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Protein Overview: YCBY_ECOLI

General Information:
Name(s) found: YCBY_ECOLI [Swiss-Prot]
Description(s) found:
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  • pir||C64835 hypothetical protein b0948 - Escherichia coli (strain K-12) [NCBI NR]
  • dbj|BAA35706.1| Hypothetical protein HI0115 [Escherichia coli] [NCBI NR]
  • gi|2501582|sp|P75864.1|RLML_ECOLI RecName: Full=Ribosomal RNA large subunit methyltransferase L; AltName: Full=rRNA (guanine-N(2)-)-methyltransferase rlmL; AltName: Full=23S rRNA m2G2445 methyltransferase [NCBI NR]
  • UPF0020/UPF0064 protein ycbY - Escherichia coli [Swiss-Prot]
  • putative methyltransferase; putative oxidoreductase [Escherichia coli K12]gi|1787181|gb|AAC74034.1| putative oxidoreductase; putative methyltransferase [Escherichia coli K12]gi|4062515|dbj|BAA35703.1| Hypothetical protein HI0115 [Escherichia coli K12]g [nrdb_11152004_Chlamydomonas]
  • UPF0020/UPF0064 protein ycbY [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • Ribosomal RNA large subunit methyltransferase L OS=Escherichia coli (strain K12) GN=rlmL PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 702 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSLFASTAR GLEELLKTEL ENLGAVECQV VQGGVHFKGD TRLVYQSLMW SRLASRIMLP  60
   61 LGECKVYSDL DLYLGVQAIN WTEMFNPGAT FAVHFSGLND TIRNSQYGAM KVKDAIVDAF 120
  121 TRKNLPRPNV DRDAPDIRVN VWLHKETASI ALDLSGDGLH LRGYRDRAGI APIKETLAAA 180
  181 IVMRSGWQPG TPLLDPMCGS GTLLIEAAML ATDRAPGLHR GRWGFSGWAQ HDEAIWQEVK 240
  241 AEAQTRARKG LAEYSSHFYG SDSDARVIQR ARTNARLAGI GELITFEVKD VAQLTNPLPK 300
  301 GPYGTVLSNP PYGERLDSEP ALIALHSLLG RIMKNQFGGW NLSLFSASPD LLSCLQLRAD 360
  361 KQYKAKNGPL DCVQKNYHVA ESTPDSKPAM VAEDYTNRLR KNLKKFEKWA RQEGIECYRL 420
  421 YDADLPEYNV AVDRYADWVV VQEYAPPKTI DAHKARQRLF DIIAATISVL GIAPNKLVLK 480
  481 TRERQKGKNQ YQKLGEKGEF LEVTEYNAHL WVNLTDYLDT GLFLDHRIAR RMLGQMSKGK 540
  541 DFLNLFSYTG SATVHAGLGG ARSTTTVDMS RTYLEWAERN LRLNGLTGRA HRLIQADCLA 600
  601 WLREANEQFD LIFIDPPTFS NSKRMEDAFD VQRDHLALMK DLKRLLRAGG TIMFSNNKRG 660
  661 FRMDLDGLAK LGLKAQEITQ KTLSQDFARN RQIHNCWLIT AA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..359] FFAS03 2.65 No description for 2okcA was found.
    2 View Details [360..702] PSI-BLAST 44.69897 Crystal Structure of PH1915 (APC 5817): A Hypothetical RNA Methyltransferase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methyltransferase activity
    		•  3.68431317301075 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  3.65102636703195 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  3.60853685152199 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  2.91374296950366 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  2.63941856307703 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  2.62081022854657 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  2.60624413031692 bayes_pls_golite062009
  • transferase activity
    		•  1.97261773840408 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.5770892133978 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  1.41988260132739 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  1.34038096673696 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  1.22300870226526 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  1.17774160785818 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  1.17774160785818 bayes_pls_golite062009
  • catalytic activity
    		•  1.16970557486814 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  0.752031224323003 bayes_pls_golite062009
  • rRNA (guanine) methyltransferase activity
    		•  0.724178554958878 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  0.663671542316122 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.286806504860858 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  0.24819970199694 bayes_pls_golite062009
  • rRNA (guanine-N2-)-methyltransferase activity
    		•  0.0808109576693168 bayes_pls_golite062009
    2
    Term Confidence Notes
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  4.09362182773099 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.39429041855776 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.07428840534971 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  3.0539218951403 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  3.01384869242051 bayes_pls_golite062009
  • transferase activity
    		•  2.22303238506686 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  1.90505369820945 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  1.83964463328968 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  1.75675289134467 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  1.63765148226572 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  1.6030970825293 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  1.6030970825293 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  1.12859857407629 bayes_pls_golite062009
  • rRNA (guanine) methyltransferase activity
    		•  1.10713374933008 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  1.05897361334523 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  0.639377525568296 bayes_pls_golite062009
  • rRNA (guanine-N2-)-methyltransferase activity
    		•  0.427131446117391 bayes_pls_golite062009
  • rRNA (cytosine) methyltransferase activity
    		•  0.346042596102079 bayes_pls_golite062009
  • O-methyltransferase activity
    		•  0.250946859465502 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  0.130104080746388 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  0.130042730841119 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle