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Protein Overview: NDUV1_ARATH

General Information:
Name(s) found: NDUV1_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Arabidopsis thaliana GN=At5g08530 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 486 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex I [IDA]
    respiratory chain complex I [IDA]
    mitochondrion [IDA]
    Biological Process: mitochondrial electron transport, NADH to ubiquinone [ISS]
    Molecular Function: FMN binding [IEA]
    NAD or NADH binding [IEA]
    NADH dehydrogenase (ubiquinone) activity [IEA][ISS]
    4 iron, 4 sulfur cluster binding [IEA]
    oxidoreductase activity, acting on NADH or NADPH [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPVRGILGL QRAVSIWKES NRLTPALRSF STQAASTSTT PQPPPPPPPP EKTHFGGLKD  60
   61 EDRIFTNLYG LHDPFLKGAM KRGDWHRTKD LVLKGTDWIV NEMKKSGLRG RGGAGFPSGL 120
  121 KWSFMPKVSD GRPSYLVVNA DESEPGTCKD REIMRHDPHK LLEGCLIAGV GMRASAAYIY 180
  181 IRGEYVNERL NLEKARREAY AAGLLGKNAC GSGYDFEVYI HFGAGAYICG EETALLESLE 240
  241 GKQGKPRLKP PFPANAGLYG CPTTVTNVET VAVSPTILRR GPEWFSSFGR KNNAGTKLFC 300
  301 ISGHVNKPCT VEEEMSIPLK ELIERHCGGV RGGWDNLLAI IPGGSSVPLI PKNICEDVLM 360
  361 DFDALKAVQS GLGTAAVIVM DKSTDVVDAI ARLSYFYKHE SCGQCTPCRE GTGWLWMIME 420
  421 RMKVGNAKLE EIDMLQEVTK QIEGHTICAL GDAAAWPVQG LIRHFRPELE RRIRERAERE 480
  481 LLQAAA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..486] PSI-BLAST 151.0 Crystal structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NADH dehydrogenase activity
    		•  13.4136491947011 bayes_pls_golite062009
  • NADH dehydrogenase (ubiquinone) activity
    		•  12.443012098477 bayes_pls_golite062009
  • NADH dehydrogenase (quinone) activity
    		•  12.1743193111446 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  11.5132141901667 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  10.8948060301507 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.75377893144873 bayes_pls_golite062009
  • formate dehydrogenase activity
    		•  3.21486196088149 bayes_pls_golite062009
  • electron carrier activity
    		•  2.54863993527021 bayes_pls_golite062009
  • 4 iron, 4 sulfur cluster binding
    		•  2.15499718507114 bayes_pls_golite062009
  • catalytic activity
    		•  1.46362311772849 bayes_pls_golite062009
  • iron-sulfur cluster binding
    		•  1.25645944988955 bayes_pls_golite062009
  • metal cluster binding
    		•  1.25645944988955 bayes_pls_golite062009
  • binding
    		•  1.25265721111105 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor
    		•  0.530794334701446 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.471058486160512 bayes_pls_golite062009
  • ferredoxin hydrogenase activity
    		•  0.281674499766589 bayes_pls_golite062009
  • oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
    		•  0.281674499766589 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle