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Protein Overview: RFX1

General Information:
Name(s) found: RFX1 [HGNC (HUGO)]
Description(s) found:
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  • gi|238859557|ref|NP_002909.4| regulatory factor X1 [Homo sapiens] [NCBI NR]
  • gi|119604793|gb|EAW84387.1| regulatory factor X, 1 (influences HLA class II expression) [Homo sapiens] [NCBI NR]
  • regulatory factor X, 1 (influences HLA class II expression) [HGNC (HUGO)]
  • MHC class II regulatory factor RFX1 OS=Homo sapiens GN=RFX1 PE=1 SV=2 [Swiss-Prot]
  • regulatory factor X1; trans-acting regulatory factor 1; enhancer factor C; MHC class II regulatory factor RFX [HMR_022704.fasta]
  • (NM_002918) regulatory factor X1; trans-acting regulatory factor 1; enhancer factor C; MHC class II regulatory factor RFX [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • regulatory factor X1; trans-acting regulatory factor 1; enhancer factor C; MHC class II regulatory factor RFX [Homo sapiens] [HumanGallus06162005.fasta]
  • regulatory factor X, 1 (influences HLA class II expression) [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • regulatory factor X1 [Homo sapiens] [NCBI-RefSeq_human_na_07-13-2009_con_reversed.fasta]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=RFX1 MHC class II regulatory factor RFX1 [EBI-IPI_Human_3.71_03-24-2010_reversed.fasta]
  • MHC class II regulatory factor RFX1 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P22670; RecName: Full=MHC class II regulatory factor RFX1; AltName: Full=Transcription factor RFX1; AltName: Full=Regulatory factor X 1; AltName: Full=Enhancer factor C; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • MHC class II regulatory factor RFX1 OS=Homo sapiens GN=RFX1 [011711_HMR.fasta]
  • IPI:IPI00305337.2|SWISS-PROT:P22670|ENSEMBL:ENSP00000254325|REFSEQ:NP_002909|H-INV:HIT000053376|VEGA:OTTHUMP00000077965 Tax_Id=9606 Gene_Symbol=RFX1 MHC class II regulatory factor RFX1 [ipi.HUMAN.fasta.20100406]
  • GeneSymbol=RFX1 Synonyms=EFC|RFX MHC class II regulatory factor RFX1 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00305337.2|SWISS-PROT:P22670|ENSEMBL:ENSP00000254325|REFSEQ:NP_002909|H-INV:HIT000053376 Tax_Id=9606 Gene_Symbol=RFX1 MHC class II regulatory factor RFX1 [ipi.HUMAN.20110912.fasta]
  • MHC class II regulatory factor RFX1 GN=RFX1 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 979 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATQAYTELQ AAPPPSQPPQ APPQAQPQPP PPPPPAAPQP PQPPTAAATP QPQYVTELQS  60
   61 PQPQAQPPGG QKQYVTELPA VPAPSQPTGA PTPSPAPQQY IVVTVSEGAM RASETVSEAS 120
  121 PGSTASQTGV PTQVVQQVQG TQQRLLVQTS VQAKPGHVSP LQLTNIQVPQ QALPTQRLVV 180
  181 QSAAPGSKGG QVSLTVHGTQ QVHSPPEQSP VQANSSSSKT AGAPTGTVPQ QLQVHGVQQS 240
  241 VPVTQERSVV QATPQAPKPG PVQPLTVQGL QPVHVAQEVQ QLQQVPVPHV YSSQVQYVEG 300
  301 GDASYTASAI RSSTYSYPET PLYTQTASTS YYEAAGTATQ VSTPATSQAV ASSGSMPMYV 360
  361 SGSQVVASST STGAGASNSS GGGGSGGGGG GGGGGGGGGS GSTGGGGSGA GTYVIQGGYM 420
  421 LGSASQSYSH TTRASPATVQ WLLDNYETAE GVSLPRSTLY CHYLLHCQEQ KLEPVNAASF 480
  481 GKLIRSVFMG LRTRRLGTRG NSKYHYYGLR IKASSPLLRL MEDQQHMAMR GQPFSQKQRL 540
  541 KPIQKMEGMT NGVAVGQQPS TGLSDISAQV QQYQQFLDAS RSLPDFTELD LQGKVLPEGV 600
  601 GPGDIKAFQV LYREHCEAIV DVMVNLQFTL VETLWKTFWR YNLSQPSEAP PLAVHDEAEK 660
  661 RLPKAILVLL SKFEPVLQWT KHCDNVLYQG LVEILIPDVL RPIPSALTQA IRNFAKSLES 720
  721 WLTHAMVNIP EEMLRVKVAA AGAFAQTLRR YTSLNHLAQA ARAVLQNTAQ INQMLSDLNR 780
  781 VDFANVQEQA SWVCRCEDRV VQRLEQDFKV TLQQQNSLEQ WAAWLDGVVS QVLKPYQGSA 840
  841 GFPKAAKLFL LKWSFYSSMV IRDLTLRSAA SFGSFHLIRL LYDEYMYYLI EHRVAQAKGE 900
  901 TPIAVMGEFA NLATSLNPLD PDKDEEEEEE EESEDELPQD ISLAAGGESP ALGPETLEPP 960
  961 AKLARTDARG LFVQALPSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] deduced N/A No confident structure predictions are available.
    2 View Details [219..419] Pfam 108.677781 No description for PF04589.3 was found. No confident structure predictions are available.
    3 View Details [420..563] PSI-BLAST 21.0 Class II MHC transcription factor RFX1
    4 View Details [564..671] deduced N/A No confident structure predictions are available.
    5 View Details [672..863] deduced N/A No confident structure predictions are available.
    6 View Details [864..979] MSA 2.033991 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle