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Protein Overview: NUOF_ECOLI

General Information:
Name(s) found: NUOF_ECOLI [Swiss-Prot]
Description(s) found:
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  • pir||B65000 NADH2 dehydrogenase (ubiquinone) (EC 1.6.5.3) I chain F - Escherichia coli (strain K-12) [NCBI NR]
  • gi|2506953|sp|P31979.3|NUOF_ECOLI RecName: Full=NADH-quinone oxidoreductase subunit F; AltName: Full=NADH dehydrogenase I subunit F; AltName: Full=NDH-1 subunit F; AltName: Full=NUO6 [NCBI NR]
  • dbj|BAA16118.1| NADH DEHYDROGENASE I CHAIN F (EC 1.6.5.3) (NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 6) (NUO6). [Escherichia coli] [NCBI NR]
  • gi|1799645|dbj|BAA16113.1| NADH:ubiquinone oxidoreductase, chain F [Escherichia coli W3110] [NCBI NR]
  • NADH-quinone oxidoreductase chain F (EC 1.6.99.5) (NADH dehydrogenase I, chain F) (NDH-1, chain F) (NUO6) - Escherichia coli [Swiss-Prot]
  • NADH dehydrogenase I chain F [Escherichia coli K12]gi|1788620|gb|AAC75344.1| NADH dehydrogenase I chain F [Escherichia coli K12]gi|7427775|pir||B65000 NADH2 dehydrogenase (ubiquinone) (EC 1.6.5.3) I chain F - Escherichia coli (strain K-12)gi|2506953|sp [nrdb_11152004_Chlamydomonas]
  • NADH-quinone oxidoreductase subunit F (NADH dehydrogenase I subunit F) (NDH-1 subunit F) (NUO6) [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • NADH-quinone oxidoreductase subunit F OS=Escherichia coli (strain K12) GN=nuoF PE=1 SV=3 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 445 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNIIRTPET HPLTWRLRDD KQPVWLDEYR SKNGYEGARK ALTGLSPDEI VNQVKDAGLK  60
   61 GRGGAGFSTG LKWSLMPKDE SMNIRYLLCN ADEMEPGTYK DRLLMEQLPH LLVEGMLISA 120
  121 FALKAYRGYI FLRGEYIEAA VNLRRAIAEA TEAGLLGKNI MGTGFDFELF VHTGAGRYIC 180
  181 GEETALINSL EGRRANPRSK PPFPATSGAW GKPTCVNNVE TLCNVPAILA NGVEWYQNIS 240
  241 KSKDAGTKLM GFSGRVKNPG LWELPFGTTA REILEDYAGG MRDGLKFKAW QPGGAGTDFL 300
  301 TEAHLDLPME FESIGKAGSR LGTALAMAVD HEINMVSLVR NLEEFFARES CGWCTPCRDG 360
  361 LPWSVKILRA LERGEGQPGD IETLEQLCRF LGPGKTFCAH APGAVEPLQS AIKYFREEFE 420
  421 AGIKQPFSNT HLINGIQPNL LKERW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..445] PSI-BLAST 152.0 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  13.4136491947011 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  12.443012098477 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  12.1743193111446 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  11.5132141901667 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  10.8948060301507 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.75377893144873 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  5.81993873720697 bayes_pls_golite062009
  • formate dehydrogenase activity
    		•  5.21374407932502 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  4.82023808325158 bayes_pls_golite062009
  • metal cluster binding
    		•  4.82023808325158 bayes_pls_golite062009
  • electron carrier activity
    		•  2.54863993527021 bayes_pls_golite062009
  • catalytic activity
    		•  1.46362311772849 bayes_pls_golite062009
  • binding
    		•  1.28125949803588 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor
    		•  0.530794334701446 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.471058486160512 bayes_pls_golite062009
  • ferredoxin hydrogenase activity
    		•  0.281674499766589 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
    		•  0.281674499766589 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle