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Protein Overview: PTHP_ECOLI

General Information:
Name(s) found: PTHP_ECOLI [Swiss-Prot]
Description(s) found:
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  • gi|76365074|sp|P0AA04.1|PTHP_ECOLI RecName: Full=Phosphocarrier protein HPr; AltName: Full=Histidine-containing protein [NCBI NR]
  • pir||WQECPH phosphotransferase system phosphohistidine-containing protein [validated] - Escherichia coli (strain K-12) [NCBI NR]
  • gi|66360306|pdb|1VRC|D Chain D, Complex Of Enzyme Iiamannose And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [NCBI NR]
  • gi|66360305|pdb|1VRC|C Chain C, Complex Of Enzyme Iiamannose And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [NCBI NR]
  • gi|576146|pdb|1HDN| Chain , Histidine-Containing Phosphocarrier Protein (Hpr) (Nmr, 30 Structures) [NCBI NR]
  • gi|5107743|pdb|3EZA|B Chain B, Complex Of The Amino Terminal Domain Of Enzyme I And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [NCBI NR]
  • gi|494453|pdb|1POH| Chain , Phosphotransferase (Histidine-Containing Phosphocarrier Protein) (Hpr) [NCBI NR]
  • gi|4139614|pdb|3EZB|B Chain B, Complex Of The Amino Terminal Domain Of Enzyme I And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli [NCBI NR]
  • gi|4139586|pdb|3EZE|B Chain B, Complex Of The Amino Terminal Domain Of Enzyme I And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [NCBI NR]
  • gi|3212690|pdb|2JEL|P Chain P, Jel42 FabHPR COMPLEX [NCBI NR]
  • gi|27065142|pdb|1J6T|B Chain B, Complex Of Enzyme Iiamtl And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [NCBI NR]
  • pir||G91039 PTS system protein HPr [imported] - Escherichia coli (strain O157:H7, substrain RIMD 0509952) [NCBI NR]
  • pir||B85884 PTS system protein HPr [imported] - Escherichia coli (strain O157:H7, substrain EDL933) [NCBI NR]
  • gi|224521|prf||1107231B protein,His containing [NCBI NR]
  • gi|209764216|gb|ACI80420.1| PTS system protein HPr [Escherichia coli] [NCBI NR]
  • gi|209764214|gb|ACI80419.1| PTS system protein HPr [Escherichia coli] [NCBI NR]
  • gi|209764212|gb|ACI80418.1| PTS system protein HPr [Escherichia coli] [NCBI NR]
  • gi|209764210|gb|ACI80417.1| PTS system protein HPr [Escherichia coli] [NCBI NR]
  • gi|209764208|gb|ACI80416.1| PTS system protein HPr [Escherichia coli] [NCBI NR]
  • gi|1799834|dbj|BAA16289.1| phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr) [Escherichia coli W3110] [NCBI NR]
  • gi|157833546|pdb|1POH|A Chain A, The 2.0 Angstroms Resolution Structure Of Escherichia Coli Histidine-Containing Phosphocarrier Protein Hpr: A Redetermination [NCBI NR]
  • gi|157833468|pdb|1PFH|A Chain A, The Phosphorylated Form Of The Histidine-Containing Phosphocarrier Protein Hpr [NCBI NR]
  • gi|157831305|pdb|1HDN|A Chain A, The High-Resolution Structure Of The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Determined By Restrained Molecular Dynamics From Nmr Nuclear Overhauser Effect Data [NCBI NR]
  • gi|147398|gb|AAA24440.1| HPr [NCBI NR]
  • gi|147395|gb|AAA24438.1| histidine-containing protein [NCBI NR]
  • gi|147263|gb|AAA24384.1| HPr protein (EC 2.7.1.68) [NCBI NR]
  • gi|145687|gb|AAA23655.1| ptsH protein [NCBI NR]
  • gi|1311140|pdb|1PFH| Chain , The Phosphorylated Form Of The Histidine-Containing Phosphocarrier Protein Hpr [NCBI NR]
  • gi|11513746|pdb|1GGR|B Chain B, Complex Of Enzyme Iiaglc And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [NCBI NR]
  • Phosphocarrier protein HPr (Histidine-containing protein) - Escherichia coli [Swiss-Prot]
  • PTS family Hpr protein, phosphohistidinoprotein-hexose phosphotransferase; PTS system protein HPr [Escherichia coli K12]gi|15832541|ref|NP_311314.1| Hpr; PTS system protein [Escherichia coli O157:H7]gi|30063809|ref|NP_837980.1| PTS system protein HPr [S [nrdb_11152004_Chlamydomonas]
  • Phosphocarrier protein HPr (Histidine-containing protein) [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • ptsH protein [nr-271106-contam.fasta]
  • HPr [nr-271106-contam.fasta]
  • HPr protein (EC 2.7.1.68) [nr-271106-contam.fasta]
  • Chain , The Phosphorylated Form Of The Histidine-Containing Phosphocarrier Protein Hpr [nr-271106-contam.fasta]
  • Chain D, Complex Of Enzyme Iiamannose And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [nr-271106-contam.fasta]
  • Chain B, Complex Of The Amino Terminal Domain Of Enzyme I And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [nr-271106-contam.fasta]
  • Chain B, Complex Of The Amino Terminal Domain Of Enzyme I And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli [nr-271106-contam.fasta]
  • Chain P, Jel42 FabHPR COMPLEX [nr-271106-contam.fasta]
  • Chain , Histidine-Containing Phosphocarrier Protein (Hpr) (Nmr, 30 Structures) [nr-271106-contam.fasta]
  • histidine-containing protein [nr-271106-contam.fasta]
  • Chain B, Complex Of Enzyme Iiaglc And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [nr-271106-contam.fasta]
  • Chain B, Complex Of Enzyme Iiamtl And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [nr-271106-contam.fasta]
  • protein,His containing [nr-271106-contam.fasta]
  • Chain C, Complex Of Enzyme Iiamannose And The Histidine-Containing Phosphocarrier Protein Hpr From Escherichia Coli Nmr, Restrained Regularized Mean Structure [nr-271106-contam.fasta]
  • Chain , Phosphotransferase (Histidine-Containing Phosphocarrier Protein) (Hpr) [nr-271106-contam.fasta]
  • Phosphocarrier protein HPr OS=Escherichia coli (strain K12) GN=ptsH PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 85 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFQQEVTITA PNGLHTRPAA QFVKEAKGFT SEITVTSNGK SASAKSLFKL QTLGLTQGTV  60
   61 VTISAEGEDE QKAVEHLVKL MAELE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] PSI-BLAST 24.522879 Histidine-containing phosphocarrier protein (HPr)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
    		•  5.70778264466435 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  4.7398246519874 bayes_pls_golite062009
  • transporter activity
    		•  1.94557075462337 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.8285077384404 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.73790085561506 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.57976971135135 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.4723961195197 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.97685688328333 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.61783246115451 bayes_pls_golite062009
  • binding
    		•  0.569728786489819 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle