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Protein Overview: FOLM_ARATH

General Information:
Name(s) found: FOLM_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||T08976 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase (EC 2.7.6.3) - Arabidopsis thaliana [NCBI NR]
  • gi|7269900|emb|CAB80993.1| dihydropteroate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|4938476|emb|CAB43835.1| dihydropteroate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|192807342|gb|ACF06123.1| At4g30000 [Arabidopsis thaliana] [NCBI NR]
  • gi|15233801|ref|NP_194729.1| dihydropterin pyrophosphokinase, putative / dihydropteroate synthase, putative / DHPS, putative [Arabidopsis thaliana] [NCBI NR]
  • Folate synthesis bifunctional protein, mitochondrial OS=Arabidopsis thaliana GN=MitHPPK/DHPS PE=2 SV=1 [Swiss-Prot]
  • (Q9SZV3) Probable folate synthesis protein precursor [Includes: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) (HPPK); dihydropteroate synthase (EC 2.5.1.15) (DHPS)] [athaliana3702.FASTAC.txt]
  • dihydropteroate synthase-like protein [Arabidopsis thaliana]gi|4938476|emb|CAB43835.1| dihydropteroate synthase-like protein [Arabidopsis thaliana]gi|15233801|ref|NP_194729.1| dihydropterin pyrophosphokinase, putative / dihydropteroate synthase, putativ [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Dihydropterin pyrophosphokinase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: | dihydropterin pyrophosphokinase, putative / dihydropteroate synthase, putative / DHPS, putative | chr4:14670530-14672403 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase/ dihydropteroate synthase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • dihydropteroate synthase-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: | Dihydropterin pyrophosphokinase / Dihydropteroate synthase | chr4:14670524-14672397 REVERSE LENGTH=554 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • At4g30000 OS=Arabidopsis thaliana GN=F6G3.30 PE=2 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 554 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: folic acid and derivative biosynthetic process [IEA][ISS]
    cellular metabolic process [IEA]
    Molecular Function: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity [IEA]
    dihydropteroate synthase activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPLLSQTLI HTGRFLLRRF LEPPPAVISA VAASRVCFHR YYSSKSLSLV SPLGLHCSSL  60
   61 FSPPALCNSA FSSSATSTTI EVQSTEHEVV IALGSNIGNR MNNFREALRL MKRGGICVTR 120
  121 HSCLYETAPV HVTDQPRFLN AAVRGVTKLG PHELLSVLKT IERDMGRKDG IRYGPRPLDL 180
  181 DILFYGKMRI SSDKLIIPHE RLWERSFVLA PLVDLLGSAV DNDTVAHWHS LAIHPGGIFQ 240
  241 AWERLGGESL IGQDGIQRVL PIGDKLWDFS NKTHVMGILN LTPDSFSDGG KFQSIDSAVS 300
  301 RVRSMISEGA DIIDIGAQST RPMASRISSQ EELDRLLPVL EAVRGMPEME EKLISVDTFN 360
  361 SEVASEAISN GADILNDVSA GTLDPNMHKV VAESGVPYMA MHMRGDPCTM QNKENLQYDD 420
  421 VCKDVASELY LRVRDAELSG IPAWRVMIDP GIGFSKSVDH NLDIIMDLPK IREEMAKRSI 480
  481 AVSHAPILVG PSRKRFLGDI CGRPEATDRD AATVASVTAG ILGGANIIRV HNVRHNADAA 540
  541 KVCDAMLRRR RSKG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] PSI-BLAST 61.69897 No description for 2cg8A was found.
    2 View Details [86..554] PSI-BLAST 113.0 X-ray structure of the bifunctional 6-hydroxymethyl-7,8- dihydroxypterin pyrophosphokinase dihydropteroate synthase from Sacchromyces cerevisiae


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.64

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle