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Protein Overview: HCS1_ARATH

General Information:
Name(s) found: HCS1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|89000993|gb|ABD59086.1| At2g25710 [Arabidopsis thaliana] [NCBI NR]
  • gi|30682866|ref|NP_850067.1| HCS1 (HOLOCARBOXYLASE SYNTHASE); biotin-[acetyl-CoA-carboxylase] ligase/ catalytic [Arabidopsis thaliana] [NCBI NR]
  • gi|20197509|gb|AAD31371.2| biotin holocarboxylase synthetase [Arabidopsis thaliana] [NCBI NR]
  • gi|18400914|ref|NP_565605.1| HCS1 (HOLOCARBOXYLASE SYNTHASE); biotin-[acetyl-CoA-carboxylase] ligase/ catalytic [Arabidopsis thaliana] [NCBI NR]
  • gi|1688072|gb|AAC49706.1| biotin holocarboxylase synthetase [NCBI NR]
  • Biotin--protein ligase 1, chloroplastic OS=Arabidopsis thaliana GN=HCS1 PE=1 SV=2 [Swiss-Prot]
  • (Q9SL92) Biotin holocarboxylase synthetase (EC 6.3.4.10) [athaliana3702.FASTAC.txt]
  • biotin holocarboxylase synthetase [Arabidopsis thaliana]gi|1688072|gb|AAC49706.1| biotin holocarboxylase synthetasegi|18400914|ref|NP_565605.1| holocarboxylase synthetase 1 (HCS1) [Arabidopsis thaliana]gi|30682866|ref|NP_850067.1| holocarboxylase synth [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Holocarboxylase synthetase 1 (HCS1) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: HCS1 | HCS1 (HOLOCARBOXYLASE SYNTHASE); catalytic | chr2:10959797-10962139 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • biotin holocarboxylase synthetase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • HCS1 (HOLOCARBOXYLASE SYNTHASE); biotin-[acetyl-CoA-carboxylase] ligase/ catalytic [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At2g25710 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • biotin holocarboxylase synthetase [nr-271106-contam.fasta]
  • | Symbols: HCS1 | holocarboxylase synthase 1 | chr2:10952719-10955061 FORWARD LENGTH=367 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • At2g25710 OS=Arabidopsis thaliana GN=HCS1 PE=2 SV=2 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 367 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: protein modification process [IEA][ISS]
    Molecular Function: catalytic activity [IEA][ISS]
    biotin-[acetyl-CoA-carboxylase] ligase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAVRSTTTL SNFHLLNILV LRSLKPLHRL SFSFSASAME SDASCSLVLC GKSSVETEVA  60
   61 KGLKNKNSLK LPDNTKVSLI LESEAKNLVK DDDNSFNLSL FMNSIITHRF GRFLIWSPRL 120
  121 SSTHDVVSHN FSELPVGSVC VTDIQFKGRG RTKNVWESPK GCLMYSFTLE MEDGRVVPLI 180
  181 QYVVSLAVTE AVKDVCDKKG LPYIDVKIKW PNDLYVNGLK VGGILCTSTY RSKKFNVSVG 240
  241 VGLNVDNGQP TTCLNAVLKG MAPESNLLKR EEILGAFFHK FEKFFDLFMD QGFKSLEELY 300
  301 YRTWLHSEQR VIVEDKVEDQ VVQNVVTIQG LTSSGYLLAV GDDNQMYELH PDGNSFDFFK 360
  361 GLVRRKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..367] PSI-BLAST 77.0 THE E. COLI BIOTIN HOLOENZYME SYNTHETASE(SLASH)BIO REPRESSOR CRYSTAL STRUCTURE DELINEATES THE BIOTIN AND DNA-BINDING DOMAINS

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.46366406733797 bayes_pls_golite062009
  • ligase activity
    		•  1.22215897446525 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  0.92307591122679 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  0.92307591122679 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  0.92307153294189 bayes_pls_golite062009
  • DNA binding
    		•  0.3118855114645 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle