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Protein Overview: Start1-PB

General Information:
Name(s) found: Start1-PB / FBpp0088806 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Start1 is referred to in FlyBase by the symbol Dmel\Start1 (CG3522, FBgn0035028). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20462100..20465202. It has the cytological map location 60D5. Based on sequence similarity, it is predicted to have molecular function</span>: cholesterol binding; cholesterol transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: steroid biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 545 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: steroid biosynthetic process [IEA]
    Molecular Function: cholesterol binding [ISS]
    cholesterol transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNMDPSDVR STAQLILANA RQGNSAYNMQ YDMSRAHSIN LITEDFLAGY MQDGRMSVVR  60
   61 RFFCLFVTFD LVFVSLLWLI CIVINGDNIF TAFHKQIVEY TIYKSLFDVV AVAICRFLVL 120
  121 IFFYAILYIN HWSIIALSTS GSCLFLISKV FVFDWLDSKQ QVFEVILIIT SFILAWGEAW 180
  181 FLDCRVIPQE RHAQHYFRTM TSNDRTPMEQ PAILIEQERP PQSVTDFYSL MDTARHSDEE 240
  241 DELDDEYTQM GLDCLRKAYE IIESSDWKVE KVNQKGDTIH STQRDKIGKI YKLTARIKYP 300
  301 AKALMEDLFY RIEDCPKWNP ALLESKIVRK INSYTDITYQ VSVGGGGGMV KSRDFVNLRS 360
  361 CRLFYNGQIC DDDETAQLSS DDGNSSLNRS CEGSVSTISD GDSNTPLLPS SVSSCKATFP 420
  421 TSSKGAAMPF DTLGNSLGAK SLGPIVNFDE EPPPLDQDEF EDAKDKVDGE ANNMTKPNVP 480
  481 SVGKTKDRVW VTSAVSVQYA AVPPSPKYTS RLTLQFSEGR TLSVGLRFVK SLENRIAALW 540
  541 SGCFA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..184] MSA 3.032956 View MSA. No confident structure predictions are available.
    2 View Details [185..455] PSI-BLAST 43.045757 No description for 2r55A was found.
    3 View Details [456..545] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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