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Protein Overview: AB1B_ARATH

General Information:
Name(s) found: AB1B_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75338892|sp|Q9ZR72.1|AB1B_ARATH RecName: Full=ABC transporter B family member 1; Short=ABC transporter ABCB.1; Short=AtABCB1; AltName: Full=Multidrug resistance protein 1; AltName: Full=P-glycoprotein 1; Short=AtPgp1 [NCBI NR]
  • gi|4883607|gb|AAD31576.1| putative ABC transporter [Arabidopsis thaliana] [NCBI NR]
  • pir||A42150 P-glycoprotein pgp1 - Arabidopsis thaliana [NCBI NR]
  • gi|3849833|emb|CAA43646.1| P-glycoprotein [Arabidopsis thaliana] [NCBI NR]
  • gi|15228052|ref|NP_181228.1| ABCB1 (ATP BINDING CASSETTE SUBFAMILY B1); ATPase, coupled to transmembrane movement of substances / auxin efflux transmembrane transporter/ calmodulin binding [Arabidopsis thaliana] [NCBI NR]
  • Multidrug resistance protein 1 OS=Arabidopsis thaliana GN=MDR1 PE=1 SV=1 [Swiss-Prot]
  • ABC transporter B family member 1 OS=Arabidopsis thaliana GN=ABCB1 PE=1 SV=1 [Swiss-Prot]
  • (Q9ZR72) P-glycoprotein [athaliana3702.FASTAC.txt]
  • P-glycoprotein [Arabidopsis thaliana]gi|4883607|gb|AAD31576.1| putative ABC transporter [Arabidopsis thaliana]gi|15228052|ref|NP_181228.1| multidrug resistance P-glycoprotein (PGP1) [Arabidopsis thaliana]gi|419760|pir||A42150 P-glycoprotein pgp1 - Arab [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Multidrug resistance P-glycoprotein (PGP1) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: PGP1, ATMDR1 | ATPGP1 (ARABIDOPSIS THALIANA P GLYCOPROTEIN1); calmodulin binding | chr2:15509241-15514129 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative ABC transporter [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Multidrug resistance protein 1 (P-glycoprotein 1) (AtPgp1) [nr-271106-contam.fasta]
  • P-glycoprotein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATPGP1 (ARABIDOPSIS THALIANA P GLYCOPROTEIN1); calmodulin binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATPGP1, PGP1, ABCB1 | ATP binding cassette subfamily B1 | chr2:15502162-15507050 FORWARD LENGTH=1286 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 1286 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    Biological Process: auxin polar transport [IMP][TAS]
    response to red or far red light [IMP]
    positive gravitropism [IGI]
    photomorphogenesis [IMP]
    anthocyanin accumulation in tissues in response to UV light [IMP]
    stamen development [IGI]
    regulation of cell size [IMP]
    response to blue light [IMP]
    response to nematode [IEP]
    response to auxin stimulus [IMP]
    Molecular Function: ATPase activity, coupled to transmembrane movement of substances [ISS]
    calmodulin binding [ISS]
    auxin efflux transmembrane transporter activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNDGGAPPP PPTLVVEEPK KAEIRGVAFK ELFRFADGLD YVLMGIGSVG AFVHGCSLPL  60
   61 FLRFFADLVN SFGSNSNNVE KMMEEVLKYA LYFLVVGAAI WASSWAEISC WMWSGERQTT 120
  121 KMRIKYLEAA LNQDIQFFDT EVRTSDVVFA INTDAVMVQD AISEKLGNFI HYMATFVSGF 180
  181 IVGFTAVWQL ALVTLAVVPL IAVIGGIHTT TLSKLSNKSQ ESLSQAGNIV EQTVVQIRVV 240
  241 MAFVGESRAS QAYSSALKIA QKLGYKTGLA KGMGLGATYF VVFCCYALLL WYGGYLVRHH 300
  301 LTNGGLAIAT MFAVMIGGLA LGQSAPSMAA FAKAKVAAAK IFRIIDHKPT IERNSESGVE 360
  361 LDSVTGLVEL KNVDFSYPSR PDVKILNNFC LSVPAGKTIA LVGSSGSGKS TVVSLIERFY 420
  421 DPNSGQVLLD GQDLKTLKLR WLRQQIGLVS QEPALFATSI KENILLGRPD ADQVEIEEAA 480
  481 RVANAHSFII KLPDGFDTQV GERGLQLSGG QKQRIAIARA MLKNPAILLL DEATSALDSE 540
  541 SEKLVQEALD RFMIGRTTLI IAHRLSTIRK ADLVAVLQQG SVSEIGTHDE LFSKGENGVY 600
  601 AKLIKMQEAA HETAMSNARK SSARPSSARN SVSSPIMTRN SSYGRSPYSR RLSDFSTSDF 660
  661 SLSIDASSYP NYRNEKLAFK DQANSFWRLA KMNSPEWKYA LLGSVGSVIC GSLSAFFAYV 720
  721 LSAVLSVYYN PDHEYMIKQI DKYCYLLIGL SSAALVFNTL QHSFWDIVGE NLTKRVREKM 780
  781 LSAVLKNEMA WFDQEENESA RIAARLALDA NNVRSAIGDR ISVIVQNTAL MLVACTAGFV 840
  841 LQWRLALVLV AVFPVVVAAT VLQKMFMTGF SGDLEAAHAK GTQLAGEAIA NVRTVAAFNS 900
  901 EAKIVRLYTA NLEPPLKRCF WKGQIAGSGY GVAQFCLYAS YALGLWYASW LVKHGISDFS 960
  961 KTIRVFMVLM VSANGAAETL TLAPDFIKGG QAMRSVFELL DRKTEIEPDD PDTTPVPDRL1020
 1021 RGEVELKHID FSYPSRPDIQ IFRDLSLRAR AGKTLALVGP SGCGKSSVIS LIQRFYEPSS1080
 1081 GRVMIDGKDI RKYNLKAIRK HIAIVPQEPC LFGTTIYENI AYGHECATEA EIIQAATLAS1140
 1141 AHKFISALPE GYKTYVGERG VQLSGGQKQR IAIARALVRK AEIMLLDEAT SALDAESERS1200
 1201 VQEALDQACS GRTSIVVAHR LSTIRNAHVI AVIDDGKVAE QGSHSHLLKN HPDGIYARMI1260
 1261 QLQRFTHTQV IGMTSGSSSR VKEDDA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..667] PSI-BLAST 152.0 No description for 2hydA was found.
    2 View Details [668..1286] PSI-BLAST 150.0 No description for 3b5xA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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