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Protein Overview: HOP2

General Information:
Name(s) found: HOP2 / YGL033W [SGD]
Description(s) found:
Found 8 descriptions.
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  • Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 185 amino acids

    Gene Ontology:
    Cellular Component: condensed nuclear chromosome [IDALink to PubMed article]
    Biological Process: reciprocal meiotic recombination [IMPLink to PubMed article]
    synapsis [IMPLink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    double-stranded DNA binding [IDALink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALYRFGPNL HNKVTKTTAT KALENLVNEK RIVSKTFGKI IIYSCNEQDT ALPSNIDPSQ  60
   61 FDFETVLQLR NDLIELERDK STAKDALDSV TKEPENEDLL TIIENEENEL KKIESKLQSL 120
  121 QDDWDPANDE IVKRIMSEDT LLQKEITKRS KICKNLIATI KDSVCPKNMN EFLVCILNIF 180
  181 RDLFF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..185] ORFEUS 7.07 Outer surface protein C (OspC)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle