nervous system development. 45 alleles are reported. The phenotypes of these alleles are annotated with: wing vein L5; dorsocentral bristle; wing. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • (AAM68713) CG10897-PB (Fragment) [DrosMelano7227.FASTAC.txt]
  • CG10897-PB, isoform B [Drosophila melanogaster]gi|16648218|gb|AAL25374.1| GH22615p [Drosophila melanogaster]gi|45551085|ref|NP_725062.2| CG10897-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(7467332..7467488,7467554..7467675,7467740..7468210); ID=FBpp0087196; name=tou-PB; parent=FBgn0033636,FBtr0088094; dbxref=FlyBase:FBpp0087196,FlyBase_Annotation_IDs:CG10897-PB,GB_protein:AAM68713.3,REFSEQ:NP_725062,GB_protei [fly-100309-contam.fasta]
  • GH22615p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG10897-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • toutatis CG10897-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • toutatis, isoform B [Drosophila melanogaster] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • type=protein; loc=2R:complement(7467332..7467488,7467554..7467675,7467740..7468210); ID=FBpp0087196; name=tou-PB; parent=FBgn0033636,FBtr0088094; dbxref=FlyBase:FBpp0087196,FlyBase_Annotation_IDs:CG10897-PB,GB_protein:AAM68713.3,REFSEQ:NP_725062,GB_protein:AAM68713; MD5=a464a77f79430753935b2ae4f057ac5f; length=249; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(7467332..7467488,7467554..7467675,7467740..7468210); ID=FBpp0087196; name=tou-PB; parent=FBgn0033636,FBtr0088094; dbxref=FlyBase:FBpp0087196,FlyBase_Annotation_IDs:CG10897-PB,GB_protein:AAM68713.3,REFSEQ:NP_725062,GB_protein:AAM68713; MD5=a464a77f79430753935b2ae4f057ac5f; length=249; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • GH22615p OS=Drosophila melanogaster GN=tou PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(7467332..7467488,7467554..7467675,7467740..7468210); ID=FBpp0087196; name=tou-PB; parent=FBgn0033636,FBtr0088094; dbxref=FlyBase:FBpp0087196,FlyBase_Annotation_IDs:CG10897-PB,GB_protein:AAM68713.3,REFSEQ:NP_725062,GB_protein:AAM68713,FlyMine:FBpp0087196,modMine:FBpp0087196; MD5=a464a77f79430753935b2ae4f057ac5f; length=249; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(11580235..11580705,11580049..11580170,11579827..11579983)); ID=FBpp0087196; name=tou-PB; parent=FBgn0033636,FBtr0088094; dbxref=FlyBase:FBpp0087196,FlyBase_Annotation_IDs:CG10897-PB,GB_protein:AAM68713.3,REFSEQ:NP_725062,GB_protein:AAM68713,FlyMine:FBpp0087196,modMine:FBpp0087196; MD5=a464a77f79430753935b2ae4f057ac5f; length=249; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(11580235..11580705,11580049..11580170,11579827..11579983)); ID=FBpp0087196; name=tou-PB; parent=FBgn0033636,FBtr0088094; dbxref=FlyBase:FBpp0087196,FlyBase_Annotation_IDs:CG10897-PB,GB_protein:AAM68713.3,REFSEQ:NP_725062,GB_protein:AAM68713,FlyMine:FBpp0087196,modMine:FBpp0087196; MD5=a464a77f79430753935b2ae4f057ac5f; length=249; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A8DYA3, GH22615p OS=Drosophila melanogaster GN=tou PE=2 SV=1 [DROME.fasta.20160308]
  • FBpp0087196 type=protein; loc=2R:complement(join(11580235..11580705,11580049..11580170,11579827..11579983)); ID=FBpp0087196; name=tou-PB; parent=FBgn0033636,FBtr0088094; dbxref=FlyBase:FBpp0087196,FlyBase_Annotation_IDs:CG10897-PB,GB_protein:AAM68713.3,REFSEQ:NP_725062,GB_protein:AAM68713,FlyMine:FBpp0087196,modMine:FBpp0087196; MD5=a464a77f79430753935b2ae4f057ac5f; length=249; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(11580235..11580705,11580049..11580170,11579827..11579983)); ID=FBpp0087196; name=tou-PB; parent=FBgn0033636,FBtr0088094; dbxref=FlyBase:FBpp0087196,FlyBase_Annotation_IDs:CG10897-PB,GB_protein:AAM68713.3,REFSEQ:NP_725062,GB_protein:AAM68713,UniProt/TrEMBL:Q95T46,FlyMine:FBpp0087196,modMine:FBpp0087196; MD5=a464a77f79430753935b2ae4f057ac5f; length=249; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 249 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: chromatin remodeling [NAS]
    nervous system development [IMP]
    Molecular Function: DNA binding [IEA]
    zinc ion binding [IEA]
    protein binding [IEA]
    chromatin binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGVYPVYTP VAAGNFSAGL INQAPVQPAM PFANVVAMSP RAVTPTRTRT PTPTPAPTPP  60
   61 PPPPTPLLMQ ASPTATALHV NACQSPPQQQ HAQLMTMPSP PAIGVGTATN QMSPPPINIH 120
  121 AIQEAKEKLK QEKKEKHATK KLMKELAVCK TLLGEMELHE DSWPFLLPVN TKQFPTYRKI 180
  181 IKTPMDLSTI KKKLQDLSYK TREDFCVDVR QIFDNCEMFN EDDSPVGKAG HGMRKFFESR 240
  241 WGELTDKHS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139] FFAS03 1.34 No description for 2j63A was found.
    2 View Details [140..249] PSI-BLAST 30.69897 No description for 2e7oA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

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