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Protein Overview: Kdm4B-PA, Kdm4B-...

General Information:
Name(s) found: Kdm4B-PD / FBpp0291264 [FlyBase]
Kdm4B-PC / FBpp0291263 [FlyBase]
Kdm4B-PB / FBpp0291262 [FlyBase]
Kdm4B-PA / FBpp0086883 [FlyBase]
Description(s) found:
Found 35 descriptions.
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  • The gene Histone demethylase 4B is referred to in FlyBase by the symbol Dmel\Kdm4B (CG33182, FBgn0053182). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9073242..9085869. It has the cytological map location 49F7. There is experimental evidence that it has the molecular function</span>: histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K9 specific). There is experimental evidence that it is involved in the biological process</span>: histone H3-K36 demethylation; histone H3-K9 demethylation. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • The gene Histone demethylase 4B is referred to in FlyBase by the symbol Dmel\Kdm4B (CG33182, FBgn0053182). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9073242..9085869. It has the cytological map location 49F7. There is experimental evidence that it has the molecular function</span>: histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K9 specific). There is experimental evidence that it is involved in the biological process</span>: histone H3-K36 demethylation; histone H3-K9 demethylation. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • The gene Histone demethylase 4B is referred to in FlyBase by the symbol Dmel\Kdm4B (CG33182, FBgn0053182). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9073242..9085869. It has the cytological map location 49F7. There is experimental evidence that it has the molecular function</span>: histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K9 specific). There is experimental evidence that it is involved in the biological process</span>: histone H3-K36 demethylation; histone H3-K9 demethylation. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
  • The gene Histone demethylase 4B is referred to in FlyBase by the symbol Dmel\Kdm4B (CG33182, FBgn0053182). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9073242..9085869. It has the cytological map location 49F7. There is experimental evidence that it has the molecular function</span>: histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K9 specific). There is experimental evidence that it is involved in the biological process</span>: histone H3-K36 demethylation; histone H3-K9 demethylation. 8 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 590 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: histone H3-K36 demethylation [IMP]
    histone H3-K9 demethylation [IDA][IMP]
    histone demethylation [ISS]
    Molecular Function: histone demethylase activity (H3-K9 specific) [IDA][IMP]
    transcription repressor activity [ISS]
    histone demethylase activity (H3-K36 specific) [IDA][IMP][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMSEVPRIK VFRPTWEEFK DFPKYVAYME SQGAHKAGLA KVVPPPEWVP RRSGYADLDA  60
   61 LNVTIPAPIC QVVTGKQGYY QQINIQKKPL TVKQFSELAS TERYATPKHF DFEDLERKYW 120
  121 KNITYVAPIY GADVSGSITD TDQDSWNINR LGTILDYVNK DYNIQIDGVN TAYLYFGMWK 180
  181 TTFAWHTEDM DLYSINYLHF GAPKTWYVVP PECGRKLEKV ANQYFPASYK NCNAYLRHKM 240
  241 TLISPQILKQ HDVPVSKITQ EAGEIMITFP FGYHAGFNHG FNCAESTNFA MERWIEYGKR 300
  301 AVQCTCSNDM VKISMDTFVK RFQSDRYDLW MEGRDVGRHP EDPPNAVLSA APLPPHLDVL 360
  361 LCDKKMKKQC NPTKAKSFKE RNPDLDLDEI QQNPNVPDDV KAMLKESVLT LDTGDLATDE 420
  421 ADFPNEDAMS LQSPANLKTK QELLEYIDDG TEDDDEEEDF KRRKQKRRYD ADYDDDWLAS 480
  481 KRKTNSRNNR GRSPRTKDDR SISPASSTSS TSRGARRGKA SGTPRKTPAR RKKDSITTSP 540
  541 AVSSAATAVK TPTSAVVAGT TSIATTTTPP ADGGGGESSS LGSHCTTASP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle