Protein Overview: gcm2-PB

General Information:
Name(s) found:	gcm2-PB / FBpp0089223 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|45552293\|ref\|NP_995669.1\| gcm2, isoform B [Drosophila melanogaster] [NCBI NR] gi\|45445064\|gb\|AAS64666.1\| gcm2, isoform B [Drosophila melanogaster] [NCBI NR] gi\|34222660\|sp\|Q9VLA2.3\|GCM2_DROME RecName: Full=Transcription factor glial cells missing 2; AltName: Full=Protein glide-2 [NCBI NR] Transcription factor glial cells missing 2 OS=Drosophila melanogaster GN=gcm2 PE=2 SV=3 [Swiss-Prot] The gene gcm2 is referred to in FlyBase by the symbol Dmel\gcm2 (CG3858, FBgn0019809). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9608479..9612710. It has the cytological map location 30C1. There is experimental evidence that it has the molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: embryonic crystal cell differentiation; glial cell differentiation; cell proliferation; dendrite morphogenesis; glial cell development; negative regulation of crystal cell differentiation; gliogenesis; neuron differentiation; plasmatocyte differentiation. 8 alleles are reported. The phenotypes of these alleles are annotated with: crystal cell primordium; crystal cell. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] (Q9VLA2) Transcription factor glial cells missing 2 (Glide2 protein) [DrosMelano7227.FASTAC.txt] (AAS64666) CG3858-PB [DrosMelano7227.FASTAC.txt] (AE003625) glide2 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG3858-PB, isoform B [Drosophila melanogaster]gi\|45552293\|ref\|NP_995669.1\| CG3858-PB [Drosophila melanogaster]gi\|34222660\|sp\|Q9VLA2\|GCM2_DROME Transcription factor glial cells missing 2 (Glide2 protein) [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(9610570..9611346,9611412..9611502,9611562..9612535); ID=FBpp0089223; name=gcm2-PB; parent=FBgn0019809,FBtr0079838; dbxref=FlyBase:FBpp0089223,FlyBase_Annotation_IDs:CG3858-PB,GB_protein:AAS64666.1,REFSEQ:NP_995669,GB_protein:AAS6 [fly-100309-contam.fasta] gcm2 CG3858-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] Transcription factor glial cells missing 2 (Protein glide-2) [nr-271106-contam.fasta] CG3858-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(9610570..9611346,9611412..9611502,9611562..9612535); ID=FBpp0089223; name=gcm2-PB; parent=FBgn0019809,FBtr0079838; dbxref=FlyBase:FBpp0089223,FlyBase_Annotation_IDs:CG3858-PB,GB_protein:AAS64666.1,REFSEQ:NP_995669,GB_protein:AAS64666; MD5=afae2e0b3b49446e2a8484d90582203b; length=613; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(9610570..9611346,9611412..9611502,9611562..9612535); ID=FBpp0089223; name=gcm2-PB; parent=FBgn0019809,FBtr0079838; dbxref=FlyBase:FBpp0089223,FlyBase_Annotation_IDs:CG3858-PB,GB_protein:AAS64666.1,REFSEQ:NP_995669,GB_protein:AAS64666; MD5=afae2e0b3b49446e2a8484d90582203b; length=613; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2L:join(9610570..9611346,9611412..9611502,9611562..9612535); ID=FBpp0089223; name=gcm2-PB; parent=FBgn0019809,FBtr0079838; dbxref=FlyBase:FBpp0089223,FlyBase_Annotation_IDs:CG3858-PB,GB_protein:AAS64666.1,REFSEQ:NP_995669,GB_protein:AAS64666,FlyMine:FBpp0089223,modMine:FBpp0089223; MD5=afae2e0b3b49446e2a8484d90582203b; length=613; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
Organism:	Drosophila melanogaster
Length:	613 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS]
Biological Process:	cell proliferation [IMP] embryonic crystal cell differentiation [IMP] gliogenesis [IGI][IMP] negative regulation of crystal cell differentiation [IMP] neuron differentiation [IMP] embryonic plasmatocyte differentiation [TAS] regulation of transcription, DNA-dependent [IEA] plasmatocyte differentiation [IEP][IMP][TAS] glial cell development [IMP] glial cell differentiation [IGI][IMP] [NOT]crystal cell differentiation [IMP] dendrite morphogenesis [IMP]
Molecular Function:	DNA binding [ISS] transcription factor activity [IDA][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLIIYKILY RNGYSFKTQQ LLTQQPDHSQ LTQFVQPQSQ STHSVHPGPS PGQQQAGGSM  60
   61 TMPSSSTGKG KREWDINDAI VPHVPDQEFD EFNEWSDGHV RHIYSLHNEE AKKHISGWAM 120
  121 RNTNNHNVNI LKKSCLGVLV CSQHCTLPNG SKINLRPAIC DKARRKQEGK ACPNKSCRGG 180
  181 RLEIKPCRGH CGYPVTHFWR HSGNAIFFQA KGVHDHLRPD PKNSSVSKRA FGRVPLAGKS 240
  241 ANGSVAKKSV IAGLVKQAKQ QHSLISKVLK RPAVSNPLAH TALDIYQYNA CGKCAGYSHC 300
  301 TCSYLDDSTT ARSHQLSQSS NYGTNSWPLS GSESSAPCET AANVFTVNHQ HITYNYPIYH 360
  361 ATPAAATAAP SKSPSLPYAC SISELAAYQQ SSSGNSFAMG VPVHGHTQCQ AVAYDSSPQL 420
  421 ATPEPEFINY SQIKHLGGGG GQEEISCKAE PGPTIKYNAT VETQPYVEDN YDYYYSPKAE 480
  481 YEMQQHHHQQ QQSHQQFGGN QTAGHHYYES SSGYNGVSYF DTGTTTAPGN TATGNGLEVG 540
  541 YGGYYDHYTS YEQQMAVAGG FATAGGSTAP TVAAPPGHPP PPPPPPTLTY HHHHHHHLHH 600
  601 PAAATGLAPS VTH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: gcm2-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: