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Protein Overview: ppk25-PA

General Information:
Name(s) found: ppk25-PA / FBpp0085501 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene pickpocket 25 is referred to in FlyBase by the symbol Dmel\ppk25 (CG33349, FBgn0053349). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2837890..2839663. It has the cytological map location 42E1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: sodium channel activity. There is experimental evidence that it is involved in the biological process</span>: response to pheromone; male courtship behavior. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 451 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    Biological Process: sodium ion transport [IEA]
    male courtship behavior [IMP]
    response to pheromone [IDA]
    Molecular Function: sodium channel activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESKMSRPKQ PDWLAELCQE SSIHGMPYIA RRDLHWAERL FWTFIILGSA YYAISSCLNQ  60
   61 WYRFRDNPIV YEYEYLFGLR IFPFVGITLC PRYHDETEIP RLINQTWGVD PSEDKEKAVY 120
  121 YRKFLLAING LRYSTLETLE PFENDTTLDN VNYLNILLTL QKKVIAVKIP PELAPIITEV 180
  181 GLCQTSSQLN RYGNPYGKLE TQDMEPMKQC GYLSNCITSL KPINSIVAPI FMYLHDVEEM 240
  241 MLPDDMRTPS FDAKDIESKD LDIMLHTTSA ESEVRNLPVA YRKCRFSDEN NLQYYSPYHP 300
  301 SLCRLECRIK WALSLCNCKP YFYVAAPEVP ICTVSGMLCL ARSKWLERPC DCYPSCREET 360
  361 FTIFKVSDQT GGDDNYSGER FERTLIINLQ ISRMGINRRV VFSTDQLIMS FGGAIGLFLG 420
  421 ASFMTIYGVV YFFLTFIAYT CKNRFCKRFF F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..451] PSI-BLAST 83.522879 No description for 2qtsA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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