Protein Overview: CAD

General Information:
Name(s) found:	CAD [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|50403731\|sp\|P27708.3\|PYR1_HUMAN RecName: Full=CAD protein; Includes: RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase; Includes: RecName: Full=Aspartate carbamoyltransferase; Includes: RecName: Full=Dihydroorotase [NCBI NR] gi\|41351087\|gb\|AAH65510.1\| Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [Homo sapiens] [NCBI NR] gi\|18105007\|ref\|NP_004332.2\| carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase [Homo sapiens] [NCBI NR] gi\|119621019\|gb\|EAX00614.1\| carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119621018\|gb\|EAX00613.1\| carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119621017\|gb\|EAX00612.1\| carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a [Homo sapiens] [NCBI NR] carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [HGNC (HUGO)] CAD protein OS=Homo sapiens GN=CAD PE=1 SV=3 [Swiss-Prot] carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase; CAD trifunctional protein; multifunctional protein CAD [HMR_022704.fasta] carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase [Homo sapiens]gi\|41351087\|gb\|AAH65510.1\| Carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase [Homo sapiens]gi\|50403731\|sp\|P27708\|PYR1_HUMAN CAD protein [Incl [nrdb_11152004_Chlamydomonas] CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase ; Aspartate carbamoyltransferase ; Dihydroorotase ] [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 CAD protein [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_004341) carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase; CAD trifunctional protein; multifunctional protein CAD [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase; CAD trifunctional protein; multifunctional protein CAD [Homo sapiens] [HumanGallus06162005.fasta] carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 CAD PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=CAD CAD protein [human-ipi-250309-contam.fasta] IPI:IPI00301263.2\|SWISS-PROT:P27708\|TREMBL:Q53SY7\|ENSEMBL:ENSP00000264705\|REFSEQ:NP_004332\|H-INV:HIT000261917\|VEGA:OTTHUMP00000122585 Tax_Id=9606 Gene_Symbol=CAD CAD protein [ipi.HUMAN.fasta.20090807] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=CAD CAD protein ENSG00000084774 IPI00301263 [drosphohumanreversed.fasta] CAD protein [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] P27708;Q6P0Q0; RecName: Full=CAD protein; Includes: RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase; Includes: RecName: Full=Aspartate carbamoyltransferase; Includes: RecName: Full=Dihydroorotase; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] CAD protein OS=Homo sapiens GN=CAD [011711_HMR.fasta] GeneSymbol=CAD Synonyms=- CAD protein [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] CAD protein GN=CAD [Doctor+uniprot-HUMAN-120911.fasta]
Organism:	Homo sapiens
Length:	2225 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAALVLEDGS VLRGQPFGAA VSTAGEVVFQ TGMVGYPEAL TDPSYKAQIL VLTYPLIGNY  60
   61 GIPPDEMDEF GLCKWFESSG IHVAALVVGE CCPTPSHWSA TRTLHEWLQQ HGIPGLQGVD 120
  121 TRELTKKLRE QGSLLGKLVQ NGTEPSSLPF LDPNARPLVP EVSIKTPRVF NTGGAPRILA 180
  181 LDCGLKYNQI RCLCQRGAEV TVVPWDHALD SQEYEGLFLS NGPGDPASYP SVVSTLSRVL 240
  241 SEPNPRPVFG ICLGHQLLAL AIGAKTYKMR YGNRGHNQPC LLVGSGRCFL TSQNHGFAVE 300
  301 TDSLPADWAP LFTNANDGSN EGIVHNSLPF FSVQFHPEHQ AGPSDMELLF DIFLETVKEA 360
  361 TAGNPGGQTV RERLTERLCP PGIPTPGSGL PPPRKVLILG SGGLSIGQAG EFDYSGSQAI 420
  421 KALKEENIQT LLINPNIATV QTSQGLADKV YFLPITPHYV TQVIRNERPD GVLLTFGGQT 480
  481 ALNCGVELTK AGVLARYGVR VLGTPVETIE LTEDRRAFAA RMAEIGEHVA PSEAANSLEQ 540
  541 AQAAAERLGY PVLVRAAFAL GGLGSGFASN REELSALVAP AFAHTSQVLV DKSLKGWKEI 600
  601 EYEVVRDAYG NCVTVCNMEN LDPLGIHTGE SIVVAPSQTL NDREYQLLRQ TAIKVTQHLG 660
  661 IVGECNVQYA LNPESEQYYI IEVNARLSRS SALASKATGY PLAYVAAKLA LGIPLPELRN 720
  721 SVTGGTAAFE PSVDYCVVKI PRWDLSKFLR VSTKIGSCMK SVGEVMGIGR SFEEAFQKAL 780
  781 RMVDENCVGF DHTVKPVSDM ELETPTDKRI FVVAAALWAG YSVDRLYELT RIDRWFLHRM 840
  841 KRIIAHAQLL EQHRGQPLPP DLLQQAKCLG FSDKQIALAV LSTELAVRKL RQELGICPAV 900
  901 KQIDTVAAEW PAQTNYLYLT YWGTTHDLTF RTPHVLVLGS GVYRIGSSVE FDWCAVGCIQ 960
  961 QLRKMGYKTI MVNYNPETVS TDYDMCDRLY FDEISFEVVM DIYELENPEG VILSMGGQLP1020
 1021 NNMAMALHRQ QCRVLGTSPE AIDSAENRFK FSRLLDTIGI SQPQWRELSD LESARQFCQT1080
 1081 VGYPCVVRPS YVLSGAAMNV AYTDGDLERF LSSAAAVSKE HPVVISKFIQ EAKEIDVDAV1140
 1141 ASDGVVAAIA ISEHVENAGV HSGDATLVTP PQDITAKTLE RIKAIVHAVG QELQVTGPFN1200
 1201 LQLIAKDDQL KVIECNVRVS RSFPFVSKTL GVDLVALATR VIMGEEVEPV GLMTGSGVVG1260
 1261 VKVPQFSFSR LAGADVVLGV EMTSTGEVAG FGESRCEAYL KAMLSTGFKI PKKNILLTIG1320
 1321 SYKNKSELLP TVRLLESLGY SLYASLGTAD FYTEHGVKVT AVDWHFEEAV DGECPPQRSI1380
 1381 LEQLAEKNFE LVINLSMRGA GGRRLSSFVT KGYRTRRLAA DFSVPLIIDI KCTKLFVEAL1440
 1441 GQIGPAPPLK VHVDCMTSQK LVRLPGLIDV HVHLREPGGT HKEDFASGTA AALAGGITMV1500
 1501 CAMPNTRPPI IDAPALALAQ KLAEAGARCD FALFLGASSE NAGTLGTVAG SAAGLKLYLN1560
 1561 ETFSELRLDS VVQWMEHFET WPSHLPIVAH AEQQTVAAVL MVAQLTQRSV HICHVARKEE1620
 1621 ILLIKAAKAR GLPVTCEVAP HHLFLSHDDL ERLGPGKGEV RPELGSRQDV EALWENMAVI1680
 1681 DCFASDHAPH TLEEKCGSRP PPGFPGLETM LPLLLTAVSE GRLSLDDLLQ RLHHNPRRIF1740
 1741 HLPPQEDTYV EVDLEHEWTI PSHMPFSKAH WTPFEGQKVK GTVRRVVLRG EVAYIDGQVL1800
 1801 VPPGYGQDVR KWPQGAVPQL PPSAPATSEM TTTPERPRRG IPGLPDGRFH LPPRIHRASD1860
 1861 PGLPAEEPKE KSSRKVAEPE LMGTPDGTCY PPPPVPRQAS PQNLGTPGLL HPQTSPLLHS1920
 1921 LVGQHILSVQ QFTKDQMSHL FNVAHTLRMM VQKERSLDIL KGKVMASMFY EVSTRTSSSF1980
 1981 AAAMARLGGA VLSFSEATSS VQKGESLADS VQTMSCYADV VVLRHPQPGA VELAAKHCRR2040
 2041 PVINAGDGVG EHPTQALLDI FTIREELGTV NGMTITMVGD LKHGRTVHSL ACLLTQYRVS2100
 2101 LRYVAPPSLR MPPTVRAFVA SRGTKQEEFE SIEEALPDTD VLYMTRIQKE RFGSTQEYEA2160
 2161 CFGQFILTPH IMTRAKKKMV VMHPMPRVNE ISVEVDSDPR AAYFRQAENG MYIRMALLAT2220
 2221 VLGRF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	None Entered	Sample pIC145 from april 2005	Okada, M., et al. (2006)
View Run	gi\|14317902, gi\|...	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Protein Overview: CAD

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: