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Protein Overview: ERp60-PA

General Information:
Name(s) found: ERp60-PA / FBpp0087164 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene ERp60 is referred to in FlyBase by the symbol Dmel\ERp60 (CG8983, FBgn0033663). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7775073..7778520. It has the cytological map location 48C5. Based on sequence similarity, it is predicted to have molecular function</span>: protein disulfide isomerase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protein folding. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 489 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    endoplasmic reticulum [IEA]
    Biological Process: cell redox homeostasis [IEA]
    protein folding [ISS]
    Molecular Function: protein disulfide isomerase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMWRLAGVLL LGFIAISSGA EQDVLELGDD DFATTLKQHE TTLVMFYAPW CGHCKRLKPE  60
   61 YAKAAEIVKD DDPPIKLAKV DCTEAGKETC SKYSVSGYPT LKIFRQDEVS QDYNGPREAS 120
  121 GIAKYMRAQV GPASKTVRTV AELKKFLDTK DTTLFGYFSD SDSKLAKIFL KFADKNREKY 180
  181 RFGHSSEKEV LDKQGETDKI VLIRAPHLSN KFESSSIKFE GSSESDLSTF VKENFHGLVG 240
  241 HRTQDSVKDF QNPLITAYYS VDYQKNPKGT NYWRNRVLKV AKEFVGQINF AIASKDDFQH 300
  301 ELNEYGYDFV GDKPVVLARD EKNLKYALKD EFSVENLQDF VEKLLANELE PYIKSEPIPE 360
  361 SNDAPVKVAV AKNFDDLVIN NGKDTLIEFY APWCGHCKKL SPIYEELAEK LQDEDVAIVK 420
  421 MDATANDVPP EFNVRGFPTL FWLPKDAKNK PVSYNGGREV DDFLKYIAKE ATTELKGFDR 480
  481 SGKPKKTEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..489] PSI-BLAST 65.154902 Crystal Structure of Yeast Protein Disulfide Isomerase


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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