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Protein Overview: sli-1

General Information:
Name(s) found: sli-1 / CE37131 [WormBase]
Description(s) found:
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  • WBGene00004829 locus:sli-1 status:Partially_confirmed UniProt:Q6ABG8 protein_id:CCD62723.1 [WormBase]
  • gi|71993905|ref|NP_001024798.1| Suppressor of LIneage defect family member (sli-1) [Caenorhabditis elegans] [NCBI NR]
  • gi|51011296|gb|AAT92069.1| Suppressor of lineage defect protein 1, isoform c, partially confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR]
  • Suppressor of lineage defect protein 1, isoform c [Caenorhabditis elegans] [nrdb_11152004_Chlamydomonas]
  • CE37131 WBGene00004829 locus:sli-1 status:Partially_confirmed TR:Q6ABG8 protein_id:AAT92069.1 [wormpep150.fasta]
  • 37131 WBGene00004829 locus:sli-1 status:Partially_confirmed protein_id:AAT92069.1 [wormpep130-phg-ecoli-orf-rand.fasta]
  • 37131 WBGene00004829 locus:sli-1 status:Partially_confirmed TR:Q6ABG8 protein_id:AAT92069.1 [wormpep150-phg-orf-ecoli-rand.fasta]
  • CE37131 WBGene00004829 locus:sli-1 status:Partially_confirmed UniProt:Q6ABG8_CAEEL protein_id:AAT92069.1 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta]
  • CE37131 WBGene00004829 locus:sli-1 status:Partially_confirmed UniProt:Q6ABG8_CAEEL protein_id:AAT92069.1| [wormORF-contam.fasta]
  • Suppressor of LIneage defect family member (sli-1) [Caenorhabditis elegans] [nr-271106-contam.fasta]
  • CE37131 WBGene00004829 locus:sli-1 status:Partially_confirmed UniProt:Q6ABG8 protein_id:AAT92069.1 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta]
  • [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr]
  • CE37131 WBGene00004829 locus:sli-1 status:Partially_confirmed UniProt:Q6ABG8 protein_id:CCD62723.1 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta]
  • Isoform of Q19019, Suppressor of LIneage defect OS=Caenorhabditis elegans GN=sli-1 PE=4 SV=1 [CAEEL.fasta.20160308]
    • Organism: Caenorhabditis elegans
    Length: 523 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEALink to PubMed article]
    Biological Process: cell surface receptor linked signaling pathway [IEALink to PubMed article]
    Molecular Function: zinc ion binding [IEALink to PubMed article]
    protein binding [IEALink to PubMed article]
    calcium ion binding [IEALink to PubMed article]
    signal transducer activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSINTIFHR IHRFVNGTGN NARFVPSTNN STEALTLSPR AVPSTVSDRR FLLKACKFMD  60
   61 QVVKSCHSPR LNLKNSPPFI LDILPDTYTH LMLIFTQNND ILQDNDYLKI FLESMINKCK 120
  121 EIIKLFKTSA IYNDQSEERR KLTKMSLTFS HMLFEIKALF PEGIYIEDRF RMTKKEAESF 180
  181 WSHHFTKKNI VPWSTFFTAL EKHHGSTIGK MEAAELKATI DLSGDDFISN FEFDVFTRLF 240
  241 YPFKTLIKNW QTLTTAHPGY CAFLTYDEVK KRLEKLTKKP GSYIFRLSCT RPGQWAIGYV 300
  301 APDGKIYQTI PQNKSLIQAL HEGHKEGFYI YPNGRDQDIN LSKLMDVPQA DRVQVTSEQY 360
  361 ELYCEMGTTF ELCKICDDNE KNIKIEPCGH LLCAKCLANW QDSDGGGNTC PFCRYEIKGT 420
  421 NRVIIDRFKP TPVEIEKAKN VAAAEKKLIS LVPDVPPRTS SQTSSSYVNI KELENVETSG 480
  481 EALAQVVNRQ RAPSIQAPPL PPRLSASEHQ PHHPYTNTNS ERE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..427] PSI-BLAST 123.0 Cbl; N-terminal domain of cbl (N-cbl); CBL
    2 View Details [428..523] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.78762232945822 bayes_pls_golite062009
  • protein binding
    		•  1.4273874265634 bayes_pls_golite062009
  • signal transducer activity
    		•  1.37370552536239 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.37370552536239 bayes_pls_golite062009
  • epidermal growth factor receptor binding
    		•  1.03934535504406 bayes_pls_golite062009
  • molecular adaptor activity
    		•  0.58947294551094 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  0.52889761132084 bayes_pls_golite062009
  • calcium ion binding
    		•  0.292797014921594 bayes_pls_golite062009
  • insulin receptor binding
    		•  0.28737567192381 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.253080312769269 bayes_pls_golite062009
  • receptor binding
    		•  0.24683439420295 bayes_pls_golite062009
  • kinase activity
    		•  0.246780195377285 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.16106219404884 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.0904972759345899 bayes_pls_golite062009
  • hydrolase activity
    		•  0.062117874431973 bayes_pls_golite062009
  • protein kinase activity
    		•  0.0337037979217971 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle