Protein Overview: SC6A4_RAT

General Information:
Name(s) found:	SC6A4_RAT [Swiss-Prot]
Description(s) found: Found 21 descriptions. SHOW ALL	Sodium-dependent serotonin transporter OS=Rattus norvegicus GN=Slc6a4 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	630 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] integral to plasma membrane [IEA] membrane raft [IMP] cytosol [UNKNOWN][IEA] plasma membrane [UNKNOWN][IEA]
Biological Process:	neurotransmitter transport [IEA] serotonin uptake [UNKNOWN][IMP] locomotory behavior [NAS] neurotransmitter uptake [UNKNOWN] serotonin transport [UNKNOWN][IMP][TAS] response to toxin [UNKNOWN][IEA] monoamine transport [UNKNOWN] thalamus development [UNKNOWN][IEA]
Molecular Function:	protein binding [UNKNOWN] serotonin transmembrane transporter activity [UNKNOWN][IMP][TAS] protein homodimerization activity [IMP] protein C-terminus binding [UNKNOWN][IEA] symporter activity [IEA] monoamine transmembrane transporter activity [UNKNOWN] serotonin:sodium symporter activity [UNKNOWN][IEA] cocaine binding [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METTPLNSQK VLSECKDRED CQENGVLQKG VPTTADRAEP SQISNGYSAV PSTSAGDEAS  60
   61 HSIPAATTTL VAEIRQGERE TWGKKMDFLL SVIGYAVDLG NIWRFPYICY QNGGGAFLLP 120
  121 YTIMAIFGGI PLFYMELALG QYHRNGCISI WRKICPIFKG IGYAICIIAF YIASYYNTII 180
  181 AWALYYLISS LTDRLPWTSC TNSWNTGNCT NYFAQDNITW TLHSTSPAEE FYLRHVLQIH 240
  241 QSKGLQDLGT ISWQLTLCIV LIFTVIYFSI WKGVKTSGKV VWVTATFPYI VLSVLLVRGA 300
  301 TLPGAWRGVV FYLKPNWQKL LETGVWVDAA AQIFFSLGPG FGVLLAFASY NKFNNNCYQD 360
  361 ALVTSVVNCM TSFVSGFVIF TVLGYMAEMR NEDVSEVAKD AGPSLLFITY AEAIANMPAS 420
  421 TFFAIIFFLM LITLGLDSTF AGLEGVITAV LDEFPHIWAK RREWFVLIVV ITCVLGSLLT 480
  481 LTSGGAYVVT LLEEYATGPA VLTVALIEAV AVSWFYGITQ FCSDVKEMLG FSPGWFWRIC 540
  541 WVAISPLFLL FIICSFLMSP PQLRLFQYNY PHWSIVLGYC IGMSSVICIP TYIIYRLIST 600
  601 PGTLKERIIK SITPETPTEI PCGDIRMNAV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SC6A4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: