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Protein Overview: Nach-PB

General Information:
Name(s) found: Nach-PB / FBpp0088960 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene Nach is referred to in FlyBase by the symbol Dmel\Nach (CG8178, FBgn0024319). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12540710..12542551. It has the cytological map location 53C14. It is reported to have molecular function</span>: sodium channel activity. There is experimental evidence that it is involved in the biological process</span>: liquid clearance, open tracheal system. 5 alleles are reported. The phenotype of these alleles is annotated with: adult tracheal system. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 535 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [NAS]
    Biological Process: sodium ion transport [IEA]
    liquid clearance, open tracheal system [IMP]
    Molecular Function: sodium channel activity [IEA][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGHQEELKPE QVDLKVTPFV GYLRRTWSDF CATSSIHGLK YTRDEDTNKI VHLVWLLISV  60
   61 VMFICAVVMA RTFYMDYRSS PTRMNVESDN TPVNRLYFPP VTICPDVLFN MQKSEAFLNT 120
  121 LRLPKGAELR GILRKLHIFY GFMLDDERYS AEDIEQMEAL LFLNNLTIPE FVEHLRWNCD 180
  181 EILYRCRFNG EIMDCSKIFQ LSKTFFGHCC SFNLRQKGWV NNKLNNLESF KVFHLNSLNF 240
  241 TAQRAIGGLR YGLSVVVRYK DDNYDPLQSY SYGVKLLIQE ADAFPSAHSA AKFIAFNSET 300
  301 FAAVRPQETF CSSAVKALII EERNCVFQNE FPMRYFSDYV YPNCELNCRV TNMVKFCGCH 360
  361 TYFFDFNRTS DRICTFRDIP CLVDNFANII TRKKSTQCYC PLTCEHIDYD VQLTNFPLEL 420
  421 NMPVADKFYS GLAKNDGVLH VFINSFSYRR LRRDLLSNMV TLVSNLGSAF SLFVGMSMLS 480
  481 VVEIIYYFSV ILRKNYKLEC ETRSQMLHKK PKFAWPKAND THSKEQKSVF IIHKS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..535] PSI-BLAST 100.0 No description for 2qtsA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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