Protein Overview: mus312-PA

General Information:
Name(s) found:	mus312-PA / FBpp0076550 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|45550548\|ref\|NP_648104.2\| mutagen-sensitive 312, isoform A [Drosophila melanogaster] [NCBI NR] gi\|45446018\|gb\|AAF50581.2\| mutagen-sensitive 312, isoform A [Drosophila melanogaster] [NCBI NR] Structure-specific endonuclease subunit SLX4 OS=Drosophila melanogaster GN=mus312 PE=1 SV=2 [Swiss-Prot] The gene mutagen-sensitive 312 is referred to in FlyBase by the symbol Dmel\mus312 (CG8601, FBgn0002909). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:7322231..7326571. It has the cytological map location 65F4-65F5. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: meiotic chromosome segregation; reciprocal meiotic recombination; resolution of meiotic recombination intermediates. 6 alleles are reported. The phenotype of these alleles is annotated with: presumptive oocyte. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] (AAF50581) CG8601-PA [DrosMelano7227.FASTAC.txt] CG8601-PA, isoform A [Drosophila melanogaster]gi\|45550548\|ref\|NP_648104.2\| CG8601-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(7322691..7322737,7322816..7323339,7323399..7324331,7324392..7324436,7324505..7326393); ID=FBpp0076550; name=mus312-PA; parent=FBgn0002909,FBtr0076839; dbxref=GB_protein:AAF50581.1,GB_protein:AAF50581.2,FlyBase:FBpp0076550,FlyBase [fly-100309-contam.fasta] mutagen-sensitive 312 CG8601-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] CG8601-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(7322691..7322737,7322816..7323339,7323399..7324331,7324392..7324436,7324505..7326393); ID=FBpp0076550; name=mus312-PA; parent=FBgn0002909,FBtr0076839; dbxref=GB_protein:AAF50581.1,GB_protein:AAF50581.2,FlyBase:FBpp0076550,FlyBase_Annotation_IDs:CG8601-PA,REFSEQ:NP_648104,GB_protein:AAF50581; MD5=698b43ab582a53504e62e867ec56c26d; length=1145; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(7322691..7322737,7322816..7323339,7323399..7324331,7324392..7324436,7324505..7326393); ID=FBpp0076550; name=mus312-PA; parent=FBgn0002909,FBtr0076839; dbxref=GB_protein:AAF50581.1,GB_protein:AAF50581.2,FlyBase:FBpp0076550,FlyBase_Annotation_IDs:CG8601-PA,REFSEQ:NP_648104,GB_protein:AAF50581; MD5=698b43ab582a53504e62e867ec56c26d; length=1145; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:join(7322691..7322737,7322816..7323339,7323399..7324331,7324392..7324436,7324505..7326393); ID=FBpp0076550; name=mus312-PA; parent=FBgn0002909,FBtr0076839; dbxref=GB_protein:AAF50581.1,GB_protein:AAF50581.2,FlyBase:FBpp0076550,FlyBase_Annotation_IDs:CG8601-PA,REFSEQ:NP_648104,GB_protein:AAF50581,FlyMine:FBpp0076550,modMine:FBpp0076550; MD5=698b43ab582a53504e62e867ec56c26d; length=1145; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(7329591..7329637,7329716..7330239,7330299..7331231,7331292..7331336,7331405..7333293); ID=FBpp0076550; name=mus312-PA; parent=FBgn0002909,FBtr0076839; dbxref=GB_protein:AAF50581.1,GB_protein:AAF50581.2,FlyBase:FBpp0076550,FlyBase_Annotation_IDs:CG8601-PA,REFSEQ:NP_648104,GB_protein:AAF50581,FlyMine:FBpp0076550,modMine:FBpp0076550; MD5=698b43ab582a53504e62e867ec56c26d; length=1145; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(7329591..7329637,7329716..7330239,7330299..7331231,7331292..7331336,7331405..7333293); ID=FBpp0076550; name=mus312-PA; parent=FBgn0002909,FBtr0076839; dbxref=GB_protein:AAF50581.1,GB_protein:AAF50581.2,FlyBase:FBpp0076550,FlyBase_Annotation_IDs:CG8601-PA,REFSEQ:NP_648104,GB_protein:AAF50581,FlyMine:FBpp0076550,modMine:FBpp0076550; MD5=698b43ab582a53504e62e867ec56c26d; length=1145; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0076550 type=protein; loc=3L:join(7329591..7329637,7329716..7330239,7330299..7331231,7331292..7331336,7331405..7333293); ID=FBpp0076550; name=mus312-PA; parent=FBgn0002909,FBtr0076839; dbxref=GB_protein:AAF50581.1,GB_protein:AAF50581.2,FlyBase:FBpp0076550,FlyBase_Annotation_IDs:CG8601-PA,REFSEQ:NP_648104,GB_protein:AAF50581,FlyMine:FBpp0076550,modMine:FBpp0076550; MD5=698b43ab582a53504e62e867ec56c26d; length=1145; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(7329591..7329637,7329716..7330239,7330299..7331231,7331292..7331336,7331405..7333293); ID=FBpp0076550; name=mus312-PA; parent=FBgn0002909,FBtr0076839; dbxref=GB_protein:AAF50581.1,GB_protein:AAF50581.2,FlyBase:FBpp0076550,FlyBase_Annotation_IDs:CG8601-PA,REFSEQ:NP_648104,GB_protein:AAF50581,UniProt/Swiss-Prot:Q9VS48,FlyMine:FBpp0076550,modMine:FBpp0076550; MD5=698b43ab582a53504e62e867ec56c26d; length=1145; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1145 amino acids
Gene Ontology:
Cellular Component:	protein complex [IDA]
Biological Process:	reciprocal meiotic recombination [IMP] [NOT]nucleotide-excision repair, DNA damage recognition [IMP] meiotic chromosome segregation [IMP] resolution of meiotic recombination intermediates [IMP]
Molecular Function:	protein binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRKTRRANF KNLQPRLTRS TKAAADTLSL SNFFATPENA EEVPSCLADI PVQPDPPAPK  60
   61 IKPIRTSNVF EKPGPKPKKA PKLKASTVST SSGARRGRGK SKQQPSISNF LRNEQIFAEV 120
  121 TAQHCMADNF SADDIEMALA LSKSESEKHG RLRLHDDDDA VVDLLDDEEK STERIRHKLQ 180
  181 KYGFRTAAKE DYKSLAVLPV VASKGGRRGK WANRFTSLTL RNPDVQQKKL EEKVSALLGQ 240
  241 EMRGKEPNGE DCCLTPYTVI TAALKELRAE GESRILREPS EGPIDDLESY YVTDLFEVSR 300
  301 TPAHHLLKNW AAIQGRDFSP ERETQKCRQL RQQHELVYAE LERYYGDPQK LEEEVMQELD 360
  361 ELEKLVADNM IEDDSVVINI VEAESSSTGS SPSKEPPDKR PKMTMEDKEN LQPTTSKASL 420
  421 TVPAQSTRCT SPDLFADSED EPDIVTTAIS NEPEDVRNLS MKVYKNVSIS ERSSSVAEIE 480
  481 IVSSNDEPSQ ITTYEVFSSD EVKTVSNATQ EKISFDDDFI DLTQEFDMVE FNESKPRTPN 540
  541 LIASSETDSN VDNLNGDTIL DFSSQEVSCP ISKELYAKYA KVETFPVWNA AAEEEDKIEF 600
  601 SLSMERDLKS SEQSSHQLGI LTTPNDTEHS SSFSELNFSR NSLRRSVSLS TDLSFKSPLN 660
  661 WKMNSSAEKR VSPAASPYKQ SDASVDLTQN SDDENDAILL SDEEINYSIW KGNKTVKDLD 720
  721 IGDDSSDSCF ASPVTKKRAI PQFQTEEDLD AFLMDFSTDG NGSQGSHSPN KSALSKERAE 780
  781 FGILDAAPSQ PFSLSELQSH ADKEKSSDNE INWAEASFLD APAKPLSRRS SHKFNELLAK 840
  841 ISKPAHNSGD DFDEFDQMVF QSTKEAASSA GETSDMPQGL DLLLKGEIKT TAIPETRAPG 900
  901 NQTPIEPQQV DVDGNVYSVR VCHTPKPDFA TLPESEILQQ LYKYGIKPLK RKQAVKMLEF 960
  961 IYNQTHPIMK TAAVQDLPAR SEPIVRSKST PVIMERPHSQ VAKSTSKTLK AIGTKKDLTF1020
 1021 NDATGEELLR FSQSLAPSLC DDFETFVMQT NVTKKTPQPL VPLHIAWHNL ICANPQLHES1080
 1081 VLTYEPIDLQ AVYLHLKHMG HRYDPKDLKT FFDRRCIIFR YELGAPGKQA ERHVRRHTKK1140
 1141 PSKRK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.75

Protein Overview: mus312-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: