Protein Overview: CPSF2

General Information:
Name(s) found:	CPSF2 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|51338827\|sp\|Q9P2I0.2\|CPSF2_HUMAN RecName: Full=Cleavage and polyadenylation specificity factor subunit 2; AltName: Full=Cleavage and polyadenylation specificity factor 100 kDa subunit; Short=CPSF 100 kDa subunit [NCBI NR] gi\|34101288\|ref\|NP_059133.1\| cleavage and polyadenylation specific factor 2 [Homo sapiens] [NCBI NR] gi\|193786082\|dbj\|BAG50953.1\| unnamed protein product [Homo sapiens] [NCBI NR] gi\|119601888\|gb\|EAW81482.1\| cleavage and polyadenylation specific factor 2, 100kDa, isoform CRA_a [Homo sapiens] [NCBI NR] gi\|119601886\|gb\|EAW81480.1\| cleavage and polyadenylation specific factor 2, 100kDa, isoform CRA_a [Homo sapiens] [NCBI NR] cleavage and polyadenylation specific factor 2, 100kDa [HGNC (HUGO)] Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens GN=CPSF2 PE=1 SV=2 [Swiss-Prot] (Q9P2I0) Cleavage and polyadenylation specificity factor, 100 kDa subunit (CPSF 100 kDa subunit) [Swiss-Prot] cleavage and polyadenylation specific factor 2; cleavage and polyadenylation specificity factor, 100kD subunit; CPSF 100kDa subunit [HMR_022704.fasta] cleavage and polyadenylation specific factor 2; cleavage and polyadenylation specificity factor, 100kD subunit; CPSF 100kDa subunit; cleavage and polyadenylation specific factor 2, 100kD subunit [071204_hmrz_cont.fasta] cleavage and polyadenylation specific factor 2 [Homo sapiens]gi\|51338827\|sp\|Q9P2I0\|CPSB_HUMAN Cleavage and polyadenylation specificity factor, 100 kDa subunit (CPSF 100 kDa subunit) [nrdb_11152004_Chlamydomonas] Cleavage and polyadenylation specificity factor, 100 kDa subunit (CPSF 100 kDa subunit) [Yateslab_human_na_07-28-2006_reversed.fasta] Tax_Id=9606 Cleavage and polyadenylation specificity factor, 100 kDa subunit [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] QP2I0\| Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit) (aka CPFS1000) [Homo Sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] cleavage and polyadenylation specific factor 2 [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta] cleavage and polyadenylation specific factor 2; cleavage and polyadenylation specificity factor, 100kD subunit; CPSF 100kDa subunit; cleavage and polyadenylation specific factor 2, 100kD subunit [Homo sapiens] [HumanGallus06162005.fasta] cleavage and polyadenylation specific factor 2; cleavage and polyadenylation specificity factor, 100kD subunit; CPSF 100kDa subunit [Homo sapiens] [human-NCBI-042104-rand.fasta] unnamed protein product [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (CPSF 100 kDa subunit) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] cleavage and polyadenylation specific factor 2, 100kDa, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Tax_Id=9606 Cleavage and polyadenylation specificity factor 100 kDa subunit [EBI-IPI_human_3.23_11-02-2006_con_reversed.fasta] Tax_Id=9606 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR, 100 KDA SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=9606 Gene_Symbol=CPSF2 Cleavage and polyadenylation specificity factor subunit 2 [human-ipi-250309-contam.fasta] Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF 100 kDa subunit) [nr-271106-contam.fasta] IPI:IPI00419531.2\|SWISS-PROT:Q9P2I0\|TREMBL:B3KME1;B3KN45\|ENSEMBL:ENSP00000298875\|REFSEQ:NP_059133\|H-INV:HIT000004101\|VEGA:OTTHUMP00000028341 Tax_Id=9606 Gene_Symbol=CPSF2 Cleavage and polyadenylation specificity factor subunit 2 [ipi.HUMAN.fasta.20090807] Tax_Id=9606 Cleavage and polyadenylation specificity factor subunit 2 [IPI_human_3.26.fasta] [human_BMb_040710_contam.fasta] Tax_Id=9606 Gene_Symbol=CPSF2 Cleavage and polyadenylation specificity factor subunit 2 ENSG00000165934 IPI00419531 [drosphohumanreversed.fasta] cleavage and polyadenylation specificity factor subunit 2 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Q9P2I0;B3KME1;Q6NSJ1;Q9H3W7; RecName: Full=Cleavage and polyadenylation specificity factor subunit 2; AltName: Full=Cleavage and polyadenylation specificity factor 100 kDa subunit; [UniProt_Human_2010_06_06-01-2010_reversed.fasta] Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens GN=CPSF2 [011711_HMR.fasta] IPI:IPI00419531.2\|SWISS-PROT:Q9P2I0\|TREMBL:B3KN45\|ENSEMBL:ENSP00000298875\|REFSEQ:NP_059133\|H-INV:HIT000004101\|VEGA:OTTHUMP00000028341 Tax_Id=9606 Gene_Symbol=CPSF2 Cleavage and polyadenylation specificity factor subunit 2 [ipi.HUMAN.fasta.20100406] Cleavage and polyadenylation specificity factor subunit 2 n=20 Tax=Tetrapoda RepID=CPSF2_HUMAN [UniProt_Xenopus_laevis_01-01-2011_reversed.fasta] GeneSymbol=CPSF2 Synonyms=CPSF100\|KIAA1367 cleavage and polyadenylation specificity factor subunit 2 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta] IPI:IPI00419531.2\|SWISS-PROT:Q9P2I0\|TREMBL:B3KN45\|ENSEMBL:ENSP00000298875\|REFSEQ:NP_059133\|H-INV:HIT000004101 Tax_Id=9606 Gene_Symbol=CPSF2 Cleavage and polyadenylation specificity factor subunit 2 [ipi.HUMAN.20110912.fasta] Cleavage and polyadenylation specificity factor subunit 2 GN=CPSF2 [Doctor+uniprot-HUMAN-120911.fasta] Cleavage and polyadenylation specific factor 2, 100kDa, isoform CRA_a OS=Homo sapiens GN=CPSF2 PE=4 SV=1 [uniprot-human-031015-contam.fasta]
Organism:	Homo sapiens
Length:	782 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSIIKLTTL SGVQEESALC YLLQVDEFRF LLDCGWDEHF SMDIIDSLRK HVHQIDAVLL  60
   61 SHPDPLHLGA LPYAVGKLGL NCAIYATIPV YKMGQMFMYD LYQSRHNTED FTLFTLDDVD 120
  121 AAFDKIQQLK FSQIVNLKGK GHGLSITPLP AGHMIGGTIW KIVKDGEEEI VYAVDFNHKR 180
  181 EIHLNGCSLE MLSRPSLLIT DSFNATYVQP RRKQRDEQLL TNVLETLRGD GNVLIAVDTA 240
  241 GRVLELAQLL DQIWRTKDAG LGVYSLALLN NVSYNVVEFS KSQVEWMSDK LMRCFEDKRN 300
  301 NPFQFRHLSL CHGLSDLARV PSPKVVLASQ PDLECGFSRD LFIQWCQDPK NSIILTYRTT 360
  361 PGTLARFLID NPSEKITEIE LRKRVKLEGK ELEEYLEKEK LKKEAAKKLE QSKEADIDSS 420
  421 DESDIEEDID QPSAHKTKHD LMMKGEGSRK GSFFKQAKKS YPMFPAPEER IKWDEYGEII 480
  481 KPEDFLVPEL QATEEEKSKL ESGLTNGDEP MDQDLSDVPT KCISTTESIE IKARVTYIDY 540
  541 EGRSDGDSIK KIINQMKPRQ LIIVHGPPEA SQDLAECCRA FGGKDIKVYM PKLHETVDAT 600
  601 SETHIYQVRL KDSLVSSLQF CKAKDAELAW IDGVLDMRVS KVDTGVILEE GELKDDGEDS 660
  661 EMQVEAPSDS SVIAQQKAMK SLFGDDEKET GEESEIIPTL EPLPPHEVPG HQSVFMNEPR 720
  721 LSDFKQVLLR EGIQAEFVGG VLVCNNQVAV RRTETGRIGL EGCLCQDFYR IRDLLYEQYA 780
  781 IV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..453]	PSI-BLAST	84.39794	No description for 2i7tA was found.
2	View Details	[454..662]	FFAS03	3.21	No description for 2i7xA was found.
3	View Details	[663..782]	deduced	N/A	No confident structure predictions are available.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.86

Protein Overview: CPSF2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: