Protein Overview: ADAR

General Information:
Name(s) found:	ADAR [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|915284\|gb\|AAC13782.1\| p136 [Homo sapiens] [NCBI NR] ref\|NP_001102.1\| adenosine deaminase, RNA-specific isoform ADAR-a [Homo sapiens] [NCBI NR] gi\|38372880\|sp\|P55265\|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4) [NCBI NR] gi\|2795791\|gb\|AAB97118.1\| RNA adenosine deaminase [Homo sapiens] [NCBI NR] adenosine deaminase, RNA-specific [HGNC (HUGO)] (P55265) Double-stranded RNA-specific adenosine deaminase (EC 3.5.4.-) (DRADA) (136 kDa double-stranded RNA binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein) [Swiss-Prot] Double-stranded RNA-specific adenosine deaminase - Homo sapiens (Human) [Swiss-Prot] adenosine deaminase, RNA-specific isoform ADAR-a [HMR_022704.fasta] adenosine deaminase, RNA-specific isoform ADAR-a [Homo sapiens]gi\|915284\|gb\|AAC13782.1\| p136gi\|2795791\|gb\|AAB97118.1\| RNA adenosine deaminase [Homo sapiens]gi\|38372880\|sp\|P55265\|DSRA_HUMAN Double-stranded RNA-specific adenosine deaminase (DRADA) (136 k [nrdb_11152004_Chlamydomonas] Double-stranded RNA-specific adenosine deaminase (DRADA) (136 kDa double-stranded RNA binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Splice Isoform 1 of Double-stranded RNA-specific adenosine deaminase [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] (NM_001111) adenosine deaminase, RNA-specific, isoform ADAR-a [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] p136 [Homo sapiens] [NCBI-RefSeq_human_na_05-03-2007_con_reversed.fasta] adenosine deaminase, RNA-specific isoform ADAR-a [Homo sapiens] [HumanGallus06162005.fasta] Double-stranded RNA-specific adenosine deaminase (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] RNA adenosine deaminase [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Isoform 1 of Double-stranded RNA-specific adenosine deaminase [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] RecName: Full=Double-stranded RNA-specific adenosine deaminase; Short=DRADA; AltName: Full=136 kDa double-stranded RNA-binding protein; AltName: Full=P136; AltName: Full=K88DSRBP; AltName: Full=Interferon-inducible protein 4; Short=IFI-4 [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta] Double-stranded RNA-specific adenosine deaminase (DRADA) (136 kDa double-stranded RNA-binding protein) (P136) (K88DSRBP) (Interferon-inducible protein 4) (IFI-4 protein) [nr-271106-contam.fasta] Tax_Id=9606 Gene_Symbol=ADAR Isoform 1 of Double-stranded RNA-specific adenosine deaminase [EBI-IPI_human_3.30_06-28-2007_con_reversed.fasta]
Organism:	Homo sapiens
Length:	1226 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPRQGYSLS GYYTHPFQGY EHRQLRYQQP GPGSSPSSFL LKQIEFLKGQ LPEAPVIGKQ  60
   61 TPSLPPSLPG LRPRFPVLLA SSTRGRQVDI RGVPRGVHLG SQGLQRGFQH PSPRGRSLPQ 120
  121 RGVDCLSSHF QELSIYQDQE QRILKFLEEL GEGKATTAHD LSGKLGTPKK EINRVLYSLA 180
  181 KKGKLQKEAG TPPLWKIAVS TQAWNQHSGV VRPDGHSQGA PNSDPSLEPE DRNSTSVSED 240
  241 LLEPFIAVSA QAWNQHSGVV RPDSHSQGSP NSDPGLEPED SNSTSALEDP LEFLDMAEIK 300
  301 EKICDYLFNV SDSSALNLAK NIGLTKARDI NAVLIDMERQ GDVYRQGTTP PIWHLTDKKR 360
  361 ERMQIKRNTN SVPETAPAAI PETRRNAEFL TCNIPTSNAS NNMVTTEKVE NGQEPVIKLE 420
  421 NRQEARPEPA RLKPPVHYNG PSKAGYVDFE NGQWATDDIP DDLNSIRAAP GEFRAIMEMP 480
  481 SFYSHGLPRC SPYKKLTECQ LKNPISGLLE YAQFASQTCE FNMIEQSGPP HEPRFKFQVV 540
  541 INGREFPPAE AGSKKVAKQD AAMKAMTILL EEAKAKDSGK SEESSHYSTE KESEKTAESQ 600
  601 TPTPSATSFF SGKSPVTTLL ECMHKLGNSC EFRLLSKEGP AHEPKFQYCV AVGAQTFPSV 660
  661 SAPSKKVAKQ MAAEEAMKAL HGEATNSMAS DNQPEGMISE SLDNLESMMP NKVRKIGELV 720
  721 RYLNTNPVGG LLEYARSHGF AAEFKLVDQS GPPHEPKFVY QAKVGGRWFP AVCAHSKKQG 780
  781 KQEAADAALR VLIGENEKAE RMGFTEVTPV TGASLRRTML LLSRSPEAQP KTLPLTGSTF 840
  841 HDQIAMLSHR CFNTLTNSFQ PSLLGRKILA AIIMKKDSED MGVVVSLGTG NRCVKGDSLS 900
  901 LKGETVNDCH AEIISRRGFI RFLYSELMKY NSQTAKDSIF EPAKGGEKLQ IKKTVSFHLY 960
  961 ISTAPCGDGA LFDKSCSDRA MESTESRHYP VFENPKQGKL RTKVENGEGT IPVESSDIVP1020
 1021 TWDGIRLGER LRTMSCSDKI LRWNVLGLQG ALLTHFLQPI YLKSVTLGYL FSQGHLTRAI1080
 1081 CCRVTRDGSA FEDGLRHPFI VNHPKVGRVS IYDSKRQSGK TKETSVNWCL ADGYDLEILD1140
 1141 GTRGTVDGPR NELSRVSKKN IFLLFKKLCS FRYRRDLLRL SYGEAKKAAR DYETAKNYFK1200
 1201 KGLKDMGYGN WISKPQEEKN FYLCPV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	gi\|14317902, gi\|...	No Comments	Cheeseman, I.M., et al. (2004)
View Run	MIS12	No Comments	Cheeseman, I.M., et al. (2004)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: ADAR

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: