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Protein Overview: HMT2_ARATH

General Information:
Name(s) found: HMT2_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|7523407|emb|CAB86426.1| homocysteine S-methyltransferase AtHMT-2 [Arabidopsis thaliana] [NCBI NR]
  • gi|50400668|sp|Q9M1W4.1|HMT2_ARATH RecName: Full=Homocysteine S-methyltransferase 2; AltName: Full=S-methylmethionine:homocysteine methyltransferase 2; Short=SMM:Hcy S-methyltransferase 2; Short=AtHMT-2 [NCBI NR]
  • gi|33589736|gb|AAQ22634.1| At3g63250/F16M2_100 [Arabidopsis thaliana] [NCBI NR]
  • gi|16226446|gb|AAL16170.1|AF428402_1 AT3g63250/F16M2_100 [Arabidopsis thaliana] [NCBI NR]
  • gi|15229396|ref|NP_191884.1| HMT2 (HOMOCYSTEINE METHYLTRANSFERASE 2); homocysteine S-methyltransferase [Arabidopsis thaliana] [NCBI NR]
  • pir||T48114 homocysteine S-methyltransferase AtHMT-2 - Arabidopsis thaliana [NCBI NR]
  • gi|110743464|dbj|BAE99618.1| homocysteine S-methyltransferase AtHMT-2 [Arabidopsis thaliana] [NCBI NR]
  • Homocysteine S-methyltransferase 2 OS=Arabidopsis thaliana GN=HMT-2 PE=1 SV=1 [Swiss-Prot]
  • (Q9M1W4) Homocysteine S-methyltransferase AtHMT-2 (AT3g63250/F16M2_100) [athaliana3702.FASTAC.txt]
  • At3g63250/F16M2_100 [Arabidopsis thaliana]gi|7523407|emb|CAB86426.1| homocysteine S-methyltransferase AtHMT-2 [Arabidopsis thaliana]gi|16226446|gb|AAL16170.1| AT3g63250/F16M2_100 [Arabidopsis thaliana]gi|11357335|pir||T48114 homocysteine S-methyltransf [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Homocysteine S-methyltransferase 2 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: HMT-2, ATHMT-2, HMT2 | ATHMT-2/HMT-2/HMT2 (HOMOCYSTEINE METHYLTRANSFERASE 2); homocysteine S-methyltransferase | chr3:23381550-23383562 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • At3g63250/F16M2_100 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • homocysteine S-methyltransferase AtHMT-2 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Homocysteine S-methyltransferase 2 (S-methylmethionine:homocysteine methyltransferase 2) (SMM:Hcy S-methyltransferase 2) (AtHMT-2) [nr-271106-contam.fasta]
  • ATHMT-2/HMT-2; homocysteine S-methyltransferase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • AT3g63250/F16M2_100 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: HMT-2, ATHMT-2, HMT2 | homocysteine methyltransferase 2 | chr3:23370575-23372587 REVERSE LENGTH=333 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 333 amino acids

    Gene Ontology:
    Cellular Component: endomembrane system [IEA]
    Biological Process: methionine biosynthetic process [IDA]
    S-methylmethionine cycle [IMP]
    Molecular Function: homocysteine S-methyltransferase activity [IDA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGNSFNSMK DFLKQTGGYA VIDGGLATEF ERHGADLNDP LWSAKCLVTS PHLIHTVHLD  60
   61 YLEAGADIIS SASYQATIQG FEAKGFSREE SESLLKKSVE IATEARNSYY DKCGTSSSMD 120
  121 DKILKKRPIL VAASVGSYGA YLADGSEYSG IYGDSITLEK LKDFHRRRLQ VLAESGADLI 180
  181 AFETIPNKIE AQAFADLLEE GDVKIPGWFS FNSKDGVNVV SGDSIKECIS IAENCEKVVA 240
  241 VGINCTPPRF IEGLVLEIEK VTSKPILVYP NSGESYDADR KEWVENTGVG DEDFVSYVEK 300
  301 WMDAGVSLLG GCCRTTPTTI RAIHKRLVNR RSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..333] PSI-BLAST 77.045757 Cobalamin-dependent methionine synthase (MetH) from Thermotoga maritima (Oxidized, Monoclinic)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • S-methyltransferase activity
    		•  3.53817178180686 bayes_pls_golite062009
  • homocysteine S-methyltransferase activity
    		•  2.53321380120921 bayes_pls_golite062009
  • catalytic activity
    		•  1.41033217274476 bayes_pls_golite062009
  • transferase activity
    		•  0.499011632852061 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle