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Protein Overview: l(1)G0045-PA

General Information:
Name(s) found: l(1)G0045-PA / FBpp0070748 [FlyBase]
Description(s) found:
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  • gi|45549313|ref|NP_572236.3| lethal (1) G0045 [Drosophila melanogaster] [NCBI NR]
  • gi|45446816|gb|AAF46049.3| lethal (1) G0045 [Drosophila melanogaster] [NCBI NR]
  • The gene lethal (1) G0045 is referred to in FlyBase by the symbol Dmel\l(1)G0045 (CG32763, FBgn0026702). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:5516383..5520085. It has the cytological map location 5A8. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: ribonuclease P activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: tRNA 5'-leader removal. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • (AAF46049) CG32763-PA [DrosMelano7227.FASTAC.txt]
  • (AE003434) BcDNA:LD21623 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG32763-PA [Drosophila melanogaster]gi|45549313|ref|NP_572236.3| CG32763-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(5516757..5518440,5518508..5519397); ID=FBpp0070748; name=l(1)G0045-PA; parent=FBgn0026702,FBtr0070782; dbxref=GB_protein:AAF46049.2,GB_protein:AAF46049.3,FlyBase:FBpp0070748,FlyBase_Annotation_IDs:CG32763-PA,REFSEQ:NP_572236,GB_pr [fly-100309-contam.fasta]
  • CG32763-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • lethal (1) G0045 CG32763-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(5516757..5518440,5518508..5519397); ID=FBpp0070748; name=l(1)G0045-PA; parent=FBgn0026702,FBtr0070782; dbxref=GB_protein:AAF46049.2,GB_protein:AAF46049.3,FlyBase:FBpp0070748,FlyBase_Annotation_IDs:CG32763-PA,REFSEQ:NP_572236,GB_protein:AAF46049; MD5=d695cb71d97f8cbabcc90bfdac90e28f; length=857; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(5516757..5518440,5518508..5519397); ID=FBpp0070748; name=l(1)G0045-PA; parent=FBgn0026702,FBtr0070782; dbxref=GB_protein:AAF46049.2,GB_protein:AAF46049.3,FlyBase:FBpp0070748,FlyBase_Annotation_IDs:CG32763-PA,REFSEQ:NP_572236,GB_protein:AAF46049; MD5=d695cb71d97f8cbabcc90bfdac90e28f; length=857; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Lethal (1) G0045 OS=Drosophila melanogaster GN=l(1)G0045 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:join(5516757..5518440,5518508..5519397); ID=FBpp0070748; name=l(1)G0045-PA; parent=FBgn0026702,FBtr0070782; dbxref=GB_protein:AAF46049.2,GB_protein:AAF46049.3,FlyBase:FBpp0070748,FlyBase_Annotation_IDs:CG32763-PA,REFSEQ:NP_572236,GB_protein:AAF46049,FlyMine:FBpp0070748,modMine:FBpp0070748; MD5=d695cb71d97f8cbabcc90bfdac90e28f; length=857; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • FI18256p1 OS=Drosophila melanogaster GN=l(1)G0045 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=X:join(5622724..5624407,5624475..5625364); ID=FBpp0070748; name=l(1)G0045-PA; parent=FBgn0026702,FBtr0070782; dbxref=GB_protein:AAF46049.2,GB_protein:AAF46049.3,FlyBase:FBpp0070748,FlyBase_Annotation_IDs:CG32763-PA,REFSEQ:NP_572236,GB_protein:AAF46049,FlyMine:FBpp0070748,modMine:FBpp0070748; MD5=d695cb71d97f8cbabcc90bfdac90e28f; length=857; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(5622724..5624407,5624475..5625364); ID=FBpp0070748; name=l(1)G0045-PA; parent=FBgn0026702,FBtr0070782; dbxref=GB_protein:AAF46049.2,GB_protein:AAF46049.3,FlyBase:FBpp0070748,FlyBase_Annotation_IDs:CG32763-PA,REFSEQ:NP_572236,GB_protein:AAF46049,FlyMine:FBpp0070748,modMine:FBpp0070748; MD5=d695cb71d97f8cbabcc90bfdac90e28f; length=857; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FI18256p1 OS=Drosophila melanogaster GN=l(1)G0045 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0070748 type=protein; loc=X:join(5622724..5624407,5624475..5625364); ID=FBpp0070748; name=l(1)G0045-PA; parent=FBgn0026702,FBtr0070782; dbxref=GB_protein:AAF46049.2,GB_protein:AAF46049.3,FlyBase:FBpp0070748,FlyBase_Annotation_IDs:CG32763-PA,REFSEQ:NP_572236,GB_protein:AAF46049,FlyMine:FBpp0070748,modMine:FBpp0070748; MD5=d695cb71d97f8cbabcc90bfdac90e28f; length=857; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(5622724..5624407,5624475..5625364); ID=FBpp0070748; name=l(1)G0045-PA; parent=FBgn0026702,FBtr0070782; dbxref=GB_protein:AAF46049.2,GB_protein:AAF46049.3,FlyBase:FBpp0070748,FlyBase_Annotation_IDs:CG32763-PA,REFSEQ:NP_572236,GB_protein:AAF46049,UniProt/TrEMBL:Q7KVW2,FlyMine:FBpp0070748,modMine:FBpp0070748; MD5=d695cb71d97f8cbabcc90bfdac90e28f; length=857; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 857 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: tRNA 5'-leader removal [IEA]
    Molecular Function: ribonuclease P activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTQKVEYDA ALGGRVTLPS HVTTYHYAAE ALQEIRNLVA DCQETTQRSS KLIFQTLPKH  60
   61 MRRRAMSHHP KRLPRKYRQA HKSQMGKSGN QPVNGKRPSR KYRRRPKNLM REYVRRQRRH 120
  121 VWLETHIWHA KRFHMVDRWG HRLPYASCDK TYRACYRASA EHCLLQDISF YGCVELRGPL 180
  181 DMLREGFARL TSPQCGLGIT ARTFLSGRRE GSVELFEDGR YPYGALQRAS FMWRPRREEE 240
  241 DEKQTNHTLW LWLHPSGAQA VLNQLISVFQ LKSTRQQKLP LNEAVTEEKM DVDKIEPVEL 300
  301 SKETSPGKKN SKKKPEQRPL RFWTKTKAFD PQPSYFNSDG TLHLVLLQRE FNRFRLTGPR 360
  361 AQKVLFASLR PHREEELQDK ANYCQAALQL SSPAELLSNL VMAHLVVDPR LQRPKKRTKA 420
  421 VGKMEQPPLS AGDLLMNQPK SLPESPLWSK KARERLAKGI MSAHKYDQLR EQHAVVPGAP 480
  481 CAFEQQMQAL PVILIQRPGS QDPRYKRLGY GCGWDVIAPA GYGMTLWLTL TMWGARPGGL 540
  541 RELDSVAREA GAEIHLPDTL AGVQRAAASA DELRARYFRM PPNKRTNYRK LAVVSPFTAP 600
  601 WRHLVRDWRA SFSSASEGSS FYVLRHRQQL EEIVESIRHR SPLPQTLPDD AIIQIQLQLL 660
  661 SRGHVKDNAL ICLPTAADHK KRWRQLKHND QAPVHVEPTQ PDLNEQLRKE LRQSHKLKLK 720
  721 RLRSRRVREK RRLQETATKR VHIRPANTAH LVRGQLQEMC RLWLPTDPAE LRDSVRRQCS 780
  781 RQVFGYVSTA GFSFTEALVC AVGYVTPAGL QQLIEELPAS KGNRKQPPLM CLVRDADSRD 840
  841 YRWASFQVNL NVASPTF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..187] Pfam 43.60206 No description for PF06978.2 was found. No confident structure predictions are available.
    2 View Details [188..370] deduced N/A No confident structure predictions are available.
    3 View Details [371..507] deduced N/A No confident structure predictions are available.
    4 View Details [508..624] Pfam 44.677781 No description for PF08170.3 was found. No confident structure predictions are available.
    5 View Details [625..691] deduced N/A No confident structure predictions are available.
    6 View Details [692..857] MSA 1.04298 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle