Protein Overview: IL3_RAT

General Information:
Name(s) found:	IL3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|S07369 interleukin-3 precursor - rat [NCBI NR] gi\|1763673\|gb\|AAC17705.1\| interleukin-3 alpha [Rattus norvegicus] [NCBI NR] gi\|124334\|sp\|P04823.1\|IL3_RAT RecName: Full=Interleukin-3; Short=IL-3; AltName: Full=Multipotential colony-stimulating factor; AltName: Full=Hematopoietic growth factor; AltName: Full=P-cell-stimulating factor; AltName: Full=Mast cell growth factor; Short [NCBI NR] Interleukin-3 OS=Rattus norvegicus GN=Il3 PE=2 SV=1 [Swiss-Prot] interleukin-3 precursor - ratgi\|1763673\|gb\|AAC17705.1\| interleukin-3 alpha [Rattus norvegicus]gi\|124334\|sp\|P04823\|IL3_RAT Interleukin-3 precursor (IL-3) (Multipotential colony-stimulating factor) (Hematopoietic growth factor) (P-cell stimulating factor) [nrdb_11152004_Chlamydomonas] Interleukin-3 precursor (IL-3) (Multipotential colony-stimulating factor) (Hematopoietic growth factor) (P-cell-stimulating factor) (Mast cell growth factor) (MCGF) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] interleukin-3 alpha [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Interleukin-3 precursor (IL-3) (Multipotential colony-stimulating factor) (Hematopoietic growth factor) (P-cell-stimulating factor) (Mast-cell growth factor) (MCGF) [nr-271106-contam.fasta]
Organism:	Rattus norvegicus
Length:	166 amino acids
Gene Ontology:
Cellular Component:	extracellular space [UNKNOWN][IDA] extracellular region [IEA]
Biological Process:	hemopoiesis [IMP] positive regulation of cell proliferation [UNKNOWN][IDA][IMP] positive regulation of survival gene product expression [UNKNOWN][IEA] positive regulation of DNA replication [UNKNOWN] response to hormone stimulus [IMP] positive regulation of tyrosine phosphorylation of Stat5 protein [UNKNOWN] positive regulation of myeloid leukocyte differentiation [UNKNOWN][IEA] immune response [IEA] regulation of cell growth [IMP] negative regulation of autophagy [UNKNOWN][IEA] cytokine-mediated signaling pathway [UNKNOWN][IEA] negative regulation of apoptosis [UNKNOWN][IEA] positive regulation of JNK cascade [UNKNOWN][IEA] positive regulation of protein amino acid phosphorylation [UNKNOWN] regulation of gene expression [UNKNOWN][IEA] negative regulation of mast cell apoptosis [UNKNOWN][IEA] positive regulation of peptidyl-tyrosine phosphorylation [UNKNOWN][IEA] myeloid cell apoptosis [UNKNOWN][IEA] positive regulation of mast cell proliferation [UNKNOWN][IEA]
Molecular Function:	growth factor activity [UNKNOWN][IEA] protein binding [UNKNOWN] cytokine activity [UNKNOWN][IDA][IMP] interleukin-3 receptor binding [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLASSTTSI LCMLLPLLML FHQGLQISDR GSDAHHLLRT LDCRTIALEI LVKLPVSGLN  60
   61 NSDDKANLRN STLRRVNLDE FLKSQEEFDS QDTTDIKSKL QKLKCCIPAA ASDSVLPGVY 120
  121 NKDLDDFKKK LRFYVIHLKD LQPVSVSRPP QPTSSSDNFR PMTVEC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: IL3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: