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Protein Overview: Dhc62B-PB

General Information:
Name(s) found: Dhc62B-PB / FBpp0089250 [FlyBase]
Description(s) found:
Found 11 descriptions.
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  • The gene Dynein heavy chain at 62B is referred to in FlyBase by the symbol Dmel\Dhc62B (CG15804, FBgn0013811). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:1759172..1771650. It has the cytological map location 62B1-62B3. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; motor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: microtubule-based movement. 7 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 3966 amino acids

    Gene Ontology:
    Cellular Component: axonemal dynein complex [ISS]
    microtubule associated complex [ISS]
    Biological Process: microtubule-based movement [IEA][ISS]
    Molecular Function: nucleotide binding [IEA]
    microtubule motor activity [IEA]
    motor activity [ISS]
    ATPase activity, coupled [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTKKLERMH RPASDITKYD NEPYMKNPLL KFRISEVHER RHYQFLKQKA ADVKVRVARQ  60
   61 QWQPEPDMRL LPQSHYEDNL RREVRKIVVP PMLRRTEAKI LSFASERLKN KYPELVQAYM 120
  121 HDVHEEFNRL MKVYSMKNIL RHPEFSDEDP AQFELPRPDI GFRRPGRTQN YSNFLENRRR 180
  181 IAQKLLILQL PLRAILNISV GELPKLACIF NYVLATGAMQ QQLGLGGREA LSYKFYHKYI 240
  241 QNQLDKVNTF LRWTWYPKIV QVLRKLMRKR VMPMSTWKRS WNAMEALMNR EMTNMKIRTF 300
  301 EEMYRMCSHP RTMPMMRMSL EWSEFSSDLD TRPNAWSILR TFAEIATEIS MVGYRMEPLQ 360
  361 PQVQTLTSMA AYAKVNDYLK IEMNDNFLKD VIDKVQNIIL RTYQEVIQYV EGFRDKYYAL 420
  421 YSWQERDALN QFLSEPHEFE EYFARIDMYY GFIQMLRSEP ATEYFVMAVI HNEPAIFGLR 480
  481 TLAENLIHEI TTIIIREHIK AEVDICDEFE KIKYRALEIP KSTEELLESA EYMIHVKKDK 540
  541 IAELTDRIQY CLQVGTNIVE LTEMSKYHFD LTIKTINWIK DINDICDYNA SQQEQFKFTF 600
  601 EEHLQEVIKK LNSDIDELLP KLTVIDDMSR PDKFRDSYII LQNFIDQLKT FDDYVAWINK 660
  661 EEKLFKVALT EYPKLDIIKT FVYPFAELMK CCIEWQRYLS VWNDGPFEYL EPQFVERTTD 720
  721 DYLKEFQKNQ KYYRVKIKQD LIDNPVCKFK GQTEDPDPAK HPVPLRLCTS MIQSIKDFTT 780
  781 GVFIVNTMCN PALRKRHWKE MSEIAGFDVT PDAGTTLRKI LNSGLDPILD QFEIISIGAN 840
  841 KELQLWNALQ AMIKEWETRV FPYGPYKETG VQILSSLDDI QALLDDHILK TLVMRGSAFM 900
  901 KPCEEEVRAW YEKIMRVNET LDQWGKVQAN YLYLLPIFSS KDIVAQMPEE GRLFVIVEQT 960
  961 YTRNMGLVLR QPLVMETAPV SGLLESLQKA NELLEDIATG VSNYLEKKRL YFPRFFFLAN1020
 1021 DEMLEILSET KDPLRVLPHL SKCFEGINSL EFDAAKNVLA MISSDKETIE FIEQVSTAAA1080
 1081 GGSVEKWLIG VEDEMLKAVR YQNELSFAHY PKVKRHEWVL EWPQMTVLAI SQVYWASRVH1140
 1141 GCLRRTFGGN MTIMMNFFQE LSKELNDIVT LVRSPKISNL NRITIKSLIV IDVHAKDVSE1200
 1201 DLIKNKVSSE FDFQWLAQMR YYWEDDKTWV RIINATVPFA NEYLGNSDRL VITPLTDRCY1260
 1261 RTLVGAYQLH LNGAPEGPAG TGKTETTKDL AKALAVQCKV FNCSDGLDYK AMGKFFKGLA1320
 1321 SCGAWACFDE FNRIELEVLS VVAQQILLII QAVRSNATKF MFEGTELTLN PACYVCITMN1380
 1381 PGYAGRSELP DNLKVLFRSV AMMVPDYAMI GEISLYSYGF VDARKLAVKI VTTYRLCSEQ1440
 1441 LSSQNHYDYG MRAVKTVLSA CGNIKKQYPD EVEDILLLRS LIDVNLPKFL SFDVPLFEGI1500
 1501 ISDIFPGIKL PHIDYSLVES EFKRVCLEEV LEPAPSFLLK VIQTYEMIIV RHGFMLVGEP1560
 1561 LAGKSKTLQV LAKVLSALKI KAPQKSNYFQ HVQMGIMNPK SITMNQLYGS FDPISYEWTD1620
 1621 GLVAKIFRDF AMTPTPDRKW VIFDGPVDAV WIENMNTVLD DNKKLCLTSG EVITMSNEMS1680
 1681 MVFEVMDLAQ ASPATVSRCG MIYMEPSTLG WRAFAKSWLK KADPRWADEE GVPYVMALMQ1740
 1741 WLLPPCQTFV RRFCSQFIKP GEFNCMLTTF DLFDMQIAEA IEENPEDYQK YLQTYFQAAI1800
 1801 LFALIWGVGG VLDTASREKF DVFLKKVWLW DTDPPPPEPL GKMEITPPTE GLLVDYVFLY1860
 1861 KQRGAWRYWP DLAKRMDVEE TKTGVIVPTV DTARYIHLLK MHVEHKKRML LVGPTGTGKT1920
 1921 VYVQNYLMNK LDKEVFETGF ITFTVMISAN QCQDLLISKL QKWKRGIYGP PKGMQSVLFV1980
 1981 DDMNMPVKEV YGAQPPLELL RQFFDYGHVY DLKDSSKVYI HNVLIMAACG LPGGSRQDVY2040
 2041 ARFLNHFNVY SINTFSDDSM FRIFLNVALN GFRRAGHGQD VFVVTNQIVS ATQSIYKSVQ2100
 2101 SEIRATPSKS HYIFNLRDIS RVVTGCTLVR KESVSDKKIF VRVWYHEAMR VFYDRLVDDV2160
 2161 DRKWMFDKLN ECLKANFKDK VETVFERYCV QGPDEAVFTM EAASNILFGV YFDEDSVPDE2220
 2221 RRYEEVPSVE VFLNLALTSL DDYNSTRRNK MDITLFTFAL QHLNRICRII SIQGASALII2280
 2281 GLGGSGRQSL TKLATNMVQT SFFQPEITKN YGANDWHDDI KAILKEAGGM NKHTTFLITE2340
 2341 NQIKMELFLQ DIDCLLNQGE VPNIFPIDEK QEVLEMVRLA AQGGNRNIDV SALQVFSFFV2400
 2401 DRCKQKLHMI LSFSPIGDAL RTRVRLYPSL VNCCTIDWYD SWPEEALQMI AKMSLVDVNV2460
 2461 PSEDIKLAIM DTCQYFHTTA ARSTRAFCQM TGRHIYQTNA SFIELIRSFQ TLIERKQSET2520
 2521 MLAKMRYIGG LDTLAQAAAA ISIMQRDLNA LQPKLVALAE SSRKMMLEIN KETLAASAAA2580
 2581 EQVKRDEEVA SVQAEAAQVL KQDCERDLAK AIPVLEDALA ALNTLKPADI TLVKSMKNPP2640
 2641 PVIKLVMAAV CVIKGIPPER IPDPASGKMV QDYWGPSKRL LGEMNFLPGL KEFDKDNIPT2700
 2701 EIVKRIHKEF IPNKDFDPKV VAKASSAAKG LCQWIIAMMM YDEVAKVVAP KKAKLAGAEK2760
 2761 EYADTMEFLA QKRALALALE EKVALLNIEL DKANAEMQKT EEHAESCRNK LLRAEALIGG2820
 2821 LGGEKSRWNK AAEDLQELYD HLPGDVLISC GIIAYLSAVN LQYRSECVKD WFKKVTDLKI2880
 2881 PCSSHYSITD VLGLEVTIQN WQLDGLPNDE FSSENAIISA NSSRYSLFID PQAQANNWLK2940
 2941 NMERKNRLNC VKFNQSNYMK VIAEALEYGT PVIIENVQEE LEVPLDPILM RQTFVQGGIK3000
 3001 HISLGESVVP VNPNFRLYMT CNLRNPHFLP ETFNKVTVIN FALTQNALMD QLLSIVVAKE3060
 3061 RPDLQELRIT LTTEAAANKG ALRDAENMIL KTLSAGGDIL ENEAAIQILA DSKGLSKDIV3120
 3121 EKQEAAKETV AKIEAFRLNY KPVAVHSSIL YYSITDLPNI DPMYQFSLNW YINLYMYSIE3180
 3181 TANKSKDLPR RIKFLVDGFT RNLYNNVCRS IFEKDKLLYS FILTARILLG TGQVEMRHFA3240
 3241 HLVTNAKEST NIPPNPDPTW ITETVWLNVL RLEELKELRG IVDHFKSHLH AWQAIYDHSS3300
 3301 PEKQPLPPPW QDKTTAFEKI IVLKALRPDS VFLAVRLFIA ESIGDQYVTP PEFDISKSYA3360
 3361 DSTALTPLVF ILSPGADPLG SLLAFAEKMG QEETFQSISL GQGQGPIATA LIKNAQEMGY3420
 3421 WVCLQNCHLA ASWMPYLEYL WENMDTFNTT PNFRIWLTAY PTPQFPVTIL QNGVKMTNEP3480
 3481 PTGLKENLMR SYNSEPINDY EFYTGCAKQD RAFTRLLYGI CFFHAVVQER RKYGPLGWNI3540
 3541 AYGFNESDLQ ISVLQLSMLL NQYDHVPYDA ISYLTSECNY GGRVTDNWDR RLIVTILADF3600
 3601 CNAQAVTDNR YRFASDDRYI LPRKTEHREI LRYLDENLPS LAPPEVYGLH ANSGITRDLQ3660
 3661 TTKTLLDSMI LLLGSEAAGS AGAGVSVEQV ILDTIKQIER EMPADMDIEA AAEKYPVDYN3720
 3721 ESMNTVVVQE MERFLKLQKE IRTTCRDLAM GIKGIIVMTP DLENVMTAMK FNRIPTKWMS3780
 3781 KSYPCLKPLG SYVQDLYKRL NWLHDWHHHG KPPTFWLSGF FFTQAFLTGA MQNFARKYKI3840
 3841 PIDTLTFDYD VLKVETKTSP PDDGVYCNGL YLEGARWEWR ENTLVEQFPK VLIYAMPVIF3900
 3901 FRPVGLVDVV EGSRYRCPLY KTAERKGTLS TTGHSTNYVV PLLLNTHVKA SHWVKRSVAL3960
 3961 ICQTSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle