Protein Overview: Ir21a-PB

General Information:
Name(s) found:	Ir21a-PB / FBpp0111921 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|161076594\|ref\|NP_001097043.1\| CG2657 [Drosophila melanogaster] [NCBI NR] gi\|157400026\|gb\|AAF51569.2\| CG2657 [Drosophila melanogaster] [NCBI NR] The gene Ionotropic receptor 21a is referred to in FlyBase by the symbol Dmel\Ir21a (CG2657, FBgn0031209). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:21919..25151. It has the cytological map location 21A5-21B1. Based on sequence similarity, it is predicted to have molecular function</span>: extracellular-glutamate-gated ion channel activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] type=protein; loc=2L:complement(21919..22687,22743..22935,22994..23873,23929..24210,24747..25151); ID=FBpp0111921; name=CG2657-PB; parent=FBgn0031209,FBtr0113008; dbxref=FlyBase:FBpp0111921,FlyBase_Annotation_IDs:CG2657-PB,REFSEQ:NP_001097043,GB_protein:A [fly-100309-contam.fasta] type=protein; loc=2L:complement(21919..22687,22743..22935,22994..23873,23929..24210,24747..25151); ID=FBpp0111921; name=CG2657-PB; parent=FBgn0031209,FBtr0113008; dbxref=FlyBase:FBpp0111921,FlyBase_Annotation_IDs:CG2657-PB,REFSEQ:NP_001097043,GB_protein:AAF51569; MD5=2fc5d1a13fe6233836c5e769b12d3a0d; length=842; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(21919..22687,22743..22935,22994..23873,23929..24210,24747..25151); ID=FBpp0111921; name=Ir21a-PB; parent=FBgn0031209,FBtr0113008; dbxref=FlyBase:FBpp0111921,FlyBase_Annotation_IDs:CG2657-PB,REFSEQ:NP_001097043,GB_protein:AAF51569; MD5=2fc5d1a13fe6233836c5e769b12d3a0d; length=842; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Ionotropic receptor 21a OS=Drosophila melanogaster GN=Ir21a PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:complement(21919..22687,22743..22935,22994..23873,23929..24210,24747..25151); ID=FBpp0111921; name=Ir21a-PB; parent=FBgn0031209,FBtr0113008; dbxref=FlyBase:FBpp0111921,FlyBase_Annotation_IDs:CG2657-PB,REFSEQ:NP_001097043,GB_protein:AAF51569,FlyMine:FBpp0111921,modMine:FBpp0111921; MD5=2fc5d1a13fe6233836c5e769b12d3a0d; length=842; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(join(24747..25151,23929..24210,22994..23873,22743..22935,21919..22687)); ID=FBpp0111921; name=Ir21a-PB; parent=FBgn0031209,FBtr0113008; dbxref=FlyBase:FBpp0111921,FlyBase_Annotation_IDs:CG2657-PB,REFSEQ:NP_001097043,GB_protein:AAF51569,FlyMine:FBpp0111921,modMine:FBpp0111921; MD5=2fc5d1a13fe6233836c5e769b12d3a0d; length=842; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(24747..25151,23929..24210,22994..23873,22743..22935,21919..22687)); ID=FBpp0111921; name=Ir21a-PB; parent=FBgn0031209,FBtr0113008; dbxref=FlyBase:FBpp0111921,FlyBase_Annotation_IDs:CG2657-PB,REFSEQ:NP_001097043,GB_protein:AAF51569,FlyMine:FBpp0111921,modMine:FBpp0111921; MD5=2fc5d1a13fe6233836c5e769b12d3a0d; length=842; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Ionotropic receptor 21a OS=Drosophila melanogaster GN=Ir21a PE=4 SV=2 [DROME.fasta.20160308] FBpp0111921 type=protein; loc=2L:complement(join(24747..25151,23929..24210,22994..23873,22743..22935,21919..22687)); ID=FBpp0111921; name=Ir21a-PB; parent=FBgn0031209,FBtr0113008; dbxref=FlyBase:FBpp0111921,FlyBase_Annotation_IDs:CG2657-PB,REFSEQ:NP_001097043,GB_protein:AAF51569,FlyMine:FBpp0111921,modMine:FBpp0111921; MD5=2fc5d1a13fe6233836c5e769b12d3a0d; length=842; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(24747..25151,23929..24210,22994..23873,22743..22935,21919..22687)); ID=FBpp0111921; name=Ir21a-PB; parent=FBgn0031209,FBtr0113008; dbxref=FlyBase:FBpp0111921,FlyBase_Annotation_IDs:CG2657-PB,REFSEQ:NP_001097043,GB_protein:AAF51569,UniProt/Swiss-Prot:Q9VPI2,FlyMine:FBpp0111921,modMine:FBpp0111921; MD5=2fc5d1a13fe6233836c5e769b12d3a0d; length=842; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	842 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA]
Biological Process:	NONE FOUND
Molecular Function:	extracellular-glutamate-gated ion channel activity [IEA][ISS] ionotropic glutamate receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYYWVALVL FTAQAFSIEG DRSASYQEKC ISRRLINHYQ LNKEIFGVGM CDGNNENEFR  60
   61 QKRRIVPTFQ GNPRPRGELL ASKFHVNSYN FEQTNSLVGL VNKIAQEYLN KCPPVIYYDS 120
  121 FVEKSDGLIL ENLFKTIPIT FYHGEINADY EAKNKRFTSH IDCNCKSYIL FLSDPLMTRK 180
  181 ILGPQTESRV VLVSRSTQWR LRDFLSSELS SNIVNLLVIG ESLMADPMRE RPYVLYTHKL 240
  241 YADGLGSNTP VVLTSWIKGA LSRPHINLFP SKFQFGFAGH RFQISAANQP PFIFRIRTLD 300
  301 SSGMGQLRWD GVEFRLLTMI SKRLNFSIDI TETPTRSNTR GVVDTIQEQI IERTVDIGMS 360
  361 GIYITQERLM DSAMSVGHSP DCAAFITLAS KALPKYRAIM GPFQWPVWVA LICVYLGGIF 420
  421 PIVFTDRLTL SHLMGNWGEV ENMFWYVFGM FTNAFSFTGK YSWSNTRKNS TRLLIGAYWL 480
  481 FTIIITSCYT GSIIAFVTLP AFPDTVDSVL DLLGLFFRVG TLNNGGWETW FQNSTHIPTS 540
  541 RLYKKMEFVG SVDEGIGNVT QSFFWNYAFL GSKAQLEYLV QSNFSDENIS RRSALHLSEE 600
  601 CFALFQIGFL FPRESVYKIK IDSMILLAQQ SGLIAKINNE VSWVMQRSSS GRLLQASSSN 660
  661 SLREIIQEER QLTTADTEGM FLLMALGYFL GATALVSEIV GGITNKCRQI IKRSRKSAAS 720
  721 SWSSASSGSM LRTNAEQLSH DKRKANRREA AEVAQKMSFG MRELNLTRAT LREIYGSYGA 780
  781 PETDHGQLDI VHTEFPNSSA KLNNIEDEES REALESLQRL DEFMDQMDND GNPSSHTFRI 840
  841 DN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Ir21a-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: