Protein Overview: PPL

General Information:
Name(s) found:	PPL [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|45439327\|ref\|NP_002696.3\| periplakin [Homo sapiens] [NCBI NR] gi\|229462948\|sp\|O60437.3\|PEPL_HUMAN RecName: Full=Periplakin; AltName: Full=195 kDa cornified envelope precursor protein; AltName: Full=190 kDa paraneoplastic pemphigus antigen [NCBI NR] periplakin [HGNC (HUGO)] Periplakin OS=Homo sapiens GN=PPL PE=1 SV=3 [Swiss-Prot] periplakin; 195 kDa cornified envelope precursor; 190 kDa paraneoplastic pemphigus antigen [HMR_022704.fasta] periplakin [Homo sapiens] [nrdb_11152004_Chlamydomonas] periplakin; 195 kDa cornified envelope precursor; 190 kDa paraneoplastic pemphigus antigen [Homo sapiens] [HumanGallus06162005.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] IPI:IPI00298057.2\|SWISS-PROT:O60437\|ENSEMBL:ENSP00000340510\|REFSEQ:NP_002696\|H-INV:HIT000061654\|VEGA:OTTHUMP00000081390;OTTHUMP00000159922 Tax_Id=9606 Gene_Symbol=PPL Periplakin [ipi.HUMAN.fasta.20090807] Tax_Id=9606 Gene_Symbol=PPL Periplakin [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta] O60437;O60314;O60454;Q14C98; RecName: Full=Periplakin; AltName: Full=195 kDa cornified envelope precursor protein; AltName: Full=190 kDa paraneoplastic pemphigus antigen; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Periplakin OS=Homo sapiens GN=PPL [011711_HMR.fasta] GeneSymbol=PPL Synonyms=KIAA0568\|MGC134872 periplakin [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] Periplakin OS=Homo sapiens GN=PPL PE=1 SV=4 VAR_055129 [swiss.HUMAN.20141123.contam.amyloid.poly.fasta]
Organism:	Homo sapiens
Length:	1756 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSLFRKRNK GKYSPTVQTR SISNKELSEL IEQLQKNADQ VEKNIVDTEA KMQSDLARLQ  60
   61 EGRQPEHRDV TLQKVLDSEK LLYVLEADAA IAKHMKHPQG DMIAEDIRQL KERVTNLRGK 120
  121 HKQIYRLAVK EVDPQVNWAA LVEEKLDKLN NQSFGTDLPL VDHQVEEHNI FHNEVKAIGP 180
  181 HLAKDGDKEQ NSELRAKYQK LLAASQARQQ HLSSLQDYMQ RCTNELYWLD QQAKGRMQYD 240
  241 WSDRNLDYPS RRRQYENFIN RNLEAKEERI NKLHSEGDQL LAAEHPGRNS IEAHMEAVHA 300
  301 DWKEYLNLLI CEESHLKYME DYHQFHEDVK DAQELLRKVD SDLNQKYGPD FKDRYQIELL 360
  361 LRELDDQEKV LDKYEDVVQG LQKRGQQVVP LKYRRETPLK PIPVEALCDF EGEQGLISRG 420
  421 YSYTLQKNNG ESWELMDSAG NKLIAPAVCF VIPPTDPEAL ALADSLGSQY RSVRQKAAGS 480
  481 KRTLQQRYEV LKTENPGDAS DLQGRQLLAG LDKVASDLDR QEKAITGILR PPLEQGRAVQ 540
  541 DSAERAKDLK NITNELLRIE PEKTRSTAEG EAFIQALPGS GTTPLLRTRV EDTNRKYEHL 600
  601 LQLLDLAQEK VDVANRLEKS LQQSWELLAT HENHLNQDDT VPESSRVLDS KGQELAAMAC 660
  661 ELQAQKSLLG EVEQNLQAAK QCSSTLASRF QEHCPDLERQ EAEVHKLGQR FNNLRQQVER 720
  721 RAQSLQSAKA AYEHFHRGHD HVLQFLVSIP SYEPQETDSL SQMETKLKNQ KNLLDEIASR 780
  781 EQEVQKICAN SQQYQQAVKD YELEAEKLRS LLDLENGRSS HVSKRARLQS PATKVKEEEA 840
  841 ALAAKFTEVY AINRQRLQNL EFALNLLRQQ PEVEVTHETL QRNRPDSGVE EAWKIRKELD 900
  901 EETERRRQLE NEVKSTQEEI WTLRNQGPQE SVVRKEVLKK VPDPVLEESF QQLQRTLAEE 960
  961 QHKNQLLQEE LEALQLQLRA LEQETRDGGQ EYVVKEVLRI EPDRAQADEV LQLREELEAL1020
 1021 RRQKGAREAE VLLLQQRVAA LAEEKSRAQE KVTEKEVVKL QNDPQLEAEY QQLQEDHQRQ1080
 1081 DQLREKQEEE LSFLQDKLKR LEKERAMAEG KITVKEVLKV EKDAATEREV SDLTRQYEDE1140
 1141 AAKARASQRE KTELLRKIWA LEEENAKVVV QEKVREIVRP DPKAESEVAN LRLELVEQER1200
 1201 KYRGAEEQLR SYQSELEALR RRGPQVEVKE VTKEVIKYKT DPEMEKELQR LREEIVDKTR1260
 1261 LIERCDLEIY QLKKEIQALK DTKPQVQTKE VVQEILQFQE DPQTKEEVAS LRAKLSEEQK1320
 1321 KQVDLERERA SQEEQIARKE EELSRVKERV VQQEVVRYEE EPGLRAEASA FAESIDVELR1380
 1381 QIDKLRAELR RLQRRRTELE RQLEELERER QARREAEREV QRLQQRLAAL EQEEAEAREK1440
 1441 VTHTQKVVLQ QDPQQAREHA LLRLQLEEEQ HRRQLLEGEL ETLRRKLAAL EKAEVKEKVV1500
 1501 LSESVQVEKG DTEQEIQRLK SSLEEESRSK RELDVEVSRL EARLSELEFH NSKSSKELDF1560
 1561 LREENHKLQL ERQNLQLETR RLQSEINMAA TETRDLRNMT VADSGTNHDS RLWSLERELD1620
 1621 DLKRLSKDKD LEIDELQKRL GSVAVKREQR ENHLRRSIVV IHPDTGRELS PEEAHRAGLI1680
 1681 DWNMFVKLRS QECDWEEISV KGPNGESSVI HDRKSGKKFS IEEALQSGRL TPAQYDRYVN1740
 1741 KDMSIQELAV LVSGQK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	gi\|14317902, gi\|...	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PPL

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: