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Protein Overview: gi|22035612

General Information:
Name(s) found: gi|22035612 [NCBI NR]
Description(s) found:
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  • gi|22035612|ref|NP_665682.1| oxysterol-binding protein-like protein 6 isoform b [Homo sapiens] [NCBI NR]
  • oxysterol-binding protein-like protein 6 isoform b; oxysterol-binding protein-related protein 6; OSBP-related protein 6 [HMR_022704.fasta]
  • oxysterol-binding protein-like protein 6 isoform b [Homo sapiens] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=9606 oxysterol-binding protein-like protein 6 isoform b [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_145739) oxysterol-binding protein-like protein 6 isoform b; oxysterol-binding protein-related protein 6; OSBP-related protein 6 [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • oxysterol-binding protein-like protein 6 isoform b; oxysterol-binding protein-related protein 6; OSBP-related protein 6 [Homo sapiens] [HumanGallus06162005.fasta]
  • Tax_Id=9606 Gene_Symbol=OSBPL6 Isoform 3 of Oxysterol-binding protein-related protein 6 [human-ipi-250309-contam.fasta]
  • IPI:IPI00167804.7|SWISS-PROT:Q9BZF3-3|ENSEMBL:ENSP00000318723|REFSEQ:NP_665682|VEGA:OTTHUMP00000205308 Tax_Id=9606 Gene_Symbol=OSBPL6 Isoform 3 of Oxysterol-binding protein-related protein 6 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=OSBPL6 oxysterol-binding protein-like protein 6 isoform b [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
  • Isoform 3 of Oxysterol-binding protein-related protein 6 OS=Homo sapiens GN=OSBPL6 [011711_HMR.fasta]
  • GeneSymbol=OSBPL6 Synonyms=DKFZp686M06110|FLJ36583|FLJ41254|MGC59642|ORP6 oxysterol-binding protein-related protein 6 isoform b [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • Isoform 3 of Oxysterol-binding protein-related protein 6 GN=OSBPL6 [Doctor+uniprot-HUMAN-120911.fasta]
  • Isoform of Q9BZF3, Isoform 3 of Oxysterol-binding protein-related protein 6 OS=Homo sapiens GN=OSBPL6 [2016-04-human-contam-aPKC-His-Par6.fasta]
    • Organism: Homo sapiens
    Length: 938 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHQLSLIRGN RGRSIHILER TASSSTEPSV SRQLLEPEPV PLSKEADSWE IIEGLKIGQT  60
   61 NVQKPDKHEG FMLKKRKWPL KGWHKRFFVL DNGMLKYSKA PLDIQKGKVH GSIDVGLSVM 120
  121 SIKKKARRID LDTEEHIYHL KVKSQDWFDA WVSKLRHHRL YRQNEIVRSP RDASFHIFPS 180
  181 TSTAESSPAA NVSVMDGKMQ PNSFPWQSPL PCSNSLPATC TTGQSKVAAW LQDSEEMDRC 240
  241 AEDLAHCQSN LVELSKLLQN LEILQRTQSA PNFTDMQANC VDISKKDKRV TRRWRTKSVS 300
  301 KDTKIQLQEG PPAKGQFSTT RRRQRLAAAV ATTVPFSATM SPVRLHSSNP NLCADIEFQT 360
  361 PPSHLTDPLE SSTDYTKLQE EFCLIAQKVH SLLKSAFNSI AIEKEKLKQM VSEQDHSKGH 420
  421 STQMARLRQS LSQALNQNAE LRSRLNRIHS ESIICDQVVS VNIIPSPDEA GEQIHVSLPL 480
  481 SQQVANESRL SMSESVSEFF DAQEVLLSAS SSENEASDDE SYISDVSDNI SEDNTSVADN 540
  541 ISRQILNGEL TGGAFRNGRR ACLPAPCPDT SNINLWNILR NNIGKDLSKV SMPVELNEPL 600
  601 NTLQHLCEEM EYSELLDKAS ETDDPYERMV LVAAFAVSGY CSTYFRAGSK PFNPVLGETY 660
  661 ECIREDKGFR FFSEQVSHHP PISACHCESK NFVFWQDIRW KNKFWGKSME ILPVGTLNVM 720
  721 LPKYGDYYVW NKVTTCIHNI LSGRRWIEHY GEVTIRNTKS SVCICKLTFV KVNYWNSNMN 780
  781 EVQGVVIDQE GKAVYRLFGK WHEGLYCGVA PSAKCIWRPG SMPTNYELYY GFTRFAIELN 840
  841 ELDPVLKDLL PPTDARFRPD QRFLEEGNLE AAASEKQRVE ELQRSRRRYM EENNLEHIPK 900
  901 FFKKVIDANQ REAWVSNDTY WELRKDPGFS KVDSPVLW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..169] PSI-BLAST 16.69897 No description for 2q13A was found.
    2 View Details [170..270] deduced N/A No confident structure predictions are available.
    3 View Details [271..415] deduced N/A No confident structure predictions are available.
    4 View Details [416..564] deduced N/A No confident structure predictions are available.
    5 View Details [565..938] PSI-BLAST 82.0 Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • sterol binding
    		•  3.12877992228795 bayes_pls_golite062009
  • oxysterol binding
    		•  2.56824234952236 bayes_pls_golite062009
  • steroid binding
    		•  2.54679035876403 bayes_pls_golite062009
  • binding
    		•  1.67154210149282 bayes_pls_golite062009
  • lipid binding
    		•  1.46539100663772 bayes_pls_golite062009
    		• 0.35288515581255 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0867097353003303 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle