Protein Overview: dlp-PB

General Information:
Name(s) found:	dlp-PB / FBpp0089384 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|45553095\|ref\|NP_996075.1\| dally-like, isoform B [Drosophila melanogaster] [NCBI NR] gi\|45445890\|gb\|AAS65005.1\| dally-like, isoform B [Drosophila melanogaster] [NCBI NR] The gene dally-like is referred to in FlyBase by the symbol Dmel\dlp (CG32146, FBgn0041604). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14625720..14664716. It has the cytological map location 70E5-70E7. It is reported to have molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; detection of light stimulus involved in visual perception; axon guidance; compound eye development; imaginal disc-derived wing margin morphogenesis; wing disc dorsal/ventral pattern formation; positive regulation of smoothened signaling pathway; Wnt receptor signaling pathway; regulation of imaginal disc growth; segment polarity determination. 39 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; external compound sense organ; organ system; cuticle; multi-cell-component structure; dorsal thoracic disc; compound cell cluster organ. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] (AAS65005) CG32146-PB [DrosMelano7227.FASTAC.txt] CG32146-PB, isoform B [Drosophila melanogaster]gi\|45553095\|ref\|NP_996075.1\| CG32146-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(14626173..14626482,14657396..14657560,14657936..14658170,14658761..14658900,14659027..14659229,14660180..14660515,14660575..14660841,14662396..14662943,14663004..14663173,14663273..14663718); ID=FBpp0089384; name=dlp-PB; parent=F [fly-100309-contam.fasta] CG32146-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] dally-like CG32146-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(14626173..14626482,14657396..14657560,14657936..14658170,14658761..14658900,14659027..14659229,14660180..14660515,14660575..14660841,14662396..14662943,14663004..14663173,14663273..14663718); ID=FBpp0089384; name=dlp-PB; parent=FBgn0041604,FBtr0075680; dbxref=FlyBase:FBpp0089384,GB_protein:AAS65005.1,FlyBase_Annotation_IDs:CG32146-PB,REFSEQ:NP_996075,GB_protein:AAS65005; MD5=77a8ca8ceea2ce10d36d8e993c5cf5fd; length=939; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(14626173..14626482,14657396..14657560,14657936..14658170,14658761..14658900,14659027..14659229,14660180..14660515,14660575..14660841,14662396..14662943,14663004..14663173,14663273..14663718); ID=FBpp0089384; name=dlp-PB; parent=FBgn0041604,FBtr0075680; dbxref=FlyBase:FBpp0089384,GB_protein:AAS65005.1,FlyBase_Annotation_IDs:CG32146-PB,REFSEQ:NP_996075,GB_protein:AAS65005; MD5=77a8ca8ceea2ce10d36d8e993c5cf5fd; length=939; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Dally-like, isoform B OS=Drosophila melanogaster GN=dlp PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
Organism:	Drosophila melanogaster
Length:	939 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] extracellular region [ISS] proteinaceous extracellular matrix [IEA]
Biological Process:	regulation of imaginal disc growth [IMP] detection of light stimulus involved in visual perception [IMP] positive regulation of smoothened signaling pathway [IMP] Wnt receptor signaling pathway [IGI][IMP][TAS] smoothened signaling pathway [IMP][TAS] segment polarity determination [IMP] imaginal disc-derived wing margin morphogenesis [IMP] wing disc dorsal/ventral pattern formation [IEP][IGI] axon guidance [IMP] decapentaplegic receptor signaling pathway [NAS] compound eye development [IMP]
Molecular Function:	protein binding [NAS] heparan sulfate proteoglycan binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLHQQQQQQH LHCRRKATAT TTARLVIFSS PLLLLLLTTH LPPTLQADNG PAPQVAALAA  60
   61 PNPAGGVAGS SIIDQFSPNC SAVTHIFQAR GIDAIEIPQK PSNERVLRYC ESPSVGTCCT 120
  121 YNMETRMAMQ SRQQLEGHTK DQISRMSGIL GSKATKFKDI FTALLKESRT QFNSMFIRTY 180
  181 GVIYERNSYV FSDLFKELET YFANGRVDLL EVMDKFFNTL YQKMFTVLNT QYTFDENQNQ 240
  241 KPHFMPVPVA AARISAKMVR RRKKKAKIAP TWLIAPERSP LVSAQLQRFA FIVIVLVCRT 300
  301 CFGTLSFIAI GQQQRQQRCR VIAGTCQPPA PSTLPKNSAH LVIRIFVIAQ MLCGGGKECA 360
  361 DDDVGEVGSG GDGVEPCHLQ VQISAAISTP NENIFPNIPH SFSTDLILFS SYMRCVSEHM 420
  421 KELKPFGDVP DKLSVQIKRS FVATRTYGQA LTTASEVAKK VLNVRLNADC TGALTKMQHC 480
  481 GACKGYTEKP CTNYCVNVIK GCLHYQHEFD SEWENFAMAM DKVAERLLGS FNIVMVVEPL 540
  541 NIKISEAIMN FQDSGQDITN RVFQGCGRPK LKKMKRSISP KLQGVQILNA RSPVEADTLD 600
  601 IDETLDEAIV LRERRAAEPG SQETSAQQSQ EQGVGKSGNG GGGGGGNNRR QQQRRKQQQQ 660
  661 RRKQQNNRDD NDDDDNESGG GREPILDRIV RDIRQRVKDY KKFWSNLPHS VCSNEDIASS 720
  721 SDVDGMCWNG HTIDRYMHSI TTEHGSNPEF TGNPASTKQT AQMASQLSHL KNAIVHLRNA 780
  781 YNGQDVEWSE QEELPYAGSG AGSGSGSEDD EDDDEGSGLG PFEPSHKPDV ERPSVDADND 840
  841 DDEDAGGRGH MPTHTSRPTS GVDDKNPLIH TTHFDQDHND LDEDHRQLDE DEDTDAGHDG 900
  901 ANDNRSSDAP EKMTLRRALV VYLLPLYMAW FGGVCADLL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: dlp-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: